Zobrazeno 1 - 10
of 70
pro vyhledávání: '"John W. Mclean"'
Autor:
Jessica M. Froula, Benjamin W. Henderson, Jose Carlos Gonzalez, Jada H. Vaden, John W. Mclean, Yumei Wu, Gokulakrishna Banumurthy, Linda Overstreet-Wadiche, Jeremy H. Herskowitz, Laura A. Volpicelli-Daley
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Neuronal inclusions composed of α-synuclein (α-syn) characterize Parkinson’s Disease (PD) and Dementia with Lewy bodies (DLB). Cognitive dysfunction defines DLB, and up to 80% of PD patients develop dementia. α-Syn inclusions are abunda
Externí odkaz:
https://doaj.org/article/ba926feb28c449fa93eef0a3491c5679
Autor:
John W. McLean, Avnish Bhattrai, Francesca Vitali, Adam C. Raikes, Jean-Paul L. Wiegand, Roberta Diaz Brinton
Publikováno v:
Learning & Memory. 29:321-331
Age, genetics, and chromosomal sex have been identified as critical risk factors for late-onset Alzheimer's disease (LOAD). The predominant genetic risk factor for LOAD is the apolipoprotein E ε4 allele (APOE4), and the prevalence of LOAD is higher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a05175aea91b6e30f5e06cf684f6c476
https://doi.org/10.1101/lm.053588.122
https://doi.org/10.1101/lm.053588.122
Autor:
John W. McLean, Julie A. Wilson, Tina Tian, Jennifer A. Watson, Mary VanHart, Andrew J. Bean, Steven S. Scherer, David K. Crossman, Eroboghene Ubogu, Scott M. Wilson
Publikováno v:
J Neurosci
Endosomal sorting plays a fundamental role in directing neural development. By altering the temporal and spatial distribution of membrane receptors, endosomes regulate signaling pathways that control the differentiation and function of neural cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb129d750cf665d341f1b4bd2fdd090a
https://doi.org/10.1523/jneurosci.2481-21.2022
https://doi.org/10.1523/jneurosci.2481-21.2022
Translational potential of JAX humanized APOE mice: Metabolism and body composition in very old mice
Autor:
Avnish Bhattrai, John W. McLean, Adam C. Raikes, Jean‐Paul L. Wiegand, Stacy M Skopp, Roberta Diaz Brinton
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7dcc7c3bc4df800da2c5b93aa12293a
https://doi.org/10.1002/alz.068128
https://doi.org/10.1002/alz.068128
Autor:
John W. McLean, Elsa M. Reyes‐Reyes, Avnish Bhattrai, Jean‐Paul L. Wiegand, Adam C. Raikes, Kathleen E. Rodgers, Roberta Diaz Brinton
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff19ab3f75c93e95d570384206c292e8
https://doi.org/10.1002/alz.067815
https://doi.org/10.1002/alz.067815
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d32b5b85fd2e4b8fff3767a67ee57b
https://doi.org/10.1002/alz.068141
https://doi.org/10.1002/alz.068141
Publikováno v:
Journal of Neurochemistry. 148:386-399
Ubiquitin is an essential signaling protein that controls many different cellular processes. While cellular ubiquitin levels normally cycle between pools of free and conjugated ubiquitin, the balance of these ubiquitin pools can be shifted by exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261cc3b0de04d160b4ab7f263be113bd
https://doi.org/10.1111/jnc.14630
https://doi.org/10.1111/jnc.14630
Publikováno v:
J Neurochem
Strategies for enhancing protein degradation have been proposed for treating neurological diseases associated with a decline in proteasome activity. A proteasomal deubiquitinating enzyme that controls substrate entry into proteasomes, ubiquitin-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8bd5bfefbfcd8b0a7b7848736b4b82
https://pubmed.ncbi.nlm.nih.gov/32901953
https://pubmed.ncbi.nlm.nih.gov/32901953
Autor:
Jeremy H. Herskowitz, Benjamin W. Henderson, Jada H. Vaden, Laura A. Volpicelli-Daley, Gokulakrishna Banumurthy, Linda Overstreet-Wadiche, Yumei Wu, John W. Mclean, Jessica M. Froula, Jose Carlos Gonzalez
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-13 (2018)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Neuronal inclusions composed of α-synuclein (α-syn) characterize Parkinson’s Disease (PD) and Dementia with Lewy bodies (DLB). Cognitive dysfunction defines DLB, and up to 80% of PD patients develop dementia. α-Syn inclusions are abundant in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badac168f5f5beca278633e5fe7a1817
http://link.springer.com/article/10.1186/s40478-018-0537-x
http://link.springer.com/article/10.1186/s40478-018-0537-x
Autor:
John W. McLean
In this second volume, with numerous color photographs and diagrams, detailed techniques for making metaloceramic and alumina-reinforced crowns and bridges are presented. Special effects in dental procelain, the Wedge Technique, development of correc
