Zobrazeno 1 - 10
of 55
pro vyhledávání: '"John W. Shepherd"'
Autor:
Elizabeth V. Castro, John W. Shepherd, Ryan S. Guggenheim, Manimone Sengvoravong, Bailey C. Hall, McKenzie K. Chappell, Jessica A. Hearn, Olivia N. Caraccio, Cora Bissman, Sydney Lantow, Damian Buehner, Harry R. Costlow, David M. Prather, Abigail M. Zonza, Mallory Witt, Jeffrey A. Zahratka
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Ion channels are integral membrane protein complexes critical for regulation of membrane potential, cell volume, and other signaling events. As complex molecular assemblies with many interacting partners, ion channels have multiple structural and fun
Externí odkaz:
https://doaj.org/article/5bc9a44b001049f9b61703c75d62e4f4
Autor:
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1346 (2021)
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://doaj.org/article/d948abd924354895b2c5b1c46d082bd9
Autor:
Gregory P. Pogue, Steve Hume, Jennifer K. DeMarco, Josh Morton, John W. Shepherd, Jon D. Gabbard, Joshua M. Royal, Kelsi Swope, Barry Bratcher, Kenneth E. Palmer, William Severson, Carrie A. Simpson
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b329a7578b16d5aa6c0a5474182ec467
https://pubmed.ncbi.nlm.nih.gov/34835277
https://pubmed.ncbi.nlm.nih.gov/34835277
Autor:
Kevin J. Whaley, Barry Bratcher, Hugh Haydon, Carrie A. Simpson, Josh Morton, Keith R. Davis, Gregory P. Pogue, Michael H. Pauly, Steve Hume, Kelsi Swope, Larry Zeitlin, John W. Shepherd
Publikováno v:
Methods in Enzymology ISBN: 9780323907378
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aecff14492cc9515dbb7d65a83a54b4
https://doi.org/10.1016/bs.mie.2021.05.011
https://doi.org/10.1016/bs.mie.2021.05.011
Autor:
Joshua L Fuqua, John W. Shepherd, Krystal Teasley Hamorsky, Kenneth E. Palmer, Ernie Hiatt, Julia M. Corman
Publikováno v:
J Biotechnol
The “whole genome” TMV-based expression system, Geneware(®), was used in the cGMP production of the plant-made pharmaceutical Q-Griffithsin and demonstrates stable expression for up to a two-year period. Virion and plasmid banks which contained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4379dbda0143f7174f5956e6b249f87b
https://europepmc.org/articles/PMC7397727/
https://europepmc.org/articles/PMC7397727/
Autor:
Hugh Haydon, Amanda Phillips, Gregory P. Pogue, Robert W. Cross, Steve Hume, Joshua M. Royal, Jennifer DeBeauchamp, Thomas W. Geisbert, Josh Morton, Alison A. McCormick, John W. Shepherd, Carrie A. Simpson, Viktoriya Borisevich, Barry Bratcher, Jennifer K. DeMarco, Richard J. Webby, Kelsi Swope, Young Jun Oh
Publikováno v:
Vaccines, Vol 9, Iss 1347, p 1347 (2021)
Vaccines
Volume 9
Issue 11
Vaccines
Volume 9
Issue 11
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6906ad3b34797bf0600d09a380a93f8
https://doi.org/10.3390/vaccines9111347
https://doi.org/10.3390/vaccines9111347
The Effect of Maternal Depressed Mood on Infant Emotional Reaction in a Surprise-Eliciting Situation
Autor:
Nadja Reissland, John W. Shepherd
Publikováno v:
Infant mental health journal. 27(2)
The purpose of this study is to examine the claim that an infant's ability to respond appropriately to an emotional situation varies according to the emotional state of the mother. Surprise expressions in mother and child were examined both in terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68080b6fc9e8717a0819503e762069e6
https://pubmed.ncbi.nlm.nih.gov/28640411
https://pubmed.ncbi.nlm.nih.gov/28640411
Autor:
Adam Rutland, Daniel T. Smith, David P. Carey, Douglas Martin, Geoff Smith, John W. Shepherd, Jan Skriver
Publikováno v:
Cortex, 2009, Vol.45(5), pp.650-661
A strong preference for using the right foot for skilled activities parallels a similar side bias for hand use. However, many neuropsychologists, sports scientists and sports commentators argue that right-foot bias in soccer is reduced or even elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5d916d3e08d4594e2033d1963955c6
https://doi.org/10.1016/j.cortex.2008.05.011
https://doi.org/10.1016/j.cortex.2008.05.011
Publikováno v:
European Journal of Developmental Psychology. 2:271-283
Research suggests that some forms of maternal play can be interpreted positively leading to healthy development or have negative effects leading to emotional and cognitive vulnerability in children and adolescents. The purpose of this study is to rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d912ff6e5b65f51adcc51b8b045438e
https://doi.org/10.1080/17405620444000319
https://doi.org/10.1080/17405620444000319
Maternal touch and maternal child-directed speech: effects of depressed mood in the postnatal period
Publikováno v:
Journal of affective disorders, 2004, Vol.81(1), pp.29-39 [Peer Reviewed Journal]
Background: Postnatal depression affects the emotional state of mothers and the quality of mother–infant interaction. Method: Touch behaviour and content of child-directed speech were analysed for 72 mothers and their infants during pleasurable pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7aed2bd03026d9c3ee35b759052a48
https://doi.org/10.1016/j.jad.2003.07.001
https://doi.org/10.1016/j.jad.2003.07.001