Zobrazeno 1 - 9
of 9
pro vyhledávání: '"John W. Poutsiaka"'
Publikováno v:
Journal of International Medical Research. 1:489-503
During the course of drug development, there are many instances where extrapolation of data from animals to man is difficult because the toxicologic and metabolic responses induced by drugs may be significantly different between the laboratory specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3d66778e16ae9bfdfa9c909f341acc
https://doi.org/10.1177/030006057300100601
https://doi.org/10.1177/030006057300100601
Publikováno v:
Toxicology and Applied Pharmacology. 4:55-69
A simple method has been presented for the simultaneous determination of liver and kidney functions in dogs by the use of bromosulfalein (BSP) and phenolsulfonephthalein (PSP). A solution containing BSP and PSP was injected intravenously and the conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deed74c2db64b5e34ad91c1f3c9c05af
https://doi.org/10.1016/0041-008x(62)90076-5
https://doi.org/10.1016/0041-008x(62)90076-5
Publikováno v:
Experimental Biology and Medicine. 96:712-714
SummaryThe daily intramuscular administration of large doses (1 mg/kg) of nine-alpha-fluorohydrocortisone (FF) to intact dogs resulted in a chronic state of polydipsia and polyuria with gross evidence of mild dehydration. With FF treatment the fecal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b67e2aec72236b97f2f70f3fdefe493
https://doi.org/10.3181/00379727-96-23585
https://doi.org/10.3181/00379727-96-23585
Autor:
S. M. Singhvi, Eric C. Schreiber, Bernard F. Murphy, Louis T. DiFazio, John W. Poutsiaka, Anthony F. Heald
Publikováno v:
Toxicology and applied pharmacology. 43(1)
Disposition of [ 14 C]Nadolol in Dogs with Reversible Renal Impairment Induced by Uranyl Nitrate. Singhvi, S. M., Heald, A. F., Murphy, B. F., DiFazio, L. T., Schreiber, E. C., and Poutsiaka, J. W. (1978). Toxicol. Appl. Pharmacol. 43 , 99–109. A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94894e448a12db764ab06a9cadfc9e4c
https://pubmed.ncbi.nlm.nih.gov/24287
https://pubmed.ncbi.nlm.nih.gov/24287
Autor:
John W. Poutsiaka
Publikováno v:
The American journal of physiology. 185(3)
A simple and reliable method of extracting creatine from muscle for analysis as creatinine is described. In the absence of exogenous glycocyamine, growth was accelerated but muscle creatine levels were reduced in rats fed folacin and B12, either alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc54e339aeb32c3d957e46b6408deca
https://pubmed.ncbi.nlm.nih.gov/13339992
https://pubmed.ncbi.nlm.nih.gov/13339992
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 102
SummaryThe loss of potassium attending repeated administration of large doses of nine-alpha-fluorohydrocortisone (FF) to dogs depressed their glomerular filtration rate. In contrast, glomerular function showed a tendency to be augmented in a group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76477cf99c4aa6a6385ae50336302ae
https://pubmed.ncbi.nlm.nih.gov/14434531
https://pubmed.ncbi.nlm.nih.gov/14434531
Effects of benzydroflumethiazide (Naturetin) on the renal excretion of calcium and magnesium by dogs
Publikováno v:
Toxicology and applied pharmacology. 3
The intravenous administration of benzydroflumethiazide (BHFT) to dogs evoked marked increases in the renal excretion of sodium, enhanced much less the elimination of potassium, but had no significant effect on the excretion of calcium or magnesium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ef33bf05171079606cff8d52a48578
https://pubmed.ncbi.nlm.nih.gov/13737578
https://pubmed.ncbi.nlm.nih.gov/13737578
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 140(1)
SummaryIntravenous injections of SQ 20, 881, a competitive inhibitor of the angioten-sin-converting enzyme, suppressed the pressor and reduced renal blood flow responses initiated by the infusion of angiotensin I (50 to 100 ng/kg/min) into anesthetiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f72cb1f141f2571034c22ed72f71b8
https://pubmed.ncbi.nlm.nih.gov/4338182
https://pubmed.ncbi.nlm.nih.gov/4338182
Publikováno v:
Science (New York, N.Y.). 179(4073)
In single-dose parenteral studies with mice and dogs, the methyl ester hydrochloride of amphotericin B proved to be significantly less toxic than the parent compound, especially to the kidney.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740649bb4b116e3bbe225ef1f617382b
https://pubmed.ncbi.nlm.nih.gov/4686465
https://pubmed.ncbi.nlm.nih.gov/4686465