Zobrazeno 1 - 10
of 165
pro vyhledávání: '"John W, Calvert"'
Autor:
Nikolay Bogush, Lin Tan, Emmen Naqvi, John W. Calvert, Robert M. Graham, W. Robert Taylor, Nawazish Naqvi, Ahsan Husain
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Renewal of the myocardium by preexisting cardiomyocytes is a powerful strategy for restoring the architecture and function of hearts injured by myocardial infarction. To advance this strategy, we show that combining two clinically approved d
Externí odkaz:
https://doaj.org/article/25701309779d495686c246bf34bbcfeb
Autor:
Junya Suzuki, Yuuki Shimizu, Takumi Hayashi, Yiyang Che, Zhongyue Pu, Kazuhito Tsuzuki, Shingo Narita, Rei Shibata, Isao Ishii, John W. Calvert, Toyoaki Murohara
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Accumulating evidence suggests that hydrogen sulfide ( H2S ), an endogenously produced gaseous molecule, plays a critical role in the regulation of cardiovascular homeostasis. However, little is known about its role in lymphangiogenesis. T
Externí odkaz:
https://doaj.org/article/51e04ef600904c6890179a0aae21a0bc
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract DJ-1 is a ubiquitously expressed protein that protects cells from stress through its conversion into an active protease. Recent work found that the active form of DJ-1 was induced in the ischemic heart as an endogenous mechanism to attenuate
Externí odkaz:
https://doaj.org/article/edca3d41b4134b81ac974e626b3347aa
Autor:
Nikolay Bogush, Lin Tan, Hussain Naib, Ebrahim Faizullabhoy, John W. Calvert, Siiri E. Iismaa, Ankan Gupta, Ramani Ramchandran, David I. K. Martin, Robert M. Graham, Ahsan Husain, Nawazish Naqvi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Cardiomyocytes of newborn mice proliferate after injury or exposure to growth factors. However, these responses are diminished after postnatal day-6 (P6), representing a barrier to building new cardiac muscle in adults. We have previously sh
Externí odkaz:
https://doaj.org/article/fd5f777a271c4c42af5f2172602fd2f5
Autor:
Kazuhito Tsuzuki, Yuuki Shimizu, Junya Suzuki, Zhongyue Pu, Shukuro Yamaguchi, Yusuke Fujikawa, Katsuhiro Kato, Koji Ohashi, Mikito Takefuji, Yasuko K. Bando, Noriyuki Ouchi, John W. Calvert, Rei Shibata, Toyoaki Murohara
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background Circadian rhythm disorders, often seen in modern lifestyles, are a major social health concern. The aim of this study was to examine whether circadian rhythm disorders would influence angiogenesis and blood perfusion recovery in a mouse mo
Externí odkaz:
https://doaj.org/article/d58d5a2c769d490ea595b61542a62eaf
Autor:
Yuuki Shimizu, Chad K. Nicholson, Rohini Polavarapu, Yvanna Pantner, Ahsan Husain, Nawazish Naqvi, Lih‐Shen Chin, Lian Li, John W. Calvert
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)
Background DJ‐1 is a ubiquitously expressed protein typically associated with the development of early onset Parkinson disease. Recent data suggest that it also plays a role in the cellular response to stress. Here, we sought to determine the role
Externí odkaz:
https://doaj.org/article/454ddee5519d4b83b7cd5d6673f04554
Autor:
Zhen, Li, Huijing, Xia, Thomas E, Sharp, Kyle B, LaPenna, John W, Elrod, Kevin M, Casin, Ken, Liu, John W, Calvert, Vinh Q, Chau, Fadi N, Salloum, Shi, Xu, Ming, Xian, Noriyuki, Nagahara, Traci T, Goodchild, David J, Lefer
Publikováno v:
Circulation research. 131(3)
Hydrogen sulfide (HHuman myocardial samples obtained from patients with heart failure undergoing cardiac surgeries were probed for 3-MST protein expression. 3-MST knockout mice and C57BL/6J wild-type mice were subjected to transverse aortic constrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2c9d8f4c0c17bc12d88be38f77e19b4
https://pubmed.ncbi.nlm.nih.gov/36173826
https://pubmed.ncbi.nlm.nih.gov/36173826
Autor:
Kevin M. Casin, John W. Calvert
Publikováno v:
Cells, Vol 10, Iss 9, p 2388 (2021)
Myocardial ischemia–reperfusion (I/R) injury significantly alters heart function following infarct and increases the risk of heart failure. Many studies have sought to preserve irreplaceable myocardium, termed cardioprotection, but few, if any, tre
Externí odkaz:
https://doaj.org/article/a0a28afe64d845eebd338eb16ce62073
Autor:
Zhen Li, Huijing Xia, Thomas E. Sharp, Kyle B. LaPenna, John W. Elrod, Kevin M. Casin, Ken Liu, John W. Calvert, Vinh Q. Chau, Fadi N. Salloum, Shi Xu, Ming Xian, Noriyuki Nagahara, Traci T. Goodchild, David J. Lefer
Publikováno v:
Circulation Research. 131:222-235
Background: Hydrogen sulfide (H 2 S) exerts mitochondria-specific actions that include the preservation of oxidative phosphorylation, biogenesis, and ATP synthesis, while inhibiting cell death. 3-MST (3-mercaptopyruvate sulfurtransferase) is a mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2be06cd506203f0642240dbc5df8362
https://doi.org/10.1161/circresaha.121.319817
https://doi.org/10.1161/circresaha.121.319817
Autor:
Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon
Publikováno v:
Circulation.
BACKGROUND: Shortly after birth, cardiomyocytes exit the cell cycle and cease proliferation. At present, the regulatory mechanisms for this loss of proliferative capacity are poorly understood. CBX7 (chromobox 7), a polycomb group (PcG) protein, regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7506c2fde2f898b5333484ccf9180400
https://doi.org/10.1161/circulationaha.122.061131
https://doi.org/10.1161/circulationaha.122.061131