Zobrazeno 1 - 10 of 38 pro vyhledávání: '"John W. Wilks"'
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Synthesis of [1, 6-cyclo(Acetyl-1-L-glutamic acid, 2-D-phenylalanine, 3-D-tryptophan, 6-D-lysine)] luteinizing hormone-releasing hormone on poly-N-acrylylpyrrolidine resin
Autor: Gerald Skala, John W. Wilks, Clark W. Smith
Publikováno v: International Journal of Peptide and Protein Research. 21:127-134
The protected peptide, Ac-Glu(OBut)-D-Phe-D-Trp-Ser(But)-Tyr(But)-D-Lys (Z)-Leu-Arg(Tos)-Pro-Gly-NH2 was synthesized in a stepwise manner on a resin of poly-N-acrylylpyrrolidine using both acid cleavable N alpha-tert.-butyloxycarbonyl and base cleava
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc51410c96951f6e744e1a1b881a072
https://doi.org/10.1111/j.1399-3011.1983.tb03086.x
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2
Sensitive Assay for Antifungal Activity of Glucan Synthase Inhibitors That Uses Germ Tube Formation in Candida albicans as an End Point
Autor: Timothy G. Brayman, John W. Wilks
Publikováno v: Antimicrobial Agents and Chemotherapy. 47:3305-3310
We implemented a simple, sensitive, objective, and rapid cellular assay to reveal the antifungal activity of a novel class of glucan synthase inhibitors. The assay, especially useful for early drug discovery, measures the transformation of Candida al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb179a8f8ff515331aedb8460f95f5c6
https://doi.org/10.1128/aac.47.10.3305-3310.2003
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4
Chapter 15. Inhibitors of Angiogenesis
Autor: John W. Wilks, Mark A. Mitchell
Publisher Summary This chapter discusses the recent progress in identifying the key cellular and molecular features of angiogenesis and illustrates the recent novel compounds that have potential clinical utility. Among the in vivo assays, the chicken
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cadd5fda3b7d7ec687a4266e051a982e
https://doi.org/10.1016/s0065-7743(08)60413-3
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5
Luteolytic action of 15-keto prostaglandin F2α in the rhesus monkey
Autor: John W. Wilks
Publikováno v: Prostaglandins. 13:161-170
The naturally-occurring metabolite of prostaglandin F2alpha, 15-keto prostaglandin F2alpha (15-keto PGF2alpha), elicited rapid and sustained declines in serum progesterone concentrations when administered to rhesus monkeys beginning on day 22 of norm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c483b67633204ae115ce793e8639abce
https://doi.org/10.1016/0090-6980(77)90053-3
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6
Inhibition of the primate ovarian cycle by a porcine follicular fluid protein(s)
Autor: Gere S. diZerega, John W. Wilks
Publikováno v: Fertility and Sterility. 41:635-638
Monkeys received twice daily intramuscular injections of 3mg of purified porcine follicular fluid protein(s) for the first 14.5days of the menstrual cycle. Two of five treated monkeys had anovulatory menstrual cycles. Three monkeys had cycles charact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::396c0e729bda9ac6409d80e8ffb45b29
https://doi.org/10.1016/s0015-0282(16)47791-5
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7
Persistence of progesterone secretion after foetal death induced by vasopressin in rabbits
Autor: John W. Wilks
Publikováno v: Acta Endocrinologica. 97:569-572
Synthetic lysine-vasopressin (2 IU/kg body weight) terminated pregnancy in the rabbit when administered im on day 20, but not when administered on days 8 through 11 of gestation. Rabbits treated with vasopressin on day 20 delivered necrotic foetuses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02329551b60e34b05912d57ec11e274
https://doi.org/10.1530/acta.0.0970569
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8
Additional studies on pregnancy termination and inhibition of the monkey corpus luteum with 5-oxa-17-phenyl-18,19,20-trinor-PGF1α methyl ester and structurally related prostaglandins
Autor: John W. Wilks, Norman A. Nelson
Publikováno v: Prostaglandins. 28:323-332
Oral administration of 5-oxa-17-phenyl-18,19,20-trinor-PGF 1α methyl ester (PGF-analog) resulted in a consistent and dose-dependent inhibition of corpus luteum progesterone production in nonpregnant rhesus monkeys concomitantly treated with human ch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce19aa73976f28f559269406e686660
https://doi.org/10.1016/0090-6980(84)90020-0
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9
Inhibition of folliculogenesis in the monkey following early follicular phase administration of an LRH agonist
Autor: John W. Wilks
Publikováno v: Acta Endocrinologica. 106:538-543
This study was undertaken to determine if early follicular phase administration of a synthetic luteinizing hormone releasing hormone (LRH) agonist would produce luteal phase defects in the monkey. (D-His-(im-Bzl)6,Pro9]LRH n-ethylamide was administer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b863aef3016df371998118e41f1421f
https://doi.org/10.1530/acta.0.1060538
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10
Periovulatory Endocrine Events in the Stumptailed Monkey (Macaca arctoides)*
Autor: Gary D. Hodgen, John W. Wilks, David L. Hildebrand, Richard D. Marciniak
Publikováno v: Endocrinology. 107:237-244
Blood samples were obtained frequently from stumptailed monkeys (Macaca arctoides) at midcycle and assayed for FSH, LH, 17 beta-estradiol, and progesterone. Periovulatory endocrine events were generally similar to those which have been described in r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fb181a88c3ee85c04fa98782964b42
https://doi.org/10.1210/endo-107-1-237
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