Zobrazeno 1 - 10
of 62
pro vyhledávání: '"John W. Donovan"'
Autor:
Federica Volpato, John W. Donovan, Monica Astolfi, Luisa Giaccone, Marco Ladetto, Benedetto Bruno, Selina Sametti, Antonio Palumbo, John G. Gribben, Fulvia Giaretta, Mario Boccadoro, Alessandro Pileri, Paola Omedè, Daniela Drandi
Publikováno v:
Experimental Hematology. 30:529-536
Objective Autologous transplantation of bone marrow (BM) and peripheral blood progenitor cells (PBPC) is commonly used for treatment of multiple myeloma (MM). Although both stem cell sources harbor residual clonal cells, a quantitative evaluation of
Autor:
Elizabeth G. Carideo, Peter W. Marks, Olivier Munoz, Donna Neuberg, Arnold S. Freedman, Peter O'Connell, Joachim L. Schultze, John W. Donovan, Hervé Husson, Antoinette Chillemi
Publikováno v:
Blood. 99:282-289
Follicular lymphomas (FLs) are neoplastic counterparts of normal germinal center (GC) B cells. FLs are characterized by t(14;18) with deregulation of the Bcl-2 (BCL2) gene. The presence of t(14;18) and overexpression of Bcl-2 is necessary, but not su
Autor:
John G. Gribben, G. Pierson, Jennifer S. Temel, Lisa Diller, Amy Zuckerman, Junjie Fang, Amy A. Ross, Stephan A. Grupp, John W. Donovan
Publikováno v:
Medical and Pediatric Oncology. 35:677-682
Background The suitability of CD34 selection for purging peripheral blood progenitor cells (PBPC) collected from patients with neuroblastoma (NB) has been called into question, largely because of reports of detection of low levels of CD34 on the surf
Publikováno v:
Journal of Molecular Medicine. 77:259-265
Detection of clonal tumor cells in leukemias and lymphomas by PCR in minimal residual disease (MRD) has been shown to be a valuable parameter for identifying patients who may require further treatment. Here we introduce the studies underway in our ow
Autor:
Niels S. Andersen, Christina Poor, John G. Gribben, Joseph S. Borus, Arnold S. Freedman, Lee M. Nadler, Jon C. Aster, John W. Donovan, Donna Neuberg
Publikováno v:
Blood. 90:4212-4221
To assess the clinical significance of minimal residual disease (MRD) detection by polymerase chain reaction (PCR) we analyzed samples from 26 patients with mantle cell lymphoma (MCL) who had undergone bone marrow transplantation (BMT) at the Dana-Fa
Autor:
G. Pierson, Amy Zuckerman, Lisa Diller, St. A. Grupp, S. Ash, Jennifer S. Temel, John W. Donovan, A. Ross, John G. Gribben, Junjie Fang
Publikováno v:
Transplantation in Hematology and Oncology II ISBN: 9783642626609
Purging of tumor cells from stem cell products used to support autologous transplant procedures to treat solid tumors may decrease the risk of relapse. Concerns have been raised about the use of the only widely available technique for stem cell purgi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b7bd8a89e0bd7e65a6432fa3fd251b
https://doi.org/10.1007/978-3-642-55774-3_15
https://doi.org/10.1007/978-3-642-55774-3_15
Autor:
Marco, Ladetto, Paola, Omedè, Selina, Sametti, John W, Donovan, Monica, Astolfi, Daniela, Drandi, Federica, Volpato, Luisa, Giaccone, Fulvia, Giaretta, Antonio, Palumbo, Benedetto, Bruno, Alessandro, Pileri, John G, Gribben, Mario, Boccadoro
Publikováno v:
Experimental hematology. 30(6)
Autologous transplantation of bone marrow (BM) and peripheral blood progenitor cells (PBPC) is commonly used for treatment of multiple myeloma (MM). Although both stem cell sources harbor residual clonal cells, a quantitative evaluation of their leve
Autor:
Manfred Mitterer, John G. Gribben, Alessandro Pileri, Dario Ferrero, Daniela Drandi, Corrado Tarella, John W. Donovan, P. Coser, Paolo Corradini, Selina Sametti, Irene Ricca, Monica Astolfi, Marco Ladetto
Objective Purging procedures are increasingly used to provide stem cell collections devoid of contaminating tumor cells. In follicle center lymphoma (FCL), most approaches eradicate polymerase chain reaction (PCR);–detectable disease in only a frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f03af9c6dee7b0986af6e41ca14813
http://hdl.handle.net/2318/36808
http://hdl.handle.net/2318/36808
Autor:
Marco Ladetto, Mathias Witzens, Robert H. Vonderheide, Joachim L. Schultze, Andreas Trojan, John G. Gribben, John W. Donovan
Although the idiotypic structures of immunoglobulin from malignant B cells were the first tumor-specific determinants recognized, and clinical vaccination trials have demonstrated induction of tumor-specific immunity, the function of immunoglobulin-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99b3d415589d5973cdc748154cdf9e9
http://hdl.handle.net/2318/40440
http://hdl.handle.net/2318/40440
Autor:
Andreas Trojan, John W. Donovan, Christina Poor, Sabine Harig, Edie Weller, Robert L. Schlossman, Marco Ladetto, Kenneth C. Anderson, John G. Gribben
The majority of patients with multiple myeloma (MM) have persistence of minimal residual disease (MRD), as determined by polymerase chain reaction (PCR) detection of clonal immunoglobulin H (IgH) gene rearrangements. As a result, PCR analysis has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50b54246e84a028b3ae74738c99d52f
http://hdl.handle.net/2318/40678
http://hdl.handle.net/2318/40678