Výsledky vyhledávání - "John W. Keyloun"

Akademický článek

Angiogenic gene characterization and vessel permeability of dermal microvascular endothelial cells isolated from burn hypertrophic scar

Autor: Esteban A. Molina, Brandon Hartmann, Mary A. Oliver, Liam D. Kirkpatrick, John W. Keyloun, Lauren T. Moffatt, Jeffrey W. Shupp, Taryn E. Travis, Bonnie C. Carney

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)

Abstract Hypertrophic scar (HTS) formation is a common challenge for patients after burn injury. Dermal microvascular endothelial cells (DMVECs) are an understudied cell type in HTS. An increase in angiogenesis and microvessel density can be observed

Externí odkaz: https://doaj.org/article/fb18cb3a91fa4afaa34a61a828ce4fde

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Trends in Traumatic Brain Injury Related to Consumer Products Among U.S. School-aged Children Between 2000 and 2019

Autor: Tuan D. Le, Alan D. Cook, Tony T. Le, John W. Keyloun, Paul W. Detwiler, Gerald R. Ledlow, Anthony E. Pusateri, Karan P. Singh

Publikováno v: American Journal of Preventive Medicine. 63:469-477

Consumer product‒related traumatic brain injury in children is common, but long-term trends have not been well characterized. Understanding the long-term trends in consumer product‒related traumatic brain injury may inform prevention efforts. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f3b858bbe558b983bad2a7dd7ebc02
https://doi.org/10.1016/j.amepre.2022.04.011

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Assessing Factor V Antigen and Degradation Products in Burn and Trauma Patients

Publikováno v: Journal of Surgical Research. 274:169-177

Proposed mechanisms of acute traumatic coagulopathy (ATC) include decreased clotting potential due to factor consumption and proteolytic inactivation of factor V (FV) and activated factor V (FVa) by activated protein C (aPC). The role of FV/FVa deple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ff2e87e7e5010732ea73826c3ec376
https://doi.org/10.1016/j.jss.2021.12.049

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Endothelial damage occurs early after inhalation injury as measured by increased syndecan-1 levels

Autor: Edward J Kelly, Bonnie C Carney, Mary A Oliver, John W Keyloun, Nicholas J Prindeze, Saira Nisar, Lauren T Moffatt, Jeffrey W Shupp

Publikováno v: Journal of Burn Care & Research.

Inhalation injury is a significant cause of morbidity and mortality in the burn patient population. However, the pathogenesis of inhalation injury and its potential involvement in burn shock is not well understood. Preclinical studies have shown endo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84dde64c840b780b2e6f2775b67d0604
https://doi.org/10.1093/jbcr/irad018

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Laser Treatment of Hypertrophic Scar in a Porcine Model Induces Change to Epidermal Histoarchitecture That Correlates to Improved Epidermal Barrier Function

Autor: Lesle M Jimenez, Mary A Oliver, John W Keyloun, Lauren T Moffatt, Taryn E Travis, Jeffrey W Shupp, Bonnie C Carney

Publikováno v: Journal of Burn Care & Research.

Mechanisms and timing of hypertrophic scar (HTS) improvement with laser therapy are incompletely understood. Epidermal keratinocytes influence HTS through paracrine signaling, yet they are understudied compared to fibroblasts. It was hypothesized tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b66b17b3ba3684cbcad2e9dcac8b96a
https://doi.org/10.1093/jbcr/irad010

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Early Transcriptomic Response to Burn Injury: Severe Burns Are Associated With Immune Pathway Shutdown

Autor: Marti Jett, John W Keyloun, Leanne Detwiler, Ruoting Yang, Ross Campbell, Stacy-Ann Miller, Aarti Gautam, Lauren T. Moffatt, Bonnie C. Carney, Jeffrey W. Shupp, Rasha Hammamieh

Publikováno v: J Burn Care Res

Burn injury induces a systemic hyperinflammatory response with detrimental side effects. Studies have described the biochemical changes induced by severe burns, but the transcriptome response is not well characterized. The goal of this work is to cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1982b7e58795bf24f8642d2e8a1e70da
https://doi.org/10.1093/jbcr/irab217

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A Pilot Study of Negative Pressure Therapy with Autologous Skin Cell Suspensions in a Porcine Model

Autor: Nicholas J. Prindeze, Saira Nisar, Taryn E Travis, Mary A. Oliver, Jeffrey W. Shupp, Liam D Kirkpatrick, John W Keyloun, Lauren T. Moffatt, Bonnie C. Carney

Publikováno v: Journal of Surgical Research. 267:182-196

Background Negative pressure wound therapy (NPWT) is an option for securing meshed split thickness skin grafts (mSTSGs) after burn excision to optimize skin graft adherence. Recently, the use of autologous skin cell suspension (ASCS) has been approve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb878466a10911eab52c00863fb22ac8
https://doi.org/10.1016/j.jss.2021.05.010

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Compounded Cerium Nitrate–Silver Sulfadiazine Cream is Safe and Effective for the Treatment of Burn Wounds: A Burn Center’s 4-Year Experience

Autor: John W Keyloun, Adam D Reese, Jeffrey W. Shupp, Taryn E Travis, Laura S. Johnson, Melissa M McLawhorn, Lauren T. Moffatt, Gaurav Garg

Publikováno v: Journal of Burn Care & Research. 43:716-721

Wound infections and sepsis are significant causes of morbidity after burn injury and can be alleviated by early excision and grafting. In situations that preclude early surgery, topical agents allow for a safer delay. Cerium nitrate compounded with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cc050bc8704b37ab1856ef8b94d04e2
https://doi.org/10.1093/jbcr/irab180

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COVID-19 infection and large intestinal perforation: A case series

Autor: Monika K. Masanam, Sarah M. Cheney, Whitney Sutton, John W. Keyloun, Shimae Fitzgibbons

Publikováno v: International journal of surgery case reports. 98

COVID-19 is a viral illness characterized primarily by respiratory symptoms. However, patients with COVID-19 infection may also present with gastrointestinal symptoms. Subsequent complications can be associated with high morbidity and mortality.This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051a485558835402e97a841e8ea29de0
https://pubmed.ncbi.nlm.nih.gov/36027834

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