Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John Z, Chen"'
Publikováno v:
eLife, Vol 9 (2020)
Metallo-β-lactamases (MBLs) degrade a broad spectrum of β-lactam antibiotics, and are a major disseminating source for multidrug resistant bacteria. Despite many biochemical studies in diverse MBLs, molecular understanding of the roles of residues
Externí odkaz:
https://doaj.org/article/58edc4ce86414b42971f26f76c1fbad1
Publikováno v:
Pharmaceutical Research. 39:3021-3028
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58d54fb037a328cd846079ce3a18af84
https://doi.org/10.1007/s11095-022-03388-7
https://doi.org/10.1007/s11095-022-03388-7
Autor:
Ayşe N. Erdoğan, Pouria Dasmeh, Raymond D. Socha, John Z. Chen, Ben Life, Rachel Jun, Linda Kiritchkov, Dan Kehila, Adrian W.R. Serohijos, Nobuhiko Tokuriki
Phenotypic variations within a population exist on different scales of biological organization and play a central role in evolution by providing adaptive capacity at the population-level. Thus, the question of how evolution generates phenotypic varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0e4da144f20356694589af31535b85
https://doi.org/10.1101/2023.04.05.535609
https://doi.org/10.1101/2023.04.05.535609
Publikováno v:
KONA Powder and Particle Journal, Vol 15, Iss 0, Pp 113-120 (2014)
Mechanofusion (MF) is a unique high energy powder processing technique, in which powder characteristics can be significantly modified. The effects of MF on powdered materials depend on MF operating conditions and the starting powders. This paper prop
Externí odkaz:
https://doaj.org/article/4e464b9815c844f596528cc57f04573f
Autor:
Brynn M. Murphy, John Z. Chen, Michael Rolo, Mohamed Eldam, Lynn Jordan, Sandra J. Sivananthan, Robert Kinsey, Jeffrey A. Guderian, Karl Pedersen, Mayuresh Abhyankar, William A. Petri, Christopher B. Fox, Warren H. Finlay, Reinhard Vehring, Andrew R. Martin
Publikováno v:
International journal of pharmaceutics. 626
Amebiasis, a disease caused by the parasite Entamoeba histolytica, is estimated to cause millions of infections and at least 55,000 deaths globally each year. With no vaccine currently available, there is an urgent need for an accessible means of sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38688bd39f47e6cb26c6649d26d5c546
https://pubmed.ncbi.nlm.nih.gov/36058408
https://pubmed.ncbi.nlm.nih.gov/36058408
Publikováno v:
Journal of Molecular Biology. 431:1172-1185
Genetic variation among orthologous genes has been largely formed through neutral genetic drift while maintaining the functional role of these genes. However, because the evolution of gene occurs in the context of each host organism, their sequence c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23383b0d4312e431c7e027d9418a38b
https://doi.org/10.1016/j.jmb.2019.01.041
https://doi.org/10.1016/j.jmb.2019.01.041
Publikováno v:
Protein engineering, designselection : PEDS. 34
This is a pre-copyedited, author-produced version of an article accepted for publication in Protein Engineering Design & Selection following peer review. The version of record Fröhlich, C.F., Chen, J.Z., Gholipour, S., Erdogan, A.N. & Tokuriki, N. (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1055f4d6cf24947dd3d790885821eb
https://pubmed.ncbi.nlm.nih.gov/34100551
https://pubmed.ncbi.nlm.nih.gov/34100551
Publikováno v:
Methods in enzymology. 643
Epistasis occurs when the combined effect of two or more mutations differs from the sum of their individual effects, and reflects molecular interactions that affect the function and fitness of a protein. Epistasis is widely recognized as a key phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97d11d5c85513dfa1f3ba809d48b5596
https://pubmed.ncbi.nlm.nih.gov/32896284
https://pubmed.ncbi.nlm.nih.gov/32896284
Epistasis occurs when the combined effect of two or more mutations differs from the sum of their individual effects, and reflects molecular interactions that affect the function and fitness of a protein. Epistasis is widely recognized as a key phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce2dfe873b6496eecb58ac0fbdb6cece
https://doi.org/10.1016/bs.mie.2020.07.012
https://doi.org/10.1016/bs.mie.2020.07.012