Zobrazeno 1 - 10
of 22
pro vyhledávání: '"John W, Cherwonogrodzky"'
Publikováno v:
Toxins, Vol 6, Iss 1, Pp 380-393 (2014)
Therapeutic antibodies can confer an instant protection against biothreat agents when administered. In this study, intact IgG and F(ab’)2 from goat anti-ricin hyperimmune sera were compared for the protection against lethal ricin mediated intoxicat
Externí odkaz:
https://doaj.org/article/24987dd26ff947f38785e3c7ab0dd34b
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45595 (2012)
Ricin is regarded as a high terrorist risk for the public due to its high toxicity and ease of production. Currently, there is no therapeutic or vaccine available against ricin. D9, a murine monoclonal antibody developed previously in our laboratory,
Externí odkaz:
https://doaj.org/article/2d336b1f6cfb4fd68ff6ac8e8cbe1cc2
Publikováno v:
Toxins
Toxins, Vol 6, Iss 1, Pp 380-393 (2014)
Volume 6
Issue 1
Pages 380-393
Toxins, Vol 6, Iss 1, Pp 380-393 (2014)
Volume 6
Issue 1
Pages 380-393
Therapeutic antibodies can confer an instant protection against biothreat agents when administered. In this study, intact IgG and F(ab’)2 from goat anti-ricin hyperimmune sera were compared for the protection against lethal ricin mediated intoxicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b115bd81a4b3bc30cdaa9b3530831f1
https://doi.org/10.3390/toxins6010380
https://doi.org/10.3390/toxins6010380
Autor:
Charles C. Hu, Wei-Gang Hu, Laurel M. Negrych, Dustin Lillico, Damon Chau, John W. Cherwonogrodzky, Junfei Yin, Justin Yu
Publikováno v:
BioMed Research International, Vol 2013 (2013)
BioMed Research International
BioMed Research International
Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcd13dae5620074f1cf1422b20bc6d9
https://doi.org/10.1155/2013/471346
https://doi.org/10.1155/2013/471346
Autor:
Fei Yu, Chris Druar, Donald I. H. Stewart, John W. Cherwonogrodzky, Natkunam Ketheesan, Robert Norton, Narisara Chantratita, Richard T. Okinaka, William D. Picking, Glenn Soltes, Chad W. Stratilo, Erik J. Wiersma, Andrew J. Olive, Vadim Tsvetnitsky, Sally Xueying Ni, Paul J. Jackson, Steve Beg, Sharon J. Peacock, Jodie L. Barnes, Direk Limmathurotsakul, Michelle L. Russell, Wendy L. Picking
Publikováno v:
FEMS Immunology & Medical Microbiology. 52:78-87
Burkholderia pseudomallei is a biothreat agent and an important natural pathogen, causing melioidosis in humans and animals. A type III secretion system (TTSS-3) has been shown to be critical for virulence. Because TTSS components from other pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244df9e308dc23c8fa843a21bcaec9bc
https://doi.org/10.1111/j.1574-695x.2007.00345.x
https://doi.org/10.1111/j.1574-695x.2007.00345.x
Autor:
Nicole D. Barabé, Bradley J. Berger, Scott Jager, Robert T. Poirier, William E. Lee, John W. Cherwonogrodzky, Michelle L. Grigat
A subunit vaccine candidate was produced from Brucella suis 145 (biovar 4; expressing both the A antigen of Brucella abortus and the M antigen of Brucella melitensis ). The preparation consisted mostly of polysaccharide (PS; >90% [wt/wt]; both cell-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cea98c8ae2a779a426c023af6c915d
https://europepmc.org/articles/PMC4248776/
https://europepmc.org/articles/PMC4248776/
Autor:
John W. Cherwonogrodzky
Publikováno v:
Journal of Bioterrorism & Biodefense.
The Brucella species are easily grown, highly infectious to humans by the aerosol route and resistant to harsh environments. These traits have contributed to these being part of the biological weapons programs in the United States (1943-1969), former
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a78580010f4fa9aeb63d10acc9ef4b
https://doi.org/10.4172/2157-2526.s3-012
https://doi.org/10.4172/2157-2526.s3-012
Publikováno v:
Journal of Clinical Microbiology. 35:295-297
A serological and bacteriological study was performed with sera taken from 2,228 swine from six states in Venezuela. None of the animals were vaccinated against brucellosis, and the prevalence of the disease varied from 5 to 89% on farms located in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6756ad3460a4b1549b9f90f0a8f98b0f
https://doi.org/10.1128/jcm.35.1.295-297.1997
https://doi.org/10.1128/jcm.35.1.295-297.1997