Zobrazeno 1 - 10
of 320
pro vyhledávání: '"John W Barrett"'
Autor:
Nicole Pinto, Stephenie D Prokopec, Farhad Ghasemi, Jalna Meens, Kara M Ruicci, Imran M Khan, Neil Mundi, Krupal Patel, Myung W Han, John Yoo, Kevin Fung, Danielle MacNeil, Joe S Mymryk, Alessandro Datti, John W Barrett, Paul C Boutros, Laurie Ailles, Anthony C Nichols
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239315 (2020)
Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that is typically resistant to chemotherapy and radiation. Alternative strategies to target this cancer at a molecular level are necessary in order to improve dismal outcom
Externí odkaz:
https://doaj.org/article/2624fda7a2a3436c9e175b48f7153684
Autor:
Nicole Pinto, Stephenie D Prokopec, Frederick Vizeacoumar, Karlee Searle, Matthew Lowerison, Kara M Ruicci, John Yoo, Kevin Fung, Danielle MacNeil, Jim C Lacefield, Hon S Leong, Joe S Mymryk, John W Barrett, Alessandro Datti, Paul C Boutros, Anthony C Nichols
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207152 (2018)
Anaplastic thyroid cancer (ATC) is a rare and lethal human malignancy with no known effective therapies in the majority of cases. Despite the use of conventional treatments such as chemotherapy, radiation and surgical resection, this disease remains
Externí odkaz:
https://doaj.org/article/791914e6779c49f59f8e351657650e5c
Autor:
Jessica G Tong, Yudith Ramos Valdes, John W Barrett, John C Bell, David Stojdl, Grant McFadden, J Andrea McCart, Gabriel E DiMattia, Trevor G Shepherd
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissemination of malignant cells traversing throughout the intraperitoneal fluid. Accordingly, we test new therapeutic strategies using an in vitro three-di
Externí odkaz:
https://doaj.org/article/c244a8fac6094fe2bac70100a0881479
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003411 (2013)
Upon infection, human adenovirus (HAdV) must activate the expression of its early genes to reprogram the cellular environment to support virus replication. This activation is orchestrated in large part by the first HAdV gene expressed during infectio
Externí odkaz:
https://doaj.org/article/0f95c95895334819a3086eb8c23e9d38
Autor:
Fuan Wang, Xiujuan Gao, John W Barrett, Qing Shao, Eric Bartee, Mohamed R Mohamed, Masmudur Rahman, Steve Werden, Timothy Irvine, Jingxin Cao, Gregory A Dekaban, Grant McFadden
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000099 (2008)
The sensing of pathogen infection and subsequent triggering of innate immunity are key to controlling zoonotic infections. Myxoma virus (MV) is a cytoplasmic DNA poxvirus that in nature infects only rabbits. Our previous studies have shown that MV in
Externí odkaz:
https://doaj.org/article/d77359388584476e97434023914dd5ba
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Autor:
Corby Fink, Julia J. Gevaert, John W. Barrett, Jimmy D. Dikeakos, Paula J. Foster, Gregory A. Dekaban
Publikováno v:
European Radiology Experimental, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Background Despite widespread study of dendritic cell (DC)-based cancer immunotherapies, the in vivo postinjection fate of DC remains largely unknown. Due in part to a lack of quantifiable imaging modalities, this is troubling as the amount
Externí odkaz:
https://doaj.org/article/1efb13964c7743ad84a46c760b57440c
Autor:
Steven F. Gameiro, Mikhail Y. Salnikov, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
Viruses, Vol 15, Iss 12, p 2411 (2023)
Human papillomavirus (HPV) is the major causative agent for cervical and many head and neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that may become established via positive selection. Within an HPV type, viral iso
Externí odkaz:
https://doaj.org/article/8cdc15fdb1154c088967c5e89ad98748
Autor:
Mikhail Salnikov, Steven F. Gameiro, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT Human papillomaviruses (HPVs) are highly infectious and cause the most common sexually transmitted viral infections. They induce hyperproliferation of squamous epithelial tissue, often forming warts. Virally encoded proteins reprogram gene e
Externí odkaz:
https://doaj.org/article/2657d1b773dc485f89420a45ebcca125
Autor:
Naif Fnais, Francisco Laxague, Faisal Alzahrani, Kevin Fung, Eric Di Gravio, Danielle MacNeil, Adrian Mendez, John Yoo, Pencilla Lang, Joe S. Mymryk, John W. Barrett, Keng Yow Tay, Andrew Leung, Anthony C. Nichols, David A. Palma
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 113:521-529
Primary radiation therapy with or without chemotherapy (RT/CRT) is the most common treatment for oropharyngeal squamous cell carcinomas (OPSCC), but there has been an increase in transoral surgery (TOS) for T1-2 tumors. Because only a subset of T1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644023c15227006a421878081b785855
https://doi.org/10.1016/j.ijrobp.2022.02.025
https://doi.org/10.1016/j.ijrobp.2022.02.025