Applying Meta-Analytic-Predictive Priors with the R Bayesian Evidence Synthesis Tools

Autor: Sebastian Weber, Yue Li, John W. Seaman III, Tomoyuki Kakizume, Heinz Schmidli

Publikováno v: Journal of Statistical Software, Vol 100, Pp 1-32 (2021)

Use of historical data in clinical trial design and analysis has shown various advantages such as reduction of number of subjects and increase of study power. The metaanalytic-predictive (MAP) approach accounts with a hierarchical model for between-t

Externí odkaz: https://doaj.org/article/69c05d11bda5431eb8eb6654b602e961

Continuous Method Validation: Beyond One-Time Studies to Characterize Analytical Methods

Autor: Paul Faya, Steven Novick, John W. Seaman, John J. Peterson, Tony Pourmohamad, Dwaine Banton, Yanbing Zheng

Publikováno v: Statistics in Biopharmaceutical Research. 15:225-233

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2705ae6bf2f3e091a3bb896b025e63e8
https://doi.org/10.1080/19466315.2022.2036637

An Overview of Bayesian Computation

Autor: David J. Kahle, John W. Seaman, James D. Stamey

Publikováno v: Case Studies in Bayesian Methods for Biopharmaceutical CMC ISBN: 9781003255093

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bb087835bb1910b23c1490f09814572
https://doi.org/10.1201/9781003255093-2

A Bayesian approach to correct for unmeasured or semi-unmeasured confounding in survival data using multiple validation data sets

Autor: Douglas E. Faries, Wencong Chen, James D. Stamey, John W. Seaman, Wei Shen, Xiang Zhang

Publikováno v: Epidemiology, Biostatistics, and Public Health; V. 14 N. 4 (2017)
Epidemiology, Biostatistics, and Public Health; Vol. 14 No. 4 (2017)
Epidemiology, Biostatistics and Public Health; Vol 14, No 4 (2017)

Purpose: The existence of unmeasured confounding can clearly undermine the validity of an observational study. Methods of conducting sensitivity analyses to evaluate the impact of unmeasured confounding are well established. However, application of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a40eed99b8f02f6ce991e5a6820a28
https://riviste.unimi.it/index.php/ebph/article/view/17474

Topical Ocular Anti-TNFα Agent Licaminlimab in the Treatment of Acute Anterior Uveitis: A Randomized Phase II Pilot Study

Autor: Theodore A, Pasquali, Melissa M, Toyos, David B, Abrams, David K, Scales, John W, Seaman, Georges, Weissgerber

Publikováno v: Translational Vision Science & Technology. 11:14

Licaminlimab is a new anti-TNFα antibody fragment for topical ocular application. This phase II study assessed the tolerability, treatment effect, and pharmacokinetics of licaminlimab in acute anterior uveitis (AAU).In this multicenter, randomized,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5117d17351bd08894d8cbfa3d3c9b978
https://doi.org/10.1167/tvst.11.6.14