Zobrazeno 1 - 4
of 4
pro vyhledávání: '"John Zongrone"'
Autor:
Sally A. McCreedy, Kris E. Kucera, David J. Triggle, Matthew Marler, Roberta Mihut, E. S. C. Wu, Jack Gordon, Mary L. Stagnitto, Dan Widzowski, Andrew Howell, Anthony C. Machulskis, John Zongrone, Paul Bialobok, George B. Mullen, Marilyn K. Knowles, Shawn Sitar, James C. Blosser
Publikováno v:
Drug Development Research. 40:117-132
The purpose of these studies was to determine the levels of intrinsic activity in vitro at muscarinic receptor pharmacological subtypes (M1, M2, and M3) that would optimize cognitive activity while minimizing acute adverse cholinergic effects in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e8998ab434e05f533027b5fd6d29250
https://doi.org/10.1002/(sici)1098-2299(199702)40:2<117::aid-ddr3>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199702)40:2<117::aid-ddr3>3.0.co
Autor:
Alexander Rochester New York Us Kover, James T. Loch, L.Paul Rosenberg, Simon F. Semus, John Zongrone, Anthony C. Machulskis, James C. Blosser, John C. Gordon, Patrick R. Verhoest, Sally A. McCreedy, Edwin S. C. Wu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2525-2530
To improve receptor binding affinity and to investigate functional selectivity of 2,8-dimethyl-1-oxa-8-azaspiro[4.5]decan-3-one acetylhydrazone 2 at muscarinic receptor subtypes, a series of acylhydrazones A was synthesized. The SAR indicates that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb889704e941189ecb0b2cf85e52420e
https://doi.org/10.1016/0960-894x(96)00471-4
https://doi.org/10.1016/0960-894x(96)00471-4
Autor:
James J. Napier, Jack Gordon, Eifion Phillips, John Zongrone, David Gurley, Yanyi Zhu, Thomas DeCory, James T. Loch, Ronald Griffith, Alexander Kover, Michael Balestra, Anthony Sampognaro, George B. Mullen, and Alan Rosen, Patrick Verhoest, James Blosser, Robert J. Murray, Anthony Machulskis, Gregory Hale, Robert A. Mack, John Macor, Ed Wu
Publikováno v:
Journal of medicinal chemistry. 43(22)
Neuronal nicotinic acetylcholine receptors are members of the ligand-gated ion channel receptor superfamily and may play important roles in modulating neurotransmission, cognition, sensory gating, and anxiety. Because of its distribution and abundanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7659d6277e7dfd2b348e93e3d324db76
https://pubmed.ncbi.nlm.nih.gov/11063601
https://pubmed.ncbi.nlm.nih.gov/11063601
Publikováno v:
American Journal of Obstetrics and Gynecology. 157:1126-1128
A case of hyperreactio luteinalis is presented with measurements of human chorionic gonadotropin, total and free testosterone, and estriol throughout two term pregnancies. Ovulation induction with menotropins resulted in one spontaneous first-trimest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571477f149295a2317180a67d72f0cd0
https://doi.org/10.1016/s0002-9378(87)80275-2
https://doi.org/10.1016/s0002-9378(87)80275-2