Zobrazeno 1 - 10
of 21
pro vyhledávání: '"John Y, Dong"'
Autor:
Danher Wang, Joy Gardner, Thuy T. Le, Adam Penn-Nicholson, Itaru Anraku, David Einfeld, John Y. Dong, Jan Woraratanadharm, Min Luo, Andreas Suhrbier, Michael Sakalian
Publikováno v:
Vaccine. 29:2803-2809
Chikungunya virus, a mosquito-borne alphavirus, recently caused the largest epidemic ever seen for this virus. Chikungunya disease primarily manifests as a painful and debilitating arthralgia/arthritis, and no effective drug or vaccine is currently a
Autor:
William D. Pratt, Danher Wang, John M. Dye, Donald K. Nichols, Min Luo, Jan Woraratanadharm, David H. Holman, John Y. Dong
Publikováno v:
Clinical and Vaccine Immunology. 17:572-581
Ebola viruses are highly pathogenic viruses that cause outbreaks of hemorrhagic fever in humans and other primates. To meet the need for a vaccine against the several types of Ebola viruses that cause human diseases, we developed a multivalent vaccin
Autor:
Jan Woraratanadharm, Adam Penn-Nicholson, Danher Wang, David H. Holman, John Y. Dong, Ellen M. Maher, Min Luo, Michael R. Holbrook, Mary-Katherine Harr
Publikováno v:
Clinical and Vaccine Immunology. 16:1624-1632
Rift Valley fever virus (RVFV) has been cited as a potential biological-weapon threat due to the serious and fatal disease it causes in humans and animals and the fact that this mosquito-borne virus can be lethal in an aerosolized form. Current human
Autor:
Kevin R. Porter, John Y. Dong, Jan Woraratanadharm, Danher Wang, Karla Block, David H. Holman, Daniel Ewing, Curtis G. Hayes, Kanakatte Raviprakash, Lan Chen
Publikováno v:
Journal of Virology
Nearly a third of the human population is at risk of infection with the four serotypes of dengue viruses, and it is estimated that more than 100 million infections occur each year. A licensed vaccine for dengue viruses has become a global health prio
Autor:
John Y. Dong, David H. Holman, Danher Wang, Nicholas U. Raja, Nutan Mytle, Min Luo, Kevin M. Moore, Jan Woraratanadharm
Publikováno v:
Vaccine. 26:2627-2639
There are legitimate concerns that the highly pathogenic H5N1 avian influenza virus could adapt for human-to-human transmission and cause a pandemic similar to the 1918 "Spanish flu" that killed 50 million people worldwide. We have developed pandemic
Autor:
John Y. Dong, William D. Pratt, Danher Wang, Kelly L. Warfield, Dana L. Swenson, Jan Woraratanadharm, Min Luo, David H. Holman
Publikováno v:
Clinical and Vaccine Immunology. 15:460-467
Filoviruses (Ebola and Marburg viruses) are among the deadliest viruses known to mankind, with mortality rates nearing 90%. These pathogens are highly infectious through contact with infected body fluids and can be easily aerosolized. Additionally, t
Autor:
Laure Y. Juompan, Jianghui Zhang, Nicholas U. Raja, David H. Holman, Stephen B. Deitz, Danher Wang, Min Luo, Kevin R. Porter, John Y. Dong, Kanakatte Raviprakash
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 76:743-751
There are approximately 100 million new cases of dengue (DEN) virus infection each year. Infection can result in illness ranging from a mild fever to hemorrhaging, shock, or even death. There are four serotypes of dengue virus (DEN1-4), and immunity
Autor:
Danher Wang, Kanakatte Raviprakash, Nicholas U. Raja, Kevin R. Porter, Jianghui Zhang, John Y. Dong, Min Luo, David H. Holman
Publikováno v:
Clinical and Vaccine Immunology
Dengue virus infections can cause hemorrhagic fever, shock, encephalitis, and even death. Worldwide, approximately 2.5 billion people live in dengue-infested regions with about 100 million new cases each year, although many of these infections are be
Autor:
Min Luo, Stephen B. Deitz, Michael Hevey, Laure Y. Juompan, Charles M. Trubey, Kevin M. Moore, Jan Woraratanadharm, Nicholas U. Raja, Hong Yu, Danher Wang, John Y. Dong, Benjamin M. Swain
Publikováno v:
Virology. 353(2):324-332
The Marburg virus (MARV), an African filovirus closely related to the Ebola virus, causes a deadly hemorrhagic fever in humans, with up to 90% mortality. Currently, treatment of disease is only supportive, and no vaccines are available to prevent spr
Autor:
Charles M. Trubey, Nicholas U. Raja, Alan L. Schmaljohn, Benjamin M. Swain, William D. Pratt, Kevin M. Moore, Min Luo, Hong Yu, Danher Wang, David H. Holman, Jan Woraratanadharm, Laure Y. Juompan, John Y. Dong, Stephen B. Deitz
Publikováno v:
Vaccine. 24:2975-2986
Marburg virus (MARV) is an African filovirus that causes a deadly hemorrhagic fever in humans, with up to 90% mortality. Currently, there are no MARV vaccines or therapies approved for human use. We hypothesized that developing a vaccine that induces