Zobrazeno 1 - 10
of 130
pro vyhledávání: '"John W Swann"'
Autor:
Wu Chen, Zhao-Lin Cai, Eugene S Chao, Hongmei Chen, Colleen M Longley, Shuang Hao, Hsiao-Tuan Chao, Joo Hyun Kim, Jessica E Messier, Huda Y Zoghbi, Jianrong Tang, John W Swann, Mingshan Xue
Publikováno v:
eLife, Vol 9 (2020)
Mutations in genes encoding synaptic proteins cause many neurodevelopmental disorders, with the majority affecting postsynaptic apparatuses and much fewer in presynaptic proteins. Syntaxin-binding protein 1 (STXBP1, also known as MUNC18-1) is an esse
Externí odkaz:
https://doaj.org/article/5451bf743be645e0ad751bf6c73b334d
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 7 (2014)
The Pten and Tsc1 genes both encode proteins that repress mechanistic target of rapamycin (mTOR) signaling. Disruption of either gene in the brain results in epilepsy and autism-like symptoms in humans and mouse models, therefore it is important to u
Externí odkaz:
https://doaj.org/article/28d38b8c4e0742fab747fbb9dfe24627
Autor:
Melina L. Corriveau, Sabrina I. Amaya, Mary Clare Koebel, Vanesa C. Lerma, Sydney L. Michener, Alicia Turner, Rebecca J. Schultz, Elaine S. Seto, Gloria E. Diaz‐Medina, William J. Craigen, John W. Swann, Mingshan Xue, Hsiao‐Tuan Chao
Publikováno v:
American Journal of Medical Genetics Part A. 191:1619-1625
Neurobehavioral deficits and a progressive ictogenesis in the tetrodotoxin model of epileptic spasms
Publikováno v:
Epilepsia. 63:3078-3089
Our goal was to determine whether animals with a history of epileptic spasms have learning and memory deficits. We also used continuous (24/7) long-term electroencephalographic (EEG) recordings to evaluate the evolution of epileptiform activity in th
Autor:
Carlos J. Ballester‐Rosado, John T. Le, Trang T. Lam, Carrie A. Mohila, Sandi Lam, Anne E. Anderson, James D. Frost, John W. Swann
Publikováno v:
Annals of Neurology. 92:45-60
Publikováno v:
Epilepsia. 62:2263-2273
OBJECTIVE Epileptic spasms are a hallmark of a severe epileptic state. A previous study showed neocortical up and down states defined by unit activity play a role in the generation of spasms. However, recording unit activity is challenging in clinica
Autor:
Anthony A. Oliva, John W. Swann
Publikováno v:
BioTechniques, Vol 31, Iss 1, Pp 74-81 (2001)
Co-localization studies using green fluorescent protein (GFP) and fluorescence immunohistochemistry have become commonplace. However, co-localization studies using GFP and mRNA in situ hybridization are rare, in large part because typical in situ hyb
Externí odkaz:
https://doaj.org/article/def625fc5af64ae99e5ed8ca0ee09287
Publikováno v:
Epilepsy Behav
Studies were undertaken to evaluate the effectiveness of Acthar® Gel (repository corticotropin injection [RCI]) in the tetrodotoxin (TTX) model of early-life-induced epileptic spasms. Repository corticotropin injection (RCI) is widely used in the Un
Publikováno v:
Annals of neurology. 89(2)
Objective Epileptic spasms are a hallmark of severe seizure disorders. The neurophysiological mechanisms and the neuronal circuit(s) that generate these seizures are unresolved and are the focus of studies reported here. Methods In the tetrodotoxin m
Autor:
Eugene S. Chao, Colleen M Longley, Jianrong Tang, Zhao-Lin Cai, Huda Y. Zoghbi, Joo Hyun Kim, Jessica E Messier, Hongmei Chen, John W. Swann, Wu Chen, Hsiao-Tuan Chao, Shuang Hao, Mingshan Xue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709e676404f785c2be890fb2d3c688b7
https://doi.org/10.7554/elife.48705.sa2
https://doi.org/10.7554/elife.48705.sa2