Zobrazeno 1 - 3
of 3
pro vyhledávání: '"John W. Maull"'
Autor:
Liang Jin, Fei Wang, Xue Wang, Bohdan P. Harvey, Yingtao Bi, Chenqi Hu, Baoliang Cui, Anhdao T. Darcy, John W. Maull, Ben R. Phillips, Youngjae Kim, Gary J. Jenkins, Thierry R. Sornasse, Yu Tian
Publikováno v:
Proteomes, Vol 11, Iss 4, p 32 (2023)
Rheumatoid arthritis (RA) is a systemic autoimmune and inflammatory disease. Plasma biomarkers are critical for understanding disease mechanisms, treatment effects, and diagnosis. Mass spectrometry-based proteomics is a powerful tool for unbiased bio
Externí odkaz:
https://doaj.org/article/aba8af6101fc46658bd818d60c99af6d
Autor:
Dan Shi, Moore Nigel St John, Donald B. Konopacki, Kelly J. Larson, Gary Gintant, Kathy K. Sarris, Peter F. Bousquet, Sean C. Turner, Peng Zhang, Ayome Abibi, Christopher M. Harris, Tegest Kebede, Xiubo Tang, Adrian D. Hobson, John W. Maull, Elizabeth Louise van der Kam, Ana L. Aguirre, Youngjae Kim, Anurupa Shrestha
Publikováno v:
Journal of Medicinal Chemistry. 58:9154-9170
S1P5 is one of 5 receptors for sphingosine-1-phosphate and is highly expressed on endothelial cells within the blood-brain barrier, where it maintains barrier integrity in in vitro models (J. Neuroinflamm. 2012, 9, 133). Little more is known about th
Autor:
Nathan S. Josephsohn, John W. Maull, Moore Nigel St John, Brian Bettencourt, Morytko Michael J, Lu Wang, Edit Tarcsa, Jonathan George, Biqin Li, Paul Rafferty, Diana L. Donnelly-Roberts, Marian T. Namovic, Patrick Betschmann, Michael Friedman, Jose-Andres Salmeron-Garcia, Gavin C. Hirst, Donald Konopacki, Woller Kevin R
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(14)
A novel series of cyanoguanidine-piperazine P2X(7) antagonists were identified and structure-activity relationship (SAR) studies described. Compounds were assayed for activity at human and rat P2X(7) receptors in addition to their ability to inhibit