Zobrazeno 1 - 10
of 120
pro vyhledávání: '"John W, Karanian"'
Autor:
Joshua Owen, Ayele H. Negussie, Scott R. Burks, Jose Delgado, Andrew S. Mikhail, Jocelyne Rivera, William F. Pritchard, John W. Karanian, Eleanor Stride, Joseph A. Frank, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Transarterial chemoembolization (TACE) is an image-guided minimally invasive treatment for liver cancer which involves delivery of chemotherapy and embolic material into tumor-supplying arteries to block blood flow to a liver tumor and to de
Externí odkaz:
https://doaj.org/article/c9a49119fd1745cfbd2e2feef1e8a23f
Autor:
Jose F. Delgado, Joshua W. Owen, William F. Pritchard, Nicole A. Varble, Tania L. Lopez-Silva, Andrew S. Mikhail, Antonio Arrichiello, Trisha Ray, Robert Morhard, Tabea Borde, Laetitia Saccenti, Sheng Xu, Jocelyne Rivera, Joel P. Schneider, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Intratumoral injections have the potential for enhanced cancer treatment efficacy while reducing costs and systemic exposure. However, intratumoral drug injections can result in substantial off-target leakage and are invisible under standard
Externí odkaz:
https://doaj.org/article/2731478a74a94c528685239e866607f1
Autor:
Jose F. Delgado, William F. Pritchard, Nicole Varble, Tania L. Lopez-Silva, Antonio Arrichiello, Andrew S. Mikhail, Robert Morhard, Trisha Ray, Michal M. Havakuk, Alex Nguyen, Tabea Borde, Joshua W. Owen, Joel P. Schneider, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Liver cancer ranks as the fifth leading cause of cancer-related death globally. Direct intratumoral injections of anti-cancer therapeutics may improve therapeutic efficacy and mitigate adverse effects compared to intravenous injections. Some
Externí odkaz:
https://doaj.org/article/68305af4433440b69466194e5cca2e34
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hepatocellular carcinoma (HCC) is an aggressive liver cancer with limited effective treatment options. In this study, we selected TLR agonists imiquimod (IMQ), gardiquimod (GARD), GS-9620 and DSR 6434, and a small molecule checkpoint inhibit
Externí odkaz:
https://doaj.org/article/a5f7912257d54f5cb2ffe67f7c41928a
Autor:
Michal Mauda-Havakuk, Natalie M. Hawken, Joshua W. Owen, Andrew S. Mikhail, Ankit Saxena, Baktiar Karim, Paul G. Wakim, William F. Pritchard, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The immune response to radiofrequency ablation (RFA) and cryoablation (CRA) was characterized and compared in a colon cancer mouse model. All studies were conducted under a research protocol approved by the National Institutes of Health, Cli
Externí odkaz:
https://doaj.org/article/1b3f5f53145044b186cc82ab49b63fa9
Autor:
Nicole A Varble, Ivane Bakhutashvili, Sheridan L Reed, Jose Delgado, Zoi Tokoutsi, Bruno Frackowiak, Marco Baragona, John W Karanian, Bradford J Wood, William F Pritchard
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289674 (2023)
PurposeHeat-induced destruction of cancer cells via microwave ablation (MWA) is emerging as a viable treatment of primary and metastatic liver cancer. Prediction of the impacted zone where cell death occurs, especially in the presence of vasculature,
Externí odkaz:
https://doaj.org/article/392a50797c064d578e9f32c055a33ce4
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/21cccb8cdbf44c99b3ea9c43414d7873
Autor:
Juan A Esparza-Trujillo, William F Pritchard, Michal Mauda-Havakuk, Matthew F Starost, Paul Wakim, Johnathan Zeng, Andrew S Mikhail, Ivane Bakhutashvili, Bradford J Wood, John W Karanian
Publikováno v:
Comparative Medicine. 73:127-133
We characterized cryoablation as a mode of clinical intervention in adult woodchucks with hepatocellular carcinoma (HCC). Woodchucks (n = 4) were infected with woodchuck hepatitis virus at birth and developed LI-RADS-5 hypervascular HCC. At 21 mo of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6021c4538a211041b4628deb1586a665
https://doi.org/10.30802/aalas-cm-22-000092
https://doi.org/10.30802/aalas-cm-22-000092
Autor:
Andrew S Mikhail, Michal Mauda-Havakuk, Ari Partanen, John W Karanian, William F Pritchard, Bradford J Wood
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230794 (2020)
PurposeTo evaluate the spatial registration and correlation of liver and tumor histopathology sections with corresponding in vivo CT and MRI using 3D, liver-specific cutting molds in a woodchuck (Marmota monax) hepatic tumor model.MethodsFive woodchu
Externí odkaz:
https://doaj.org/article/db5a7ae44ecf4ff4a085560b064941ed
Autor:
William F. Pritchard, John W. Karanian, Chris Jung, Ivane Bakhutashvili, Sheridan L. Reed, Matthew F. Starost, Brian R. Froelke, Teresa R. Barnes, Duncan Stevenson, Artemio Mendoza, David J. Eckstein, Bradford J. Wood, Brian K. Walsh, Andrew J. Mannes
Publikováno v:
Sci Transl Med
The COVID-19 pandemic demonstrated the need for inexpensive, easy-to-use, rapidly mass-produced resuscitation devices that could be quickly distributed in areas of critical need. In-line miniature ventilators based on principles of fluidics ventilate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87620806040b63ccc21dee79713ab6f
https://doi.org/10.1126/scitranslmed.abm8351
https://doi.org/10.1126/scitranslmed.abm8351