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pro vyhledávání: '"JohnMark Derryberry"'
Publikováno v:
Biochemistry. 49:7108-7118
Expanded polyglutamine (polyQ) tracts are responsible for at least nine neurodegenerative diseases, including Huntington’s Disease (HD). HD occurs when the polyQ domain of exon 1 of huntingtin protein expands beyond a threshold of approximately 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f826679622a3a4ee6bdabeec0a51b0ac
https://doi.org/10.1021/bi1006095
https://doi.org/10.1021/bi1006095
Publikováno v:
Biophysical Journal. 97(8):2295-2305
PolyQ peptides teeter between polyproline II (PPII) and beta-sheet conformations. In tandem polyQ-polyP peptides, the polyP segment tips the balance toward PPII, increasing the threshold number of Gln residues needed for fibrillation. To investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0879e6e8f2d23b25c164c90b5e20032
Autor:
David Y. Gin, Yong-Jae Kim, JohnMark Derryberry, Bridget D Rohde, Pengfei Wang, Mauricio Navarro-Villalobos
Publikováno v:
Journal of the American Chemical Society. 128(36)
QS-21 is one of the most promising new adjuvants for immune response potentiation and dose-sparing in vaccine therapy given its exceedingly high level of potency and its favorable toxicity profile. Melanoma, breast cancer, small cell lung cancer, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515dd45792d58c13faa138479d114145
https://pubmed.ncbi.nlm.nih.gov/16953631
https://pubmed.ncbi.nlm.nih.gov/16953631