Zobrazeno 1 - 10
of 18
pro vyhledávání: '"John Wojcieszyn"'
Publikováno v:
Journal of Avian Medicine and Surgery. 28:50-56
An unknown-age, adult female ring-necked dove (Streptopelia risoria) was presented with an ulcerated mass on the medial side of the right tibiotarsus. Radiographs revealed severe boney lysis with proliferative periosteal reaction. Surgical amputation
Autor:
Jerold Bell, B. E. Greenfield, Victor E. Valli, Rachael Thomas, Jaime F. Modiano, Susan Fosmire, T. L. Smith, Cristan M. Jubala, Lori A. Gardner, William C. Kisseberth, Susan E. Lana, K. P. Freeman, David M. Getzy, Matthew Breen, John Wojcieszyn, Stuart C. Helfand, Gary Cutter, Michelle G. Ritt
Publikováno v:
Veterinary Pathology. 44:467-478
The significance of p16/Rb tumor suppressor pathway inactivation in T-cell non-Hodgkin's lymphoma (NHL) remains incompletely understood. We used naturally occurring canine NHL to test the hypothesis that p16 inactivation has specific pathologic corre
Autor:
John Wojcieszyn, Donald Bellgrau, Jaime F. Modiano, Cristan M. Jubala, David M. Getzy, Victor E. Valli, Susan Fosmire, D. Coffey
Publikováno v:
Veterinary Pathology. 42:468-476
We examined the expression of CD20 in normal canine peripheral blood mononuclear cells, normal canine spleen, and canine non-Hodgkin lymphoma (NHL) to determine the feasibility of using this antigen as a diagnostic aid and as a possible target for th
Autor:
Michelle G. Ritt, Claudia L Barton, Roger Smith, Jaime F. Modiano, Jocelyne Mayor, John Wojcieszyn
Publikováno v:
Cancer Letters. 158:73-84
We assessed the expression and distribution of p21/Waf-1 in TLM1 melanoma cells that exhibit contact inhibition and require serum for growth. The growth stage of cells stimulated to enter the mitotic cell cycle synchronously and grow to confluence wa
Publikováno v:
Journal of Veterinary Internal Medicine. 13:163-174
Publikováno v:
DNA and Cell Biology. 18:357-367
Both growth-factor deprivation and contact inhibition suppress cell growth; however, the mechanisms by which they inhibit cell proliferation may not be identical. The function of antiproliferative genes and the induction of programmed cell death are
Publikováno v:
Veterinary Pathology. 35:94-101
Mutations of tumor suppressor genes remove mechanisms that normally arrest proliferation of transformed cells, resulting in tumor formation. The p53 gene product functions as a tumor suppressor that induces p21/Waf-1, the 21-kDa product of the waf-1/
Publikováno v:
Leukemia. 21(1)
Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma
Autor:
Erin B. Dickerson, A. R. Lamerato-Kozicki, Jaime F. Modiano, Matthew Breen, John Wojcieszyn, Susan Fosmire, Stuart C. Helfand, Rachael Thomas, Stacie R Bianco
Publikováno v:
Veterinary pathology. 42(5)
We examined the presence of phosphatase and tensin homolog deleted from chromosome 10 (PTEN) abnormalities that could contribute to the origin or progression of naturally occurring canine endothelial tumors (hemangiosarcoma). Our results document som
Autor:
Nasim Akhtar, Heather Meylemans, Stacie R Bianco, Marilyn J Pettengill, Jaime F. Modiano, Erin B. Dickerson, Susan Fosmire, Marcia L. Padilla, John Wojcieszyn, David M. Getzy, Matthew Breen, Ashley Frazer-Abel, Stuart C. Helfand, A. Scott
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 84(5)
Hemangiosarcoma (HSA) is a common untreatable cancer of dogs that resembles human angiosarcoma. Detailed studies of these diseases have been historically hindered by the paucity of suitable reagents. Here, we show that expression of CD117 (c-Kit) can