Zobrazeno 1 - 4
of 4
pro vyhledávání: '"John William Warmenhoven"'
Autor:
Samuel P. Ingram, John-William Warmenhoven, Nicholas T. Henthorn, Amy L. Chadiwck, Elham E. Santina, Stephen J. McMahon, Jan Schuemann, Norman F. Kirkby, Ranald I. Mackay, Karen J. Kirkby, Michael J. Merchant
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
PyFoci is a tool that simulates distributions of fluorescently labeled DNA double-strand break marker protein foci and allows the estimation of miscounting under different radiation types, doses and microscopy settings.
Externí odkaz:
https://doaj.org/article/12f2d24396fc42b6b08bfd133060527c
Autor:
Hannah C Wanstall, Nicholas T Henthorn, James Jones, Elham Santina, Amy L Chadwick, Deepa Angal-Kalinin, Geoffrey Morris, John-William Warmenhoven, Rob Smith, Storm Mathisen, Michael J Merchant, Roger M Jones
Publikováno v:
Journal of Radiation Research. 64:547-557
The pBR322 plasmid DNA was irradiated with 35 MeV electrons, 228 MeV protons and 300 kVp X-rays to quantify DNA damage and make comparisons of DNA damage between radiation modalities. Plasmid was irradiated in a medium containing hydroxyl radical sca
Autor:
Charlotte J Heaven, Hannah C Wanstall, Nicholas T Henthorn, John-William Warmenhoven, Samuel P Ingram, Amy L Chadwick, Elham Santina, Jamie Honeychurch, Christine K Schmidt, Karen J Kirkby, Norman F Kirkby, Neil G Burnet, Michael J Merchant
Publikováno v:
Heaven, C J, Wanstall, H C, Henthorn, N T, Warmenhoven, J-W, Ingram, S P, Chadwick, A L, Santina, E, Honeychurch, J, Schmidt, C K, Kirkby, K J, Kirkby, N F, Burnet, N G & Merchant, M J 2022, ' The suitability of micronuclei as markers of relative biological effect ', Mutagenesis, vol. 37, no. 1, pp. 3-12 . https://doi.org/10.1093/mutage/geac001
Mutagenesis
Mutagenesis
Micronucleus (MN) formation is routinely used as a biodosimeter for radiation exposures and has historically been used as a measure of DNA damage in cells. Strongly correlating with dose, MN are also suggested to indicate radiation quality, different
Autor:
Alejandro, Bertolet, José, Ramos-Méndez, Aimee, McNamara, Dohyeon, Yoo, Samuel, Ingram, Nicholas, Henthorn, John-William, Warmenhoven, Bruce, Faddegon, Michael, Merchant, Stephen J, McMahon, Harald, Paganetti, Jan, Schuemann
Publikováno v:
Radiation Research. 198
Track structure Monte Carlo simulations are a useful tool to investigate the damage induced to DNA by ionizing radiation. These simulations usually rely on simplified geometrical representations of the DNA subcomponents. DNA damage is determined by t