Zobrazeno 1 - 10
of 214
pro vyhledávání: '"John W. Adamson"'
Autor:
Maxwell Chirehwa, Katya Govender, Kogieleum Naidoo, Sinaye Ncgapu, Paolo Denti, Ravesh Singh, John W. Adamson, Nonhlanhla Yende-Zuma, Helen McIlleron, Nesri Padayatchi, Anushka Naidoo, Veron Ramsuran
Publikováno v:
Pharmacogenomics. 20:225-240
Aim: We report the prevalence and effect of genetic variability on pharmacokinetic parameters of isoniazid and rifampicin. Materials & methods: Genotypes for SLCO1B1, NAT2, PXR, ABCB1 and UGT1A genes were determined using a TaqMan® Genotyping OpenAr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfef653446ab981495bcfe7cd449f518
https://doi.org/10.2217/pgs-2018-0166
https://doi.org/10.2217/pgs-2018-0166
Autor:
Iwuiji C, Richard A. Goldstein, John W. Adamson, de Oliveira T, Pillay D, Darren P. Martin, Derache A, Steven Kemp, Ravindra K. Gupta, Okesola N, Oscar Charles, François Dabis, Katya Govender
Viral population dynamics in long term viraemic antiretroviral therapy (ART) treated individuals have not been well characterised. Prolonged virologic failure on 2nd-line protease inhibitor (PI) based ART without emergence of major protease mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0027859d9b71ddbd2a936b231fd9d4
https://doi.org/10.1101/2021.04.09.21254592
https://doi.org/10.1101/2021.04.09.21254592
Autor:
Andreas Groll, Philippa C Matthews, Ken Sprenger, Nelisiwe Nxele, Bruce D. Walker, Nicholas Grayson, Photini Kiepiela, Julia Roider, Emily Adland, Krista L. Dong, Maria C. Puertas, Nisreen Khambati, Nomonde Bengu, Matthew J. Bull, David Bonsall, Thomas R. Connor, Katya Govender, Jane Millar, Rowena Fillis, John W. Adamson, Moherndran Archary, Vinicius A Vieira, Philip J. R. Goulder, Maximilian Muenchhoff, Nasreen Ismail, Thumbi Ndung'u, Vuyokazi Ntlantsana, Javier Martinez-Picado
Publikováno v:
EClinicalMedicine, Vol 22, Iss, Pp-(2020)
EClinicalMedicine
EClinicalMedicine
Background: Early combination antiretroviral therapy (cART) reduces the size of the viral reservoir in paediatric and adult HIV infection. Very early-treated children may have higher cure/remission potential. Methods: In an observational study of 151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d027f58ec77df9fc0ed584c0cb038c
https://ora.ox.ac.uk/objects/uuid:112d96f6-9c6c-4237-8e88-de8c60ac261a
https://ora.ox.ac.uk/objects/uuid:112d96f6-9c6c-4237-8e88-de8c60ac261a
Autor:
Andreas Groll, John C. Kappes, Constant Kapongo, Nomonde Bengu, Malini Krishna, Luisa Mori, John W. Adamson, Yeney Graza, Vuyokasi Ntlantsana, Christina Ochsenbauer, K Sprenger, Maximilian Muenchhoff, Marcus Altfeld, Jane Millar, Julia G. Prado, Philippa C Matthews, Julia Roider, Roopesh Bhoola, Moherndran Archary, Philip J. R. Goulder, Jeroen van Lobenstein, Mari C. Puertas, Vinicius A Vieira, Katya Govender, Marta Colomer Lluch, Neil McKerrow, Javier Martinez-Picado, Thumbi Ndung'u, Pieter Jooste, Kogielambal Chinniah, Nelisiwe Nxele, Emily Adland, Rowena Fillis, Ruth Penya Poderos
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Female children and adults typically generate more efficacious immune responses to vaccines and infections than age-matched males, but also suffer greater immunopathology and autoimmune disease. We here describe, in a cohort of > 170 in utero HIV-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586372f928adb3b14a1cbba47efd3729
http://europepmc.org/articles/PMC7156749
http://europepmc.org/articles/PMC7156749
Autor:
Bernadett I Gosnell, Rohen Harrichandparsad, Suzaan Marais, John W. Adamson, Khadija Khan, Gila Lustig, de Oliveira T, Yunus Moosa, Ravindra K. Gupta, Jennifer Giandhari, Alex Sigal, Yashica Ganga, Sandile Cele, Katya Govender, Patel, Farina Karim, Derache A
HIV persists despite antiretroviral therapy (ART) in cellular reservoirs thought to occur in distinct anatomical compartments. Therapy failure may occur because of incomplete ART adherence and possibly viral replication at some reservoir sites. The C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd99f46392d4ab535afa6afd3c98e625
https://doi.org/10.1101/588426
https://doi.org/10.1101/588426
Autor:
Sanil D. Singh, Chivonne Moodley, Jacques H. Grosset, Nicole C. Ammerman, Linda A. Bester, Zinhle Mgaga, Afton Dorasamy, Deepak V. Almeida, Rosemary V. Swanson, Sashen Moodley, Bongani Ngcobo, John W. Adamson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:2864-2869
Experimental and clinical studies have indicated that the antileprosy drug clofazimine may contribute treatment-shortening activity when included in tuberculosis treatment regimens. Clofazimine accumulates to high levels in tissues, has a long half-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8391438248db7f879560b0ca1c402d
https://doi.org/10.1128/aac.00177-16
https://doi.org/10.1128/aac.00177-16
Autor:
John C. Kappes, Nelisiwe Nxele, Katya Govender, M C Lluch, Philippa C Matthews, Mohendran Archary, C Kapongo, R P Poderos, John W. Adamson, Christina Ochsenbauer, Andreas Groll, Luisa Mori, Maximilian Muenchhoff, R Bhoola, Virgílio Vieira, K Sprenger, Vuyokazi Ntlantsana, J van Lobenstein, Jane Millar, Nomonde Bengu, Philip J. R. Goulder, M Krishna, Marcus Altfeld, Y Graza, Javier Martinez-Picado, K Chinniah, Julia G. Prado, Maria C. Puertas, Julia Roider, Rowena Fillis, Emily Adland, Thumbi Ndung'u, Neil McKerrow, Pieter Jooste
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Female children and adults typically generate more efficacious immune responses to vaccines and infections than age-matched males, but also suffer greater immunopathology and autoimmune disease. We here describe, in a cohort of 170 in utero HIV-infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82c1a6433e3e623a53a6f67783500cb
https://doaj.org/article/7527f99982aa4487840c21a50e1c8b3a
https://doaj.org/article/7527f99982aa4487840c21a50e1c8b3a
Autor:
Michael Auerbach, John W. Adamson
Publikováno v:
American Journal of Hematology. 91:31-38
It is estimated that one-third of the world's population is anemic, the majority being due to iron deficiency (ID). In adults, ID is associated with fatigue in the absence of anemia, restless legs syndrome, pica and, in neonates, delayed growth and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::827a597822717ecc17a9e681134c1366
https://doi.org/10.1002/ajh.24201
https://doi.org/10.1002/ajh.24201
Autor:
Chetan Seshadri, Zhongtao Wu, Mireia Coscolla, William R. Bishai, Sebastien Gagneux, Adriaan J. Minnaard, John W. Adamson, Richard Copin, Jeffrey Buter, Asa Tapley, Emilie Layre, David C. Young, Joel D. Ernst, Barry B. Snider, D. Branch Moody, Shih Jung Pan
Publikováno v:
Chemistry & biology, vol 22, iss 4
Chemistry & biology
Chemistry & biology, 2015, 22 (4), pp.516-526. ⟨10.1016/j.chembiol.2015.03.015⟩
Chemistry & Biology, 22(4), 516-526. CELL PRESS
Chemistry & biology
Chemistry & biology, 2015, 22 (4), pp.516-526. ⟨10.1016/j.chembiol.2015.03.015⟩
Chemistry & Biology, 22(4), 516-526. CELL PRESS
Although small molecules shed from pathogens are widely used to diagnose infection, such tests have not been widely implemented for tuberculosis. Here we show that the recently identified compound, 1-tuberculosinyladenosine (1-TbAd), accumulates to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94985921570803f39bc0ddde5efb6ae
https://doi.org/10.1016/j.chembiol.2015.03.015
https://doi.org/10.1016/j.chembiol.2015.03.015
Autor:
Kogieleum Naidoo, Nonhlanhla Yende-Zuma, Katya Govender, Nesri Padayatchi, Sabiha Y. Essack, Paolo Denti, Eddy Kimba-Phongi, John W. Adamson, Maxwell Chirehwa, Helen McIlleron, Anushka Naidoo
Publikováno v:
The Journal of antimicrobial chemotherapy. 72(5)
Objectives We compared the pharmacokinetics of moxifloxacin during rifampicin co-treatment or when dosed alone in African patients with drug-susceptible recurrent TB. Methods Patients in the intervention arm of the Improving Retreatment Success (IMPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae334cdda4b3b035e6fcf1a163e4ee8
https://pubmed.ncbi.nlm.nih.gov/28175315
https://pubmed.ncbi.nlm.nih.gov/28175315