Zobrazeno 1 - 10
of 345
pro vyhledávání: '"John W, Barrett"'
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Autor:
Corby Fink, Julia J. Gevaert, John W. Barrett, Jimmy D. Dikeakos, Paula J. Foster, Gregory A. Dekaban
Publikováno v:
European Radiology Experimental, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Background Despite widespread study of dendritic cell (DC)-based cancer immunotherapies, the in vivo postinjection fate of DC remains largely unknown. Due in part to a lack of quantifiable imaging modalities, this is troubling as the amount
Externí odkaz:
https://doaj.org/article/1efb13964c7743ad84a46c760b57440c
Autor:
Steven F. Gameiro, Mikhail Y. Salnikov, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
Viruses, Vol 15, Iss 12, p 2411 (2023)
Human papillomavirus (HPV) is the major causative agent for cervical and many head and neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that may become established via positive selection. Within an HPV type, viral iso
Externí odkaz:
https://doaj.org/article/8cdc15fdb1154c088967c5e89ad98748
Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma
Autor:
Tomonori Kaneko, Peter Y. F. Zeng, Xuguang Liu, Rober Abdo, John W. Barrett, Qi Zhang, Anthony C. Nichols, Shawn Shun-Cheng Li
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-15 (2022)
Kaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-me
Externí odkaz:
https://doaj.org/article/a44ce57f6a334a38873bee17ae0c6444
Autor:
Nicole Pinto, Kara M. Ruicci, Mohammed Imran Khan, Mushfiq Hassan Shaikh, Yu Fan Peter Zeng, John Yoo, Kevin Fung, S. Danielle MacNeil, Adrian Mendez, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Journal of Otolaryngology - Head and Neck Surgery, Vol 51, Iss 1, Pp 1-10 (2022)
Abstract Anaplastic thyroid cancer (ATC) is a rare, aggressive form of undifferentiated thyroid cancer, which exhibits rapid progression and is almost universally fatal. At least a subset of ATC is thought to arise from pre-existing well-differentiat
Externí odkaz:
https://doaj.org/article/1d4bd87a76b449ceb48baa3fbf13dd24
Autor:
Peter Y.F. Zeng, Matthew J. Cecchini, John W. Barrett, Matthew Shammas-Toma, Loris De Cecco, Mara S. Serafini, Stefano Cavalieri, Lisa Licitra, Frank Hoebers, Ruud H. Brakenhoff, C. René Leemans, Kathrin Scheckenbach, Tito Poli, Xiaowei Wang, Xinyi Liu, Francisco Laxague, Eitan Prisman, Catherine Poh, Pinaki Bose, Joseph C. Dort, Mushfiq H. Shaikh, Sarah E.B. Ryan, Alice Dawson, Mohammed I. Khan, Christopher J. Howlett, William Stecho, Paul Plantinga, Sabrina Daniela da Silva, Michael Hier, Halema Khan, Danielle MacNeil, Adrian Mendez, John Yoo, Kevin Fung, Pencilla Lang, Eric Winquist, David A. Palma, Hedyeh Ziai, Antonio L. Amelio, Shawn S-C. Li, Paul C. Boutros, Joe S. Mymryk, Anthony C. Nichols
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104373- (2022)
Summary: Background: There is significant interest in treatment de-escalation for human papillomavirus-associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients given the generally favourable prognosis. However, 15–30% of patients re
Externí odkaz:
https://doaj.org/article/1fa6271669f0432eb67d2b929bab5f9f
Autor:
Mikhail Salnikov, Steven F. Gameiro, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT Human papillomaviruses (HPVs) are highly infectious and cause the most common sexually transmitted viral infections. They induce hyperproliferation of squamous epithelial tissue, often forming warts. Virally encoded proteins reprogram gene e
Externí odkaz:
https://doaj.org/article/2657d1b773dc485f89420a45ebcca125
Autor:
Steven F. Gameiro, Farhad Ghasemi, Peter Y. F. Zeng, Neil Mundi, Christopher J. Howlett, Paul Plantinga, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
Infectious Agents and Cancer, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1 mutations are cor
Externí odkaz:
https://doaj.org/article/74f93a6ff6cd4c05bdc90a39355af0e2
Autor:
Eric J. Di Gravio, Pencilla Lang, Hugh Andrew Jinwook Kim, Tricia Chinnery, Neil Mundi, S. Danielle MacNeil, Adrian Mendez, John Yoo, Kevin Fung, Joe S. Mymryk, John W. Barrett, Nancy Read, Varagur Venkatesan, Sara Kuruvilla, Lucas C. Mendez, Eric Winquist, Sylvia Mitchell, Sarah A. Mattonen, Anthony C. Nichols, David A. Palma
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Transoral surgery (TOS), particularly transoral robotic surgery (TORS) has become the preferred modality in the United States for the treatment of early stage oropharyngeal cancer, largely due to assumptions of fewer toxicities an
Externí odkaz:
https://doaj.org/article/3b222f9a6b7849cfaa3f46309df045b6
Autor:
Kara M. Ruicci, Jalna Meens, Paul Plantinga, William Stecho, Nicole Pinto, John Yoo, Kevin Fung, Danielle MacNeil, Joe S. Mymryk, John W. Barrett, Christopher J. Howlett, Paul C. Boutros, Laurie Ailles, Anthony C. Nichols
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-18 (2020)
Abstract Background Aberrant activation of the phosphatidylinositol 3-kinase (PI3K) pathway is common in many malignancies, including head and neck squamous cell carcinoma (HNSCC). Despite pre-clinical and clinical studies, outcomes from targeting th
Externí odkaz:
https://doaj.org/article/3551d8a27ebe46f4ba35d980ed3dd3e5