Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John W Annand"'
Autor:
Marek J Kobylarz, Jonathan M Goodwin, Zhao B Kang, John W Annand, Sarah Hevi, Ellen O'Mahony, Gregory McAllister, John Reece-Hoyes, Qiong Wang, John Alford, Carsten Russ, Alicia Lindeman, Martin Beibel, Guglielmo Roma, Walter Carbone, Judith Knehr, Joseph Loureiro, Christophe Antczak, Dmitri Wiederschain, Leon O Murphy, Suchithra Menon, Beat Nyfeler
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0235551 (2020)
VPS34 is a key regulator of endomembrane dynamics and cargo trafficking, and is essential in cultured cell lines and in mice. To better characterize the role of VPS34 in cell growth, we performed unbiased cell line profiling studies with the selectiv
Externí odkaz:
https://doaj.org/article/405ec165a99f440886a38bc379ff0399
Autor:
Amanda J Martinot, Mary Farrow, Lu Bai, Emilie Layre, Tan-Yun Cheng, Jennifer H Tsai, Jahangir Iqbal, John W Annand, Zuri A Sullivan, M Mahmood Hussain, James Sacchettini, D Branch Moody, Jessica C Seeliger, Eric J Rubin
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005351 (2016)
Mycobacterium tuberculosis (Mtb) mutants lacking rv1411c, which encodes the lipoprotein LprG, and rv1410c, which encodes a putative efflux pump, are dramatically attenuated for growth in mice. Here we show that loss of LprG-Rv1410 in Mtb leads to int
Externí odkaz:
https://doaj.org/article/3122182a17664a31b85cc45e21e4b8b4
Autor:
Andrew C. Tolonen, Nadine Fornelos, John W. Annand, Ashley L. Garner, R. Balfour Sartor, Jason Bishai, Hera Vlamakis, Eric A. Franzosa, Clary B. Clish, Jeffrey A. Porter, Julian Avila-Pacheco, Henry J. Haiser, Akihiko Oka, Curtis Huttenhower, Timothy D. Arthur, Jason Lloyd-Price, Ramnik J. Xavier
Publikováno v:
Nature microbiology
Inflammatory bowel diseases (IBD) are associated with alterations in gut microbial abundances and lumenal metabolite concentrations, but the effects of specific metabolites on the gut microbiota in health and disease remain largely unknown. Here, we
Autor:
Jeffrey Buter, Eric J. Rubin, Amanda J. Martinot, Sarah M. Fortune, Ho Jun Lee, David C. Young, Tom Alber, Barry B. Snider, Adriaan J. Minnaard, John W. Annand, Emilie Layre, Isamu Matsunaga, D. Branch Moody
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 111(8), 2978-2983. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (8), pp.2978-2983. ⟨10.1073/pnas.1315883111⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (8), pp.2978-2983. ⟨10.1073/pnas.1315883111⟩
To identify lipids with roles in tuberculosis disease, we systematically compared the lipid content of virulent Mycobacterium tuberculosis with the attenuated vaccine strain Mycobacterium bovis bacillus Calmette-Guerin. Comparative lipidomics analysi
Autor:
Emilie Layre, Jennifer H.C. Tsai, Jessica C. Seeliger, James C. Sacchettini, John W. Annand, M. Mahmood Hussain, Tan-Yun Cheng, Eric J. Rubin, Mary F. Farrow, Lu Bai, Zuri A. Sullivan, Jahangir Iqbal, D. Branch Moody, Amanda J. Martinot
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 1, p e1005351 (2016)
PLoS Pathogens, Vol 12, Iss 1, p e1005351 (2016)
Mycobacterium tuberculosis (Mtb) mutants lacking rv1411c, which encodes the lipoprotein LprG, and rv1410c, which encodes a putative efflux pump, are dramatically attenuated for growth in mice. Here we show that loss of LprG-Rv1410 in Mtb leads to int
Autor:
D. Branch Moody, Marie T Turner, Luis E. De León, Ravi C. Kalathur, John Shires, Tan Yun Cheng, John W. Annand, Michael B. Brenner, André Schiefner, Ian A. Wilson, Chetan Seshadri, John D. Altman, Anne Kasmar, Ildiko Van Rhijn, Annemieke de Jong
Publikováno v:
The Journal of Experimental Medicine
Glucose monomycolate–loaded CD1b tetramers identify a subset of CD4+ T cells in patients with Mycobacterium tuberculosis infection.
Microbial lipids activate T cells by binding directly to CD1 and T cell receptors (TCRs) or by indirect effects
Microbial lipids activate T cells by binding directly to CD1 and T cell receptors (TCRs) or by indirect effects
Publikováno v:
Journal of environmental health. 71(6)
After reports of increased severity of bacterial infections from community institutions, a broad spectrum of 70 surfaces was sampled for potential bacterial pathogens in the morning and afternoon of one day per week over three consecutive weeks in a
Publikováno v:
Journal of environmental health. 71(6)
Telephones can carry potential bacterial pathogens, posing a risk for transfer of pathogens to users' hands. This study examined 25 mouthpieces of public telephones at a large urban U.S. university located in an area of rising incidence of community-