Zobrazeno 1 - 10
of 160
pro vyhledávání: '"John W Kozarich"'
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172649 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0152934.].
Externí odkaz:
https://doaj.org/article/a8fee0abbac8433b9e3e6fd4953734b3
Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152934 (2016)
We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics. Matched normal and tumor colon samples were analyzed using an ATP acyl phosphate probe in a
Externí odkaz:
https://doaj.org/article/ffc6200c89354154984d306f8d950e36
Autor:
John W, Kozarich
Publikováno v:
Biochemistry. 60(46)
The founding of the journal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::217804cf565e5af7ca4755fa47f49e1d
https://pubmed.ncbi.nlm.nih.gov/34738805
https://pubmed.ncbi.nlm.nih.gov/34738805
Autor:
Tsuyoshi Imasaki, Patrick Baumann, Claudine Bisson, Ashish Radadiya, Yuichiro Takagi, David W. Rice, Svetlana E. Sedelnikova, Nigel G. J. Richards, Adriana Coricello, Tyzoon K. Nomanbhoy, Alexandria H. Berry, Sabine Wenzel, John W. Kozarich, Yi Jin, Brian E. Nordin, Wen Zhu, Francisco Martínez-Márquez
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-14 (2019)
Communications Biology
Communications Biology
Expression of human asparagine synthetase (ASNS) promotes metastatic progression and tumor cell invasiveness in colorectal and breast cancer, presumably by altering cellular levels of L-asparagine. Human ASNS is therefore emerging as a bona fide drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b6e17ac46e2600532640cbb5658656
http://link.springer.com/article/10.1038/s42003-019-0587-z
http://link.springer.com/article/10.1038/s42003-019-0587-z
Autor:
John W. Kozarich
Publikováno v:
Biochemistry. 60:3427-3428
The founding of the journal Biochemistry by the American Chemical Society 60 years ago was a highlight of the Society's growing commitment to chemically driven biochemistry. It was a commitment that was nearly an additional 60 years in the making. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fe89447fe91510790f48405ab3c5bf
https://doi.org/10.1021/acs.biochem.1c00569
https://doi.org/10.1021/acs.biochem.1c00569
Publikováno v:
BioTechniques, Vol 22, Iss 2, Pp 226-230 (1997)
Externí odkaz:
https://doaj.org/article/e6bde2b5d64d4541838e589689822e62
Autor:
Tyzoon K. Nomanbhoy, Sabine Wenzel, Alexandria H. Berry, Brian E. Nordin, Nigel G. J. Richards, Tsuyoshi Imasaki, David W. Rice, Claudine Bisson, Wen Zhu, Francisco Martínez-Márquez, Adriana Coricello, Patrick Baumann, Yuichiro Takagi, Ashish Radadiya, John W. Kozarich, Svetlana E. Sedelnikova, Yi Jin
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-1 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-1 (2019)
Expression of human asparagine synthetase (ASNS) promotes metastatic progression and tumor cell invasiveness in colorectal and breast cancer, presumably by altering cellular levels of L-asparagine. Human ASNS is therefore emerging as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7376b0d7f72c77cf8ba5e0a0098265f
https://doi.org/10.1038/s42003-019-0690-1
https://doi.org/10.1038/s42003-019-0690-1
Autor:
Kevin B. Dagbay, Tyzoon K. Nomanbhoy, John W. Kozarich, Jennifer L. Green, Eric Okerberg, Sergey N. Savinov, Ishankumar V Soni, Arwin Aban, Jeanne A. Hardy
Publikováno v:
Biochemistry. 58(52)
Acyl phosphates of ATP (ATPAc) and related nucleotides have proven to be useful for the interrogation of known nucleotide binding sites via specific acylation of conserved lysines (K). In addition, occasional K acylations are identified in proteins w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9951abe25ba37f1bc861f527af08a296
https://pubmed.ncbi.nlm.nih.gov/31095371
https://pubmed.ncbi.nlm.nih.gov/31095371
Autor:
Senait Alemayehu, Jonathan S. Rosenblum, Geeta Sharma, Tyzoon K. Nomanbhoy, Arwin Aban, Maria Sykes, John W. Kozarich, Subha Vogeti, Jiangyue Wu, Heidi E. Brown
Publikováno v:
Biochemistry. 55:5434-5441
Palbociclib is a cyclin-dependent kinase (CDK) 4/CDK6 inhibitor approved for breast cancer that is estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative. We profiled palbociclib in cells either sensitive or resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0fa0d0cdcae66e49708ed45db5efd4
https://doi.org/10.1021/acs.biochem.6b00629
https://doi.org/10.1021/acs.biochem.6b00629
Autor:
Wen Zhu, Brian E. Nordin, John W. Kozarich, David W. Rice, Yi Jin, Svetlana E. Sedelnikova, Nigel G. J. Richards, Yuichiro Takagi, Sabine Wenzel, Claudine Bisson, Ashish Radadiya, Alexandria H. Berry, Patrick Baumann, Tsuyoshi Imasaki, Tyzoon K. Nomanbhoy
Expression of the enzyme human asparagine synthetase (ASNS) promotes metastatic progression in breast cancer, which affects L-asparagine levels and tumor cell invasiveness. Human ASNS has therefore emerged as abona fidedrug target for cancer therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278fe1ec095c7d5883329324ce978eb5
