Zobrazeno 1 - 10
of 47
pro vyhledávání: '"John W. Mace"'
Autor:
H Shahawy, Pål R. Njølstad, Andrew T. Hattersley, Richard E. Chinnock, Nathaniel K. Chan, Sian Ellard, Ricardo Peverini, John W. Mace, Eba Hathout, S Shahawy, E Young
Publikováno v:
Journal of Perinatology. 31:567-570
Permanent neonatal diabetes was previously assumed to require insulin injection or infusion for life. Recently, permanent neonatal diabetes resulting from mutations in the two protein subunits of the adenosine triphosphate-sensitive potassium channel
Autor:
Lawrence C. Sowers, Annie Tan, Ricardo Peverini, Naoaki Sakata, Richard E. Chinnock, Andre Obenaus, William J. Pearce, Nathaniel K. Chan, John W. Mace, Eba Hathout
Publikováno v:
Pediatric Transplantation. 13:892-897
Vascularization of transplanted islets must be maintained to provide long-term graft function. In vivo assessment of new vessel formation in islet grafts has been poorly documented. The purpose of this study was to investigate whether neovascularizat
Autor:
Naoki Sakata, Richard E. Chinnock, Andre Obenaus, John W. Mace, Eba Hathout, Nathaniel K. Chan
Publikováno v:
Islets. 1:26-33
BACKGROUND: Embolic occlusion of the portal vein due to islet transplantation is one of the major reasons for reduced survival of transplanted islets. In this study, we examined the location of islets as well as the correlation between islet and port
Efficacy Comparison Between Intraportal and Subcapsular Islet Transplants in a Murine Diabetic Model
Autor:
Lawrence C. Sowers, Annie Tan, Andre Obenaus, Naoaki Sakata, Nathaniel K. Chan, Ricardo Peverini, John W. Mace, Eba Hathout, Richard E. Chinnock
Publikováno v:
Transplantation Proceedings. 41:346-349
Background It is important to determine the efficacy of intraportal (IP) islet transplantation in comparison with other transplant sites. In this study, we sought to determine the optimal number of islets to achieve normoglycemia following transplant
Autor:
Annie Tan, Richard E. Chinnock, John W. Mace, Lawrence C. Sowers, Eba Hathout, Andre Obenaus, Ricardo Peverini, Rong Wang
Publikováno v:
Transplant International. 20:1059-1065
A main challenge for long-term insulin-independence following islet transplantation in type 1 diabetes is occult hypoxic, inflammatory, and immune graft loss [1-3]. Anoxia from initial avascularity is particularly stressful to islets function in the
Autor:
Andrew O. Hopper, Michael Kirby, Gang Miao, James Shapiro, Richard E. Chinnock, Ricardo Peverini, John W. Mace, Eba Hathout
Publikováno v:
Transplantation. 81:519-524
Background. Nerve growth factor (NGF) has been reported to play an important regulatory role in pancreatic beta-cell function. However, the usefulness of NGF in a transplantation setting is unknown. Methods. A marginal number of islet cells (260 isle
Autor:
John W. Mace, Eba Hathout, Shinichiro Maruo, Mariam Ischandar, Jonathan Geach, Leigh Fujishige
Publikováno v:
Diabetes Technology & Therapeutics. 5:801-806
To determine the effect of insulin glargine on glycemic control in pediatric type 1 and 2 diabetes, a retrospective repeated-measure analysis of variance was performed of hemoglobin A1C (HbA1C), frequency of hypoglycemia and hyperglycemia, mean blood
Autor:
Anna Rita Colacino, Jeannine Sharkey, Michael Racine, Sandra Nelsen-Cannarella, Omar R. Fagoaga, Noelle Hartwick, John W. Mace, Eba Hathout
Publikováno v:
Pediatrics. 111:860-863
Background. Little is known about auxologic, autoimmune, and HLA characteristics specific to children with early-onset diabetes (EOD). HLA subtypes have been shown to play an important part in the determination of islet-cell autoimmunity and in the p
Publikováno v:
Pediatric Diabetes. 3:184-188
OBJECTIVE To assess the role of ambient air pollutants in type 1 diabetes in children. DESIGN AND METHODS Prediagnosis exposure to five air pollutants was studied in two subgroups with onset of type 1 diabetes before and after 5 yr of age, and two ma
Autor:
Wendy Thomas, Jeannine Sharkey, Fadi Nahab, Michael Racine, Mohamed El-Shahawy, John W. Mace, Eba Hathout
Publikováno v:
Pediatric Diabetes. 1:131-134
The incidence of type 1 diabetes is increasing most rapidly in children under 5 yrs of age, a group where the disease appears to be more accelerated than traditional type 1 diabetes. Little is known about demographics, and markers of diabetes autoimm