Impact of the Cornea Donor Study on Acceptance of Corneas From Older Donors

Autor: Bradley Tennant, Monty M. Montoya, John W. Cowden, Alan Sugar, Mark J. Mannis, Jackie Malling, Roy W. Beck, Robin L. Gal, Mariya Dontchev, Craig Kollman

Publikováno v: Cornea. 31:1441-1445

PURPOSE To evaluate retrospectively whether the findings from the Cornea Donor Study (CDS) led to changes in the transplantation of corneas from older donors. METHODS Eye banks in United States provided complete data on donor age and placement (domes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a5c1f0bba8bf8c83afaa5f7a7411a6
https://doi.org/10.1097/ico.0b013e31823f7550

Polyethylenimine-conjugated gold nanoparticles: Gene transfer potential and low toxicity in the cornea

Autor: Rangan Gupta, John W. Cowden, Alexander M. Klibanov, J. David Robertson, Rajiv R. Mohan, Ashish Tandon, Jonathan C.K. Tovey, Frank G. Rieger, Ajay Sharma, Jennifer A. Fortune

Publikováno v: PMC

This study examined the gene transfer efficiency and toxicity of 2-kDa polyethylenimine conjugated to gold nanoparticles (PEI2-GNPs) in the human cornea in vitro and rabbit cornea in vivo. PEI2-GNPs with nitrogen-to-phosphorus ratios of up to 180 exh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12efa807537d854abb20209504174765
https://doi.org/10.1016/j.nano.2011.01.006

Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo

Autor: J. C. K. Tovey, Gregory S. Schultz, Ashish Tandon, John W. Cowden, Rajiv R. Mohan, Ajay Sharma

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e26432 (2011)

Decorin, small leucine-rich proteoglycan, has been shown to modulate angiogenesis in nonocular tissues. This study tested a hypothesis that tissue-selective targeted decorin gene therapy delivered to the rabbit stroma with adeno-associated virus sero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de72b4c4a5b2d23fae67220d70a2d5d
https://pubmed.ncbi.nlm.nih.gov/22039486

Contributors

Autor: Richard L Abbott, Sean D Adrean, Abdulrahman Al-Muammar, Jihan Akhtar, Eduardo C Alfonso, Richard C Allen, M Camille Almond, Lênio Alvarenga, Wallace LM Alward, Renato Ambrósio, Mohammad Anwar, Dimitri T Azar, James L Ball, Neal P Barney, Rebecca M Bartow, Jules Baum, Michael W Belin, Jason H Bell, Beth Ann Benetz, Zachary Berbos, Roger W Beuerman, Arpita Kadakia Bhasin, Pooja V Bhat, Joseph M Biber, Maria Bidros, Andrea D Birnbaum, Charles S Bouchard, Jay C Bradley, James D Brandt, Richard D Brasington, Harilaos S Brilakis, Cat N Burkat, Marta Calatayud, J Douglas Cameron, Mauro Campos, Emmett F Carpel, H Dwight Cavanagh, Cordelia Chan, Richard I Chang, Bernard H Chang, Kenneth C Chern, Steven Ching, James Chodosh, Phillip H Choo, Gary Chung, Joseph B Ciolino, Janine A Clayton, Elisabeth J Cohen, Oliver Comyn, M Soledad Cortina, John W Cowden, Christopher R Croasdale, Richard S Davidson, Elizabeth A Davis, Sheraz M Daya, Denise de Freitas, David L DeMill, Lauro Augusto de Oliveira, Marc D de Smet, Luciene B de Sousa, Ali R Djalilian, Claes H Dohlman, Eric D Donnenfeld, Richard K Dortzbach, William T Driebe, Steven P Dunn, Ralph C Eagle, Sean L Edelstein, Richard A Eiferman, Joseph A Eliason, Marjan Farid, William J Faulkner, Robert S Feder, Vahid Feiz, Matthew T Feng, John H Fingert, George J Florakis, Luigi Fontana, Richard K Forster, C Stephen Foster, F Stuart Foster, Gary N Foulks, Mitchell H Friedlander, Masahiko Fukuda, Anat Galor, Theresa J Gan, Prashant Garg, Sumit Garg, David B Glasser, Kenneth M Goins, Debra A Goldstein, Chloe Gottlieb, Michael R Grimmett, Oscar Gris, Erich B Groos, William D Gruzensky, Jose L Güell, Preeya K Gupta, M Bowes Hamill, Kristin M Hammersmith, Pedram Hamrah, Sadeer B Hannush, David R Hardten, Andrew Harrison, Ellen L Heck, David G Heidemann, David C Herman, J Martin Heur, William G Hodge, Carol J Hoffman, Edward J Holland, Gary N Holland, Marc A Honig, Christopher T Hood, Eliza N Hoskins, Andrew J W Huang, David Huang, Jennifer I Hui, Joseph D Iuorno, W Bruce Jackson, Frederick A Jakobiec, Bennie H Jeng, James V Jester, David R Jordan, Terry L Kaiura, Carol L Karp, Douglas G Katz, Stephen C Kaufman, Robert C Kersten, Stephen S Khachikian, Jennifer H Kim, Joung Y Kim, Stella K Kim, Terry Kim, Colin M Kirkness, Stephen D Klyce, Douglas D Koch, Regis P Kowalski, Jay H Krachmer, Peter R Laibson, Stephen S Lane, Jonathan H Lass, W Barry Lee, Olivia A Lee, Michael A Lemp, Phoebe D Lenhart, Yan Li, Thomas J Liesegang, Michele C Lim, Lily Koo Lin, Michael P Lin, Thomas D Lindquist, Richard L Lindstrom, David Litoff, Christopher Liu, Careen Y Lowder, Anthony J Lubniewski, Hall T McGee, Ian W McLean, Marian S Macsai, Felicidad Manero, Mark J Mannis, Dimosthenis Mantopoulos, Carlos E Martinez, Csaba L Mártonyi, Raneen S Mashor, William D Mathers, Manisha N Mehta, David M Meisler, Shahzad I Mian, Darlene Miller, Corey A Miller, Monty Montoya, Merce Morral, Andrew L Moyes, Michael L Murphy, Nariman Nassiri, Kristiana D Neff, J Daniel Nelson, Jeffrey A Nerad, Marcelo V Netto, Christopher J Newton, Lisa M Nijm, Teruo Nishida, Bruce A Noble, Michael L Nordlund, Robert B Nussenblatt, David G O'Day, Jenny V Ongkosuwito, Karen W Oxford, David A Palay, Florentino E Palmon, Deval R Paranjpe, Mansi Parikh, David H Park, D J John Park, Matthew R Parsons, Charles J Pavlin, Eric S Pearlstein, Alicia Perry, W Matthew Petroll, Daryl R Pfister, Roswell R Pfister, Stephen C Pflugfelder, Francis W Price, Marianne O Price, Louis E Probst, John J Purcell, Andrew A E Pyott, Michael B Raizman, Leela V Raju, J Bradley Randleman, Gullapalli N Rao, Christopher J Rapuano, Charles D Reilly, Adimara de Candelaria Renesto, Renata A Rezende, Danielle M Robertson, David S Rootman, Jason S Rothman, Roy Scott Rubinfeld, Alan E Sadowsky, Shizuya Saika, Monali V Sakhalkar, James J Salz, Virender S Sangwan, Marinho Scarpi, Bradley H Scharf, Greg Schmidt, Artur Schmitt, Fernanda Piccoli Schmitt, Miriam T Schteingart, Ivan R Schwab, Brian L Schwam, Gary S Schwartz, H Nida Sen, Michael B Shapiro, Shigeto Shimmura, Neera Singal, Heather M Skeens, Craig A Skolnick, Allan R Slomovic, Janine A Smith, Michael E Snyder, Renée Solomon, Sarkis H Soukiasian, Sathish Srinivasan, John F Stamler, Roger F Steinert, Glenn L Stoller, Barbara W Streeten, R Doyle Stulting, Alan Sugar, Joel Sugar, Donald Tan, Joseph Tauber, Mark A Terry, Howard H Tessler, Marta Torrabadella, Elias I Traboulsi, William B Trattler, Julie H Tsai, David T Tse, Elmer Y Tu, Roxana Ursea, Pravin K Vaddavalli, Woodford S Van Meter, Gary A Varley, Roshni Vasaiwala, Anthony J Verachtert, David D Verdier, Ana Carolina Vieira, Vanee V Virasch, Li Wang, George O Waring, Michael A Warner, Kevin J Warrian, Guy F Webster, Mitchell P Weikert, Robert W Weisenthal, Jayne S Weiss, Pongmas Wichiensin, Kirk R Wilhelmus, Steven E Wilson, Maria A Woodward, Richard W Yee, Sonya Yoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4b98029da83cc92c271fdbbe3702508
https://doi.org/10.1016/b978-0-323-06387-6.00005-2

Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblasts

Autor: Sunilima Sinha, Rajiv R. Mohan, Rangan Gupta, Maneesh K. Mehan, John W. Cowden

Decorin, a small leucine-rich proteoglycan, is a natural inhibitor of transforming growth factor beta (TGFbeta). Myofibroblast and haze formation in the cornea have been attributed to TGFbeta hyperactivity released from corneal epithelium following i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33035b772a2019e1f6c64187f0c6421b
https://europepmc.org/articles/PMC2929567/