Zobrazeno 1 - 10
of 53
pro vyhledávání: '"John W, Kuluz"'
Publikováno v:
Neurocritical Care. 23:129-135
There are many causes of acute myelopathy including multiple sclerosis, systemic disease (SD), and acute spinal cord compression (SCC). SCC should be among the first potential causes considered given the significant permanent loss of neurologic funct
Autor:
Randal R. Betz, Roosevelt De Los Santos, Allan D. Levi, John W. Kuluz, Tingting Huang, Mike Nares, David Hutchinson, Manuel Gonzalez-Brito, Miguel A. Ramirez, Kyle R. Padgett, Dansha He, Juan P. Solano, David M. Benglis, Ali Luqman, Dalton W. Dietrich, Amer F. Samdani
Publikováno v:
Scopus-Elsevier
To develop a new, clinically relevant large animal model of pediatric spinal cord injury (SCI) and compare the clinical and experimental features of pediatric SCI.Infant piglets (3-5 weeks old) underwent contusive SCI by controlled cortical impactor
Publikováno v:
Journal of Neurotrauma. 26:1535-1545
Hyperthermia is common following traumatic brain injury (TBI) and has been associated with poor neurologic outcome, and hypothermia has emerged as a potentially effective therapy for TBI, although its mechanism is still unclear. In this study we inve
Autor:
Tulay Koru-Sengul, Juan P. Solano, John W. Kuluz, John T. Landrum, Carol K. Petito, Kyle R. Padgett, David I. Sandberg, Darwin Babino, Manuel Gonzalez-Brito, Kenneth M. Crandall
Publikováno v:
Journal of Neuro-Oncology. 97:25-32
We hypothesize that infusion of chemotherapeutic agents directly into the fourth ventricle potentially may play a role in treating malignant posterior fossa brain tumors. Accordingly, we used a piglet model developed in our laboratory to test the saf
Publikováno v:
Future Neurology. 3:199-216
Pediatric stroke research presents many challenges. Relatively low incidence, need for age stratification, diverse etiologies, delays in diagnosis, lack of an established age-based stroke severity scale and outcome measures are only some of the issue
Publikováno v:
Hormone Research in Paediatrics. 70:29-35
Background/Aims: Children born small for gestational age (SGA) are at increased risk for short stature and type 2 diabetes mellitus as a result of growth hormone (GH) resistance and insulin resistance. The mechanisms of multiple hormone resistance re
Publikováno v:
Pediatric Critical Care Medicine. 6:550-556
Our objectives were, first, to compare mothers' and fathers' early reactions (stressors, concerns) to the preschool child's head injury, their perceptions of the child's injury severity, and their social support and mental health; second, to compare
Publikováno v:
Journal of Neurochemistry. 91:429-437
Transient brain hypoxia-ischemia (HI) in neonates leads to delayed neuronal death and long-term neurological deficits. However, the underlying mechanisms are incompletely understood. Calcium-calmodulin-dependent protein kinase II (CaMKII) is one of t
Publikováno v:
Critical Care Medicine. 30:1576-1580
Objective: To measure the effect of pre-ischemic administration of intraluminal epidermal growth factor on the changes in intestinal permeability induced by 30 mins of superior mesenteric artery occlusion, followed by 2 hrs of reperfusion. Design: Pr
Publikováno v:
Pediatric Critical Care Medicine. 2:88-92
OBJECTIVE: To test the hypothesis that cerebral and other regional organ blood flow would be maintained during partial liquid ventilation (PLV) in an animal model of acute lung injury during different ventilation strategies. DESIGN: A prospective, ra