Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John W Balliet"'
Autor:
James M Wagner, J David Pajerowski, Christopher L Daniels, Patrick M McHugh, Jessica A Flynn, John W Balliet, Danilo R Casimiro, Shyamsundar Subramanian
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94401 (2014)
Chikungunya virus-like particles (VLPs) have potential to be used as a prophylactic vaccine based on testing in multiple animal models and are currently being evaluated for human use in a Phase I clinical trial. The current method for producing these
Externí odkaz:
https://doaj.org/article/de84d5cc23ff4b7a97129b9a9cf8fabb
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101373 (2014)
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response. Importantly, CJ2-gD2 expresses g
Externí odkaz:
https://doaj.org/article/d58c00fe094848339728088feb4a8a7a
Autor:
Jennifer Galli, Maya Salnikova, Michael Cai, John W. Balliet, Sandra Rios, Robert C. Davidson, Danilo R. Casimiro, Sita Awasthi, Harvey M. Friedman, Martha Brown, John M. Lubinski, Carolyn E. Shaw, Ryan Swoyer, Judith F. Smith, Susan Kingsley, Rose Kowalski, Janine T. Bryan, Daniel J. DiStefano, Victoria Copeland, Jessica A. Flynn
Publikováno v:
Journal of Virology. 88:2000-2010
A prophylactic vaccine for genital herpes disease remains an elusive goal. We report the results of two studies performed collaboratively in different laboratories that assessed immunogenicity and vaccine efficacy in herpes simplex virus 1 (HSV-1)-se
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e101373 (2014)
PLoS ONE, Vol 9, Iss 6, p e101373 (2014)
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response. Importantly, CJ2-gD2 expresses g
Publikováno v:
Journal of Virology. 74:3731-3739
Short hydrophobic regions referred to as fusion peptide domains (FPDs) at or near the amino terminus of the membrane-anchoring subunit of viral glycoproteins are believed to insert into the host membrane during the initial stage of enveloped viral en
Autor:
John W. Balliet, Paul Bates
Publikováno v:
Europe PubMed Central
Many host cell surface proteins, including viral receptors, are incorporated into enveloped viruses. To address the functional significance of these host proteins, murine leukemia viruses containing the cellular receptors for Rous sarcoma virus (Tva)
Autor:
John W. Balliet, Christine Debouck, Ronald G. Collman, Renee Hrin, Mark A. Laughlin, Francisco Gonzalez-Scarano, Kathleen A. McGann, Dennis L. Kolson
Publikováno v:
Journal of General Virology. 75:1927-1934
Neurological dysfunction in AIDS occurs in the absence of productive infection of neurons, and may involve modulation of neuronal cell function by viral or cellular products released from surrounding infected cells. The human immunodeficiency virus t
Autor:
Janine T. Bryan, Susan Kingsley, Fushan Wang, Jessica A. Flynn, John W. Balliet, John M. Lubinski, Daniel J. DiStefano, Carolyn E. Shaw, Harvey M. Friedman, Michael Cai, Michael R. Betts, Sita Awasthi, Danilo R. Casimiro, Shana M. Barrett
Attempts to develop a vaccine to prevent genital herpes simplex virus 2 (HSV-2) disease have been only marginally successful, suggesting that novel strategies are needed. Immunization with HSV-2 glycoprotein C (gC-2) and gD-2 was evaluated in mice an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c78e738cd076759731dba450c8c7a58
https://europepmc.org/articles/PMC3187515/
https://europepmc.org/articles/PMC3187515/
A recombinant HSV-1 virus expressing EGFP from the HCMV major immediate early promoter (KOS-CMVGFP) was constructed to monitor viral replication and spread in vitro and in mice. KOS-CMVGFP replicated as efficiently as wild-type virus, strain KOS, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e1f998f96f5cb8daccbdc52caa2037
https://europepmc.org/articles/PMC1975764/
https://europepmc.org/articles/PMC1975764/
Autor:
Magdalena Kosz-Vnenchak, David M. Knipe, Todd L. Astor, Joseph S. Orlando, Anna S. Kushnir, Stephen A. Rice, Priscilla A. Schaffer, John W. Balliet
Publikováno v:
Journal of virology. 80(19)
The immediate-early regulatory protein ICP22 is required for efficient replication of herpes simplex virus type 1 in some cell types (permissive) but not in others (restrictive). In mice infected via the ocular route, the pathogenesis of an ICP22 −