Zobrazeno 1 - 10
of 224
pro vyhledávání: '"John W. Smith"'
Autor:
Falon C. Kalutantirige, Jinlong He, Lehan Yao, Stephen Cotty, Shan Zhou, John W. Smith, Emad Tajkhorshid, Charles M. Schroeder, Jeffrey S. Moore, Hyosung An, Xiao Su, Ying Li, Qian Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Voids—the nothingness—broadly exist within nanomaterials and impact properties ranging from catalysis to mechanical response. However, understanding nanovoids is challenging due to lack of imaging methods with the needed penetration dept
Externí odkaz:
https://doaj.org/article/cb886f4478ca46fe934ad2200a4f1bc2
Autor:
Costanza Paoletti, Meredith M. Regan, Samuel M. Niman, Emily M. Dolce, Elizabeth P. Darga, Minetta C. Liu, P. Kelly Marcom, Lowell L. Hart, John W. Smith, Karen L. Tedesco, Eitan Amir, Ian E. Krop, Angela M. DeMichele, Pamela J. Goodwin, Margaret Block, Kimberly Aung, Martha E. Brown, Robert T. McCormack, Daniel F. Hayes
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Circulating tumor cells (CTC) are prognostic in metastatic breast cancer (MBC). The CTC-endocrine therapy index (CTC-ETI), consisting of CTC-ER (estrogen receptor), BCL2, human epidermal growth factor receptor (HER2), and Ki67 expression, mi
Externí odkaz:
https://doaj.org/article/a4591a6d3a9d4069a97a9133183bb04c
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Anisometric colloids—which have both nanometer and micrometer dimensions—combine features of their two constituent length scales. Here, using optical microscopy and modeling, the authors find that highly polydisperse anisometric colloids self-ass
Externí odkaz:
https://doaj.org/article/04b00e863a2f4a6dab7e6b96c20c4b71
Autor:
Lauren M. Childs, Fadoua El Moustaid, Zachary Gajewski, Sarah Kadelka, Ryan Nikin-Beers, John W. Smith, Jr, Melody Walker, Leah R. Johnson
Publikováno v:
PeerJ, Vol 7, p e7057 (2019)
The observed dynamics of infectious diseases are driven by processes across multiple scales. Here we focus on two: within-host, that is, how an infection progresses inside a single individual (for instance viral and immune dynamics), and between-host
Externí odkaz:
https://doaj.org/article/69d03e559eb046509e5fb42ce85e52af
Autor:
Frankie A. Holmes, Beverly Moy, Suzette Delaloge, Stephen K.L. Chia, Bent Ejlertsen, Janine Mansi, Hiroji Iwata, Michael Gnant, Marc Buyse, Carlos H. Barrios, Tajana Silovski, Robert Šeparović, Anna Bashford, Angel Guerrero Zotano, Neelima Denduluri, Debra Patt, Erhan Gokmen, Ira Gore, John W. Smith, Sibylle Loibl, Norikazu Masuda, Zorica Tomašević, Katarina Petráková, Daniel DiPrimeo, Alvin Wong, Miguel Martin, Arlene Chan
Publikováno v:
European Journal of Cancer. 184:48-59
ExteNET showed that neratinib, an irreversible pan-HER tyrosine ki- nase inhibitor, given for 1 year after trastuzumab-based therapy significantly improved inva- sive disease-free survival in women with early-stage HER2-positive breast cancer. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f52b3f56c3541c7f92ad50e9e346cad
https://doi.org/10.1016/j.ejca.2023.02.002
https://doi.org/10.1016/j.ejca.2023.02.002
Akademický článek
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Autor:
José Baselga, Alejandro Yovine, Diana Graus Porta, Andrea Kay, Yong Zhang, Michael Shi, Stephanie Deudon, John W. Smith, Hope Rugo, Nicholas Turner, Sara A. Hurvitz, Jose M. Perez-Garcia, Florence Dalenc, Mario Campone, Thomas Bachelot, Fabrice André
Purpose: Fibroblast growth factor receptor 1 (FGFR1) and FGFR2 amplifications are observed in approximately 10% of breast cancers and are related to poor outcomes. We evaluated whether dovitinib (TKI258), an inhibitor of FGFR1, FGFR2, and FGFR3, pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a5f9080cb69d3be9bef60e929cdae9
https://doi.org/10.1158/1078-0432.c.6522158.v1
https://doi.org/10.1158/1078-0432.c.6522158.v1
Autor:
José Baselga, Alejandro Yovine, Diana Graus Porta, Andrea Kay, Yong Zhang, Michael Shi, Stephanie Deudon, John W. Smith, Hope Rugo, Nicholas Turner, Sara A. Hurvitz, Jose M. Perez-Garcia, Florence Dalenc, Mario Campone, Thomas Bachelot, Fabrice André
PDF file - 20K, Dovitinib effectively targets FGFR1 in vivo. FGF23 levels were measured from plasma taken at baseline and during dovitinib treatment in 18, 33, and 20 patients from the FGFR1+/HR+, FGFR1-/HR+, and FGFR1-/HR- patient groups, respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfa9045e59c75ec46420f903696c98c
https://doi.org/10.1158/1078-0432.22451300
https://doi.org/10.1158/1078-0432.22451300
Autor:
José Baselga, Alejandro Yovine, Diana Graus Porta, Andrea Kay, Yong Zhang, Michael Shi, Stephanie Deudon, John W. Smith, Hope Rugo, Nicholas Turner, Sara A. Hurvitz, Jose M. Perez-Garcia, Florence Dalenc, Mario Campone, Thomas Bachelot, Fabrice André
PDF file - 61K, Growth Inhibition in FGFR1- and FGFR2-Amplified Cell Lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5be4b46df503ae901d9ead6b868c7c
https://doi.org/10.1158/1078-0432.22451297
https://doi.org/10.1158/1078-0432.22451297
Biological phenomena ranging from enzymatic catalysis to synaptic transmission find their origins in the morphological fluctuations of biomolecules and biomolecular assemblies in liquid water. However, directly imaging these nanoscopic dynamics witho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86fe15600c41b2f6a1755110f56e7a9
https://doi.org/10.1101/2022.11.13.516315
https://doi.org/10.1101/2022.11.13.516315