Zobrazeno 1 - 10
of 90
pro vyhledávání: '"John Y. Kuwada"'
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Stac3 regulates excitation-contraction coupling (EC coupling) in vertebrate skeletal muscles by regulating the L-type voltage-gated calcium channel (Cav channel). Recently a stac-like gene, Dstac, was identified in Drosophila and found to be expresse
Externí odkaz:
https://doaj.org/article/4d5487f3d3204588bf7575bb932ab900
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Axons of the peripheral nervous system regenerate along Schwann cells following injury. Here, the authors show that regenerating axons follow pioneer axons and this process is mediated by lipoprotein receptor-related protein 4 (Lrp4), a protein other
Externí odkaz:
https://doaj.org/article/64b3962177964d1280be358fae515cc7
Autor:
Jeremy W. Linsley, Nadia Perez, I-Uen Hsu, Yuyang Yang, Naveen Jasti, Matthew Waalkes, Eric J. Horstick, John Y. Kuwada
The stac family of genes are expressed by several cell types including neurons and muscles in a wide variety of animals. In vertebrates, stac3 encodes an adaptor protein specifically expressed by skeletal muscle that regulates L-type calcium channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c8abe0dbe4f9a70f8841d2f814173d
https://doi.org/10.1101/2022.08.24.505176
https://doi.org/10.1101/2022.08.24.505176
Autor:
Allison M Orzel, Richard I. Hume, Miranda C Lum, Lilly E. Reid, Catherine A. Collins, Jade E Varineau, Edwin S. Levitan, John Y. Kuwada, Haoxing Xu, Ari Leflein, Xiaoli Zhang, Jeremy W. Linsley, Drew A Berkhoudt, I-Uen Hsu
Publikováno v:
Proc Natl Acad Sci U S A
Significance Many neurons release neuropeptides as well as classical neurotransmitters. Neuropeptides often regulate neural circuits controlling behaviors such as emotional behaviors. However, how neuropeptide release is regulated is not well-underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144c861eee26045445989fff66ac1a7a
https://doi.org/10.1073/pnas.2009224117
https://doi.org/10.1073/pnas.2009224117
Publikováno v:
Chronobiology international. 35(7)
The genetic, molecular and neuronal mechanism underlying circadian activity rhythms is well characterized in the brain of Drosophila. The small ventrolateral neurons (s-LN(V)s) and pigment dispersing factor (PDF) expressed by them are especially impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1b8903f81adaa8cd6bce416afa297c
https://pubmed.ncbi.nlm.nih.gov/29621409
https://pubmed.ncbi.nlm.nih.gov/29621409
Contraction of skeletal muscle is initiated by excitation-contraction (EC) coupling during which membrane voltage is transduced to intracellular Ca2+ release. EC coupling requires L-type voltage gated Ca2+ channels (the dihydropyridine receptor or DH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b1c44a79c6d9fa4bb833c8c4ffd03c
https://europepmc.org/articles/PMC5569907/
https://europepmc.org/articles/PMC5569907/
The zebrafish curly fry (cfy) mutation leads to a dramatic increase in mitotic index and cell death starting during neural tube formation. The mutant phenotype is cell autonomous and does not result from defects in apical/basal polarity within the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0970a8bb68e07bb5f0de294c30300924
https://europepmc.org/articles/PMC5549795/
https://europepmc.org/articles/PMC5549795/
Autor:
Drew Linsley, Jeremy W. Linsley, Robert T. Dirksen, Eric J. Horstick, Wenjia Wang, Clara Franzini-Armstrong, John Y. Kuwada, Manuela Lavorato, Viktor Yarotskyy, I-Uen Hsu, Linda Groom
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(2)
Skeletal muscle contractions are initiated by an increase in Ca2+ released during excitation–contraction (EC) coupling, and defects in EC coupling are associated with human myopathies. EC coupling requires communication between voltage-sensing dihy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd7788a68731fd757ffc6326700a1e3
https://pubmed.ncbi.nlm.nih.gov/28003463
https://pubmed.ncbi.nlm.nih.gov/28003463
Autor:
Koichi Kawakami, Louis Saint-Amant, Kazutoyo Ogino, John Y. Kuwada, Kazuhide Asakawa, Yuriko Naganawa, Yu Kawakami, Hiromi Hirata, Weibin Zhou, Kenta Yamada, Sean E. Low, Hua Wen, Akira Muto, Shawn M. Sprague, Wilson W. Cui
Publikováno v:
Journal of Biological Chemistry. 287:1080-1089
In many tissues and organs, connexin proteins assemble between neighboring cells to form gap junctions. These gap junctions facilitate direct intercellular communication between adjoining cells, allowing for the transmission of both chemical and elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea5199e1ab37b07babe990ced95ce13
https://doi.org/10.1074/jbc.m111.308205
https://doi.org/10.1074/jbc.m111.308205
Autor:
Jeremy W. Linsley, Louis Saint-Amant, Wilson W. Cui, Richard I. Hume, Eric J. Horstick, Kimberly Amburgey, Weibin Zhou, John Y. Kuwada, Hiromi Hirata, Sean E. Low, Shawn M. Sprague
Publikováno v:
The Journal of Neuroscience. 31:11633-11644
Mutations in the gene encoding TRPM7 (trpm7), a member of the Transient Receptor Potential (TRP) superfamily of cation channels that possesses an enzymatically active kinase at its C terminus, cause the touch-unresponsive zebrafish mutanttouchdown. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed49ed74441f4148e6aceb6cabe5245
https://doi.org/10.1523/jneurosci.4950-10.2011
https://doi.org/10.1523/jneurosci.4950-10.2011