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Autor:
Henry Simpkins, John Zihou Chen, Monika Wrzolek, Jianli Chen, Fiona Simpkins, Visitacion Pabicon, Rong Wu
Publikováno v:
American Journal of Biomedical and Life Sciences. 7:110
Dihydrodiol dehydrogenases (DDHs) belong to a superfamily of cytosolic NADP (H)-dependent oxidoreductases. The over-expression of DDHs induces cisplatin resistance. 2-Deoxy-D-glucose (2-DG), a glucose analogue, is currently being used as an anticance