Zobrazeno 1 - 10
of 151
pro vyhledávání: '"John W. Regan"'
Publikováno v:
FEBS Open Bio, Vol 12, Iss 4, Pp 775-783 (2022)
EP2 and EP4 prostanoid receptors have long been considered to have similar roles, since they are known to couple with Gαs‐protein and activate cAMP‐mediated signaling pathways. In this study, we re‐evaluated the results of cAMP assays with or
Externí odkaz:
https://doaj.org/article/a79c29d70feb4edab4f9c5e3620c8d8f
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 402-410 (2001)
Recent discoveries shed light on the importance of prostaglandin (PG) production in the development of skin cancer. Work by Fischer et al. demonstrates that skin tumor promotion caused by ultraviolet B radiation can be decreased by up to 89% by block
Externí odkaz:
https://doaj.org/article/df3a0253036e4e0c8dd0bb8e08d45de0
Autor:
Yutaka Tamura, John W. Regan, Keijo Fukushima, Toshihiko Murayama, Masato Mashimo, Akiko Suganami, Kanaho Senoo, Nanae Hasuoka, Iori Okura, Hiromichi Fujino
Publikováno v:
Pharmacological Reports. 73:946-953
Human DP and EP2 receptors are two of the most homologically related receptors coupling with Gαs-protein, which stimulate adenylyl cyclase to produce cAMP. Indeed, both receptors are considered to be generated by tandem duplication. It has been repo
Autor:
John W. Regan
Publikováno v:
Fire Technology. 57:1847-1867
When using solid fuels for live fire training,NFPA 1403: Standard on Live Fire Training Evolutionsrequires that the materials be wood based. While the standard offers guidance on the type of fuels that are permissible for use in training, it offers l
Autor:
Yutaka Tamura, Suzu Endo, Akiko Suganami, Keijo Fukushima, Yumi Araki, John W. Regan, Kanaho Senoo, Hiromichi Fujino, Masato Mashimo
Publikováno v:
Journal of Biological Chemistry. 295:13338-13352
Prostaglandin E2 (PGE2) is well-known as an endogenous proinflammatory prostanoid synthesized from arachidonic acid by the activation of cyclooxygenase-2. E type prostanoid (EP) receptors are cognates for PGE2 that have four main subtypes: EP1 to EP4
Autor:
Kana, Kitagawa, Ayaka, Hamaguchi, Keijo, Fukushima, Yuki, Nakano, John W, Regan, Masato, Mashimo, Hiromichi, Fujino
Publikováno v:
European journal of pharmacology. 920
Chronic inflammatory bowel disease (IBD), which is characterized by prolonged inflammation of the gastrointestinal tract is associated with an increased risk of colorectal cancer. Recent studies revealed that the pathology of IBD is caused by hyperac
Autor:
John W. Regan, Masato Mashimo, Keijo Fukushima, Takaya Misao, Toshihiko Murayama, Natsumi Tokashiki, Kana Kitagawa, Naoki Kurata, Hiromichi Fujino, Nanae Hasuoka
Publikováno v:
European Journal of Pharmacology. 853:308-315
Microbiota produce short chain fatty acids (SCFAs), which are known to maintain gut homeostasis, by the fermentation of dietary fiber in the human colon. Among SCFAs, butyrate has been considered as the most physiologically effective SCFA in colorect
Autor:
Iori, Okura, Nanae, Hasuoka, Kanaho, Senoo, Akiko, Suganami, Keijo, Fukushima, John W, Regan, Masato, Mashimo, Toshihiko, Murayama, Yutaka, Tamura, Hiromichi, Fujino
Publikováno v:
Pharmacological reports : PR. 73(3)
Human DP and EP2 receptors are two of the most homologically related receptors coupling with GFirst, we focused on the cAMP degradation pathways of DP and EP2 receptors stimulated by prostaglandin (PG) DWe found that PGDSince DP receptors and EP2 rec
Autor:
Suzu, Endo, Akiko, Suganami, Keijo, Fukushima, Kanaho, Senoo, Yumi, Araki, John W, Regan, Masato, Mashimo, Yutaka, Tamura, Hiromichi, Fujino
Publikováno v:
J Biol Chem
Prostaglandin E(2) (PGE(2)) is well-known as an endogenous proinflammatory prostanoid synthesized from arachidonic acid by the activation of cyclooxygenase-2. E type prostanoid (EP) receptors are cognates for PGE(2) that have four main subtypes: EP1
Autor:
Akito Onishi, Akiko Higashiyama, Shunya Yanagawa, Naofumi Seira, John W Regan, Kento Ohkawachi, Masaya Denda, Keijo Fukushima, Akira Otaka, Hiromichi Fujino
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1