Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John W. Sagartz"'
Publikováno v:
Inhalation Toxicology. 16:1-20
A subchronic, nose-only inhalation study compared the effects of mainstream smoke from a 1R4F research cigarette to that of a 2R4F research cigarette. Male and female rats were exposed for 1 h/day, 5 days/wk, for 13 wk to mainstream smoke at 0, 0.06,
Autor:
W. Keith Shreve, Arnold T. Mosberg, Steven Kinsler, Deborah H. Pence, John W. Sagartz, Paul H. Ayres
Publikováno v:
Inhalation Toxicology. 15:819-854
A subchronic, nose-only inhalation study compared the effects of mainstream smoke from a cigarette containing 100% flue-cured tobacco cured by a direct-fired process to that of a cigarette containing 100% flue-cured tobacco cured by a heat exchanger
Publikováno v:
Toxicologic Pathology. 21:542-546
Specific regions in the rodent larynx exhibit cellular changes in response to inhaled xenobiotics. These regions include the base of the epiglottis, ventral pouch, and medial surfaces of the vocal processes of the arytenoid cartilages. There are inte
Autor:
A. Wallace Hayes, Arnold T. Mosberg, Paul H. Ayres, John W. Sagartz, Christopher R. E. Coggins
Publikováno v:
Inhalation Toxicology. 5:97-115
This study was performed to evaluate the use of an alternate process (using hydrochlorofluorocarbon-123, HCFC-123) for expanding tobacco instead of the standard expansion process (using chlorofluorocarbon-11, CFC-11). Rats were exposed to smoke 1 hr/
Autor:
John W. Sagartz, Arnold T. Mosberg, Michael W. Ogden, A. Wallace Hayes, Christopher R. E. Coggins, Paul H. Ayres
Publikováno v:
Fundamental and Applied Toxicology
Sprague-Dawley rats were exposed 6 hr per day for 14 consecutive days to aged and diluted sidestream smoke (ADSS), used as a surrogate for Environmental Tobacco Smoke (ETS), at concentrations of 0.1 (typical), 1 (extreme), or 10 (exaggerated) mg of p
Autor:
CHRISTOPHER R. E. COGGINS, PAUL H. AYRES, ARNOLD T. MOSBERG, MICHAEL W. OGDEN, JOHN W. SAGARTZ, A. WALLACE HAYES
Publikováno v:
Toxicological Sciences. 19:133-140
Autor:
Mark A. Forsell, John W. Sagartz, Arpad J. Madarasz, Christopher R. E. Coggins, Paul H. Ayres, Gary T. Burger
Publikováno v:
Toxicologic Pathology. 20:118-121
In rodents, the larynx is a major site of histopathologic alteration following inhalation exposure to particulates, vapors, and aerosols. Specifically, the epithelial lining of a narrowly delineated region on the ventral floor of the larynges of rats
Autor:
James E. Swauger, W. Keith Shreve, Deborah H. Pence, John W. Sagartz, Ryan J. Potts, Daniel R. Meckley, Paul H. Ayres, David J. Doolittle
Publikováno v:
Inhalation toxicology. 19(8)
A subchronic, nose-only inhalation study was conducted to compare the effects of mainstream smoke from a reference cigarette containing conventional reconstituted tobacco sheet at 30% of the finished blend to mainstream smoke from cigarettes containi
Autor:
John W. Sagartz, Hugh M. Lovejoy, Christopher R. E. Coggins, W. Frederick McGuirt, A. Wallace Hayes, Paul H. Ayres
Publikováno v:
Toxicologic Pathology. 25:395-397
Parental smoking is a possible risk factor in the development of secretory otitis media (SOM) in children. This experiment was designed to determine, using rats as an experimental model, whether exposures to environmental tobacco smoke (ETS) produce
Publikováno v:
Inhalation toxicology. 13(2)
A subchronic, nose-only inhalation study comparing the potential biological activity of mainstream smoke from a cigarette that primarily heats tobacco (Eclipse) to mainstream smoke from a 1R4F reference cigarette was conducted using Sprague-Dawley ra