Zobrazeno 1 - 10
of 34
pro vyhledávání: '"John W. Russell"'
Publikováno v:
Annals of diagnostic pathology. 47
Mucosal Schwann cell hamartoma (MSCH) is an uncommon neural lesion characterized by an ill-defined proliferation of S100-positive Schwann cells in the lamina propria, with reported cases exclusively occurring in the colorectum. Here we describe the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6e762a8eda8b8d507a0f4e798a58fd
https://pubmed.ncbi.nlm.nih.gov/32460039
https://pubmed.ncbi.nlm.nih.gov/32460039
Autor:
Shuanghua Hu, Wendy Clarke, Yazhong Huang, John B. Hogan, Lawrence G. Iben, Graham S. Poindexter, Gail K. Mattson, Ling Chen, Guanglin Luo, John W. Russell, Ildiko Antal-Zimanyi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3814-3817
A convergent synthesis route for the heterocyclic modification of a novel bicyclo[3.1.0]hexane NPY1 antagonist 2 was developed and the structure activity relationship of these modifications on NPY1 binding is reported. Two heterocyclic analogs 9 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800f1807028db0439bba719aa1a01b3a
https://doi.org/10.1016/j.bmcl.2013.04.095
https://doi.org/10.1016/j.bmcl.2013.04.095
Publikováno v:
Swiss Journal of Geosciences. 101:1-15
The Lower Muschelkalk of N Switzerland is characterised by a relatively monotonous succession of marly and dolomitic limestones with siltstone layers and thin sandstone beds. The studied Leuggern, Weiach and Benken wells comprise completely cored sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e073c9d9dc9b5bb4cabcb511e5adab
https://doi.org/10.1007/s00015-007-1235-z
https://doi.org/10.1007/s00015-007-1235-z
Autor:
Marc Browning, John W. Russell, Astrid A. Ortiz, Gail K. Mattson, Sharon Flowers, Rachel T. McGovern, Mendi A. Higgins, Graham S. Poindexter, Wendy Clarke, Stefanie Rassnick, James E. Grace, John B. Hogan, Lawrence G. Iben, Ildiko Antal-Zimanyi, Kevin W. Gillman
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:5517-5526
A series of novel 5,5-diphenylimidazolones was synthesized and evaluated for activity against the human neuropeptide Y5 receptor. The 3-pyridyl analog 46 demonstrated an IC 50 of 8.3 nM with a favorable pharmacokinetic profile in rats, but was ineffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e01d7cffb040b3b57b8baf558bbd78
https://doi.org/10.1016/j.bmc.2006.04.042
https://doi.org/10.1016/j.bmc.2006.04.042
Autor:
Marco Dodier, Rebecca L. Drain, Alain Martel, Joanne J. Bronson, Kathleen W. Mosure, Patrice Gill, Stephan Roy, Terry M. Stickle, John W. Russell, Danielle Beaulieu, Cheryl Ferraro, Lawrence B. Snyder, Hyekyung Yang, Susan Chaniewski, Junius Clarke, Ken Denbleyker, Kenneth S. Santone, Stanley D'andrea, MaryBeth Frosco, Anne Marinier, Claude A. Quesnelle, Glen A. Warr, John F. Barrett, Jay O. Knipe, Dennis Taylor
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2728-2733
In an era of increasing resistance to classical antibacterial agents, the synthetic oxazolidinone series of antibiotics has attracted much interest. Zyvox™ was the first oxazolidinone to be approved for clinical use against infections caused by mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e23e62ba06a9197abb918ac020d2739
https://doi.org/10.1016/j.bmcl.2005.04.003
https://doi.org/10.1016/j.bmcl.2005.04.003
Autor:
Wright John J, Balu Balasubramanian, Ruediger Edward H, Stoffan Karen M, Craig R. Fairchild, Wendy Clarke, B. Narasimhulu Naidu, Carola Solomon, Milind Deshpande, Dolatrai M. Vyas, Byron H. Long, John W. Russell, Jeffrey Eummer, Kurt Zimmermann, David B. Frennesson, Henry Wong, William C. Rose, Frank Lee, Alain Martel, Francis Beaulieu, Robert Kramer, Mikael Mahler, Saulnier Mark G, Carol Bachand, Denis R. St. Laurent
Publikováno v:
Journal of Medicinal Chemistry. 47:1609-1612
A series of fluoroindolocarbazoles were studied with respect to their topoisomerase I activity, cytotoxicity, selectivity, and in vivo antitumor activity. Emerging from this series was BMS-251873, a potential clinical candidate possessing a robust ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8cbbd507cd3d0730a2f2eb53a2f4f7a
https://doi.org/10.1021/jm034197s
https://doi.org/10.1021/jm034197s
Autor:
Jeffrey L. Romine, Sally A Ward, Rachel T. McGovern, Ildiko Antal-Zimanyi, Wendy Clarke, John W. Russell, Scott W. Martin, Graham S. Poindexter, Sing-Yuen Sit, Mendi A. Higgins, Marc Bruce, J. Guy Breitenbucher
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:507-521
Structure–activity studies around the urea linkage in BMS-193885 ( 4a ) identified the cyanoguanidine moiety as an effective urea replacement in a series of dihydropyridine NPY Y 1 receptor antagonists. In comparison to urea 4a ( K i =3.3 nM), cyan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e218895db969aa14587cecdc250129
https://doi.org/10.1016/j.bmc.2003.10.016
https://doi.org/10.1016/j.bmc.2003.10.016
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 7:1787-1799
New avenues are reviewed and discussed for preventing industrial machine-related injury by means of realistic risk evaluation and reduction processes at the design and application stages of machinery development and use. U.S. guidelines and European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e1a23651ddcebc4baae8c23b8c99c14
https://doi.org/10.1080/20018091095393
https://doi.org/10.1080/20018091095393
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1945-1950
A series of cephalosporins bearing C-3 benzoyloxymethyl groups were prepared and evaluated for their anti-MRSA activity and plasma stability. They exhibit excellent in vitro activity (MIC = 0.06 ∼2 μg/mL) against MRSA and excellent stability in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64ebaf8ac4057403267f93d787e4b48d
https://doi.org/10.1016/s0960-894x(97)00338-7
https://doi.org/10.1016/s0960-894x(97)00338-7
Autor:
Nicholas A. Meanwell, John W. Russell, S. M. Seiler, Piyasena Hewawasam, Wright John J, J. A. Thomas, George B. Zavoico, M. Gamberdella, Harold Goldenberg
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103f8a58a40125a024c849951098e18c
https://doi.org/10.1002/chin.199411160
https://doi.org/10.1002/chin.199411160