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pro vyhledávání: '"John Wang-Hu"'
Autor:
Jourdon Robinson, Xiefan Fang, Daniel Freeman, John Wang-Hu, Christopher C. Wendler, Lingli Jiang, Scott A. Rivkees
Publikováno v:
American Journal of Physiology-Cell Physiology. 309:C425-C436
cAMP is a highly regulated secondary messenger involved in many biological processes. Chronic activation of the cAMP pathway by catecholamines results in cardiac hypertrophy and fibrosis; however, the mechanism by which elevated cAMP leads to cardiom
Autor:
Ryan R. Poulsen, Olivia Shi, Nicholas S. Calvo, Chelsey S. Simmons, Christopher C. Wendler, John Wang-Hu, Scott A. Rivkees, Xiefan Fang
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(9)
We previously found that in utero caffeine exposure causes down-regulation of DNA methyltransferases (DNMTs) in embryonic heart and results in impaired cardiac function in adulthood. To assess the role of DNMTs in these events, we investigated the ef