Zobrazeno 1 - 10
of 165
pro vyhledávání: '"John W. McBride"'
Autor:
Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Emma M. McErlean, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Publikováno v:
Cancer Nanotechnology, Vol 9, Iss 1, Pp 1-15 (2018)
Abstract Background Recent approvals of gene therapies by the FDA and the EMA for treatment of inherited disorders have further opened the door for assessment of nucleic acid pharmaceuticals for clinical usage. Arising from the presence of damaged or
Externí odkaz:
https://doaj.org/article/9ed2bf465afb41bba08a79b15b46f23a
Autor:
Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Ahlam A. Ali, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 249-258 (2017)
This study aimed to determine the therapeutic benefit of a nanoparticular formulation for the delivery of inducible nitric oxide synthase (iNOS) gene therapy in a model of breast cancer metastasis. Nanoparticles comprising a cationic peptide vector,
Externí odkaz:
https://doaj.org/article/6e5a1d3407dd4a3ab97c5e21c1d9b806
Autor:
Grace Cole, Joanne McCaffrey, Ahlam A. Ali, John W. McBride, Cian M. McCrudden, Eva M. Vincente-Perez, Ryan F. Donnelly, Helen O. McCarthy
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 1, Pp 50-62 (2017)
DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA
Externí odkaz:
https://doaj.org/article/34001c2764484bf090f282e497651d6e
Autor:
Thomas G. Bull, John W. McBride
Publikováno v:
Technologies, Vol 7, Iss 4, p 69 (2019)
Most failures in micro electromechanical system (MEMS) switches can be attributed to the degradation of contact surfaces and sticking contacts. A wear-tolerant composite contact material, composed of a Au film supported by multi walled carbon nanotub
Externí odkaz:
https://doaj.org/article/407e77fe62774610b201fa1e73a8ef8f
Autor:
Thomas G. Bull, John W. McBride
Publikováno v:
Technologies, Vol 6, Iss 2, p 47 (2018)
To develop robust microelectromechanical systems (MEMS) switching technology for low voltage direct current (DC) applications (1–12 V) there is a requirement for the investigation of wear caused by hot switching (contact operated while carrying a c
Externí odkaz:
https://doaj.org/article/9aa66c2a37674f4db204dfd4fdf04814
Autor:
Eoghan J. Mulholland, Monika Ziminska, Tracy Robson, Grace Cole, Vicky L. Kett, Helen O. McCarthy, Emma M. McErlean, Nicholas Dunne, Cian M. McCrudden, Niamh E. Buckley, John W. McBride, Stephen P. Loughran
Publikováno v:
McErlean, E M, Ziminska, M, McCrudden, C M, McBride, J W, Loughran, S P, Cole, G, Mulholland, E J, Kett, V, Buckley, N E, Robson, T, Dunne, N J & McCarthy, H O 2020, ' Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery ', Journal of Controlled Release, vol. 330, pp. 1288 . https://doi.org/10.1016/j.jconrel.2020.11.037
The design of a non-viral gene delivery system that can release a functional nucleic acid at the intracellular destination site is an exciting but also challenging proposition. The ideal gene delivery vector must be non-toxic, non-immunogenic, overco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f03a6e561e7b2be5887b475b411cf9e
https://doi.org/10.1016/j.jconrel.2020.11.037
https://doi.org/10.1016/j.jconrel.2020.11.037
Switching performance of a low-voltage switching device (LVSD) is determined by limiting current and stopping re-ignition. This is strongly influenced by how the arc moves inside the LVSD quenching chamber during the switching process. Improved switc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a153a8a747792d9277cc9e91c6350be
https://eprints.soton.ac.uk/450960/
https://eprints.soton.ac.uk/450960/
Autor:
Suhana Mohamed Sultan, Suan Hui Pu, Harold M. H. Chong, L.H. Wah, Sam Jeffery Fishlock, John W. McBride
Publikováno v:
2021 IEEE Regional Symposium on Micro and Nanoelectronics (RSM).
This work demonstrates the feasibility of fabricating resistive nanocrystalline graphite (NCG) on a Si substrate. The NCG film thickness of 9 nm was deposited using metal-free plasma enhanced chemical vapour deposition (PECVD) on a 6-inch p-type sili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b332e44edc938ee998bcee1b5daa9707
https://doi.org/10.1109/rsm52397.2021.9511601
https://doi.org/10.1109/rsm52397.2021.9511601
Natural human enamel (NHE) is a complex freeform surface which has presented significant difficulties in measuring surface form change using non-contacting laser profilometry (NCLP). Measuring surface form change on NHE is a metrology proxy for measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aea3cb8e90625424a057e6041bee935
https://eprints.soton.ac.uk/449545/
https://eprints.soton.ac.uk/449545/
Autor:
Sam Jeffery Fishlock, Suan Hui Pu, Yisong Han, Ting Yang Ling, Jamie D. Reynolds, Harold M. H. Chong, John W. McBride
Publikováno v:
IEEE Sensors Journal. 19:5421-5428
Environmental sensors play a crucial role in a wide range of applications. Among them, humidity sensors that are stable and operational in harsh environments are incredibly important for process control and monitoring. Nanocrystalline graphite (NCG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d36ae4936eaba1226778d910d1932
https://doi.org/10.1109/jsen.2019.2905719
https://doi.org/10.1109/jsen.2019.2905719