Zobrazeno 1 - 10
of 167
pro vyhledávání: '"John W. Hadden"'
Autor:
Ronald G. Coffey, John W. Hadden
Publikováno v:
Stress, Immunity, and Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76d1b5a0d201dab1ae7dca1fb3940e6
https://doi.org/10.1201/9781003065180-22
https://doi.org/10.1201/9781003065180-22
Autor:
Wolf Herve Fridman, Harvey Brandwein, Neil L. Berinstein, J. Michael White, Cécile Badoual, James E. Egan, Lorraine Baltzer, Lynn C. Goldstein, Adel K. El-Naggar, Theresa L. Whiteside, John W. Hadden, Paul H. Naylor, Gregory T. Wolf
Publikováno v:
Cancer Immunology, Immunotherapy. 61:771-782
Twenty-seven subjects with squamous cell cancer of the head and neck received the neoadjuvant IRX-2 immunotherapy regimen prior to surgery in a Phase 2 trial. Pretreatment tumor biopsies were compared with the primary tumor surgical specimens for lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996dd8a7e44868cbd583f46433a9fa2c
https://doi.org/10.1007/s00262-011-1134-z
https://doi.org/10.1007/s00262-011-1134-z
Autor:
Jose Luis Barrera Franco, Lorraine Baltzer, Zygmund Roth, Daniel E. Kenady, Scott M. Freeman, Harvey Brandwein, John W. Hadden
Publikováno v:
American Journal of Clinical Oncology. 34:173-178
Objectives Head and neck squamous cell carcinoma (HNSCC) is associated with profound defects in cellular immunity. IRX-2, a primary cell-derived biologic containing multiple cytokines, has enhanced immune responses and induced tumor rejection in prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c0cf922e1b8a605262bcfd1873f25a
https://doi.org/10.1097/coc.0b013e3181dbb9d8
https://doi.org/10.1097/coc.0b013e3181dbb9d8
Autor:
Paul H. Naylor, John W. Hadden
Publikováno v:
Annals of the New York Academy of Sciences. 1194:162-168
Thymosin alpha1 (Talpha1) is a 28 amino acid biologically active protein with pleiotropic immune enhancing activity. IRX-2 is a primary cell-derived biologic containing multiple cytokines that enhance dendritic cell maturation, promote T-cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc919f13b81f06038b3d339449a1f4e1
https://doi.org/10.1111/j.1749-6632.2010.05475.x
https://doi.org/10.1111/j.1749-6632.2010.05475.x
Publikováno v:
Annals of the New York Academy of Sciences. 1112:235-244
Thymosin alpha1 (Talpha1) is a 28 amino acid biologically active protein cleaved from positions 2-29 of a precursor protein, prothymosin alpha. Since its discovery, Talpha1 has been administered to animals and humans in a wide variety of settings and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d32ebbc6305af2baa178d25e31d0fe
https://doi.org/10.1196/annals.1415.036
https://doi.org/10.1196/annals.1415.036
Publikováno v:
International Immunopharmacology. 3:1093-1104
Background : Hematological side effects are not generally expected due to radiotherapy involving limited radiation fields; however, patients with squamous cell carcinoma of the head and neck (SCCH&N) receiving radiation therapy frequently have chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1734eb587ae8d4707a2a0e5cfe588a6
https://doi.org/10.1016/s1567-5769(03)00013-4
https://doi.org/10.1016/s1567-5769(03)00013-4
Autor:
Jose Luis Barrera, Emma Verastegui, J de la Garza, Elba M. Hadden, Abelardo Meneses, Juan Zinser, John W. Hadden, M Kurman
Publikováno v:
International Immunopharmacology. 3:1073-1081
A Phase II trial in 42 patients with squamous cell cancer of the head and neck (H and NSCC) was performed using a combination immunotherapy with 10-20 days of perilymphatic injections of a natural cytokine mixture (NCM: IRX-2; 200 units IL-2 equivale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4623fccc6e2dc4428c7da8db590ff873
https://doi.org/10.1016/s1567-5769(03)00029-8
https://doi.org/10.1016/s1567-5769(03)00029-8
Autor:
John W. Hadden
Publikováno v:
International Immunopharmacology. 3:1061-1071
Cellular immunodeficiency is associated with human cancer. Extensive reviews on cancer of the head and neck, lung, esophagus and breast convince the author that for these diseases the immunodeficiency is reasonably well established yet the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3c6986e51ac62e590607a2af313180
https://doi.org/10.1016/s1567-5769(03)00060-2
https://doi.org/10.1016/s1567-5769(03)00060-2
Autor:
John W. Hadden, Kathy L. Signorelli
Publikováno v:
International Immunopharmacology. 3:1177-1186
Methyl inosine 5'-monophosphate (MIMP) was designed and synthesized in an endeavor to generate compounds with immunostimulatory activity based on the precedent of purines, particularly inosine playing a central role in the development and function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3918fce4624613a3271a0aca603a1f81
https://doi.org/10.1016/s1567-5769(03)00010-9
https://doi.org/10.1016/s1567-5769(03)00010-9