Zobrazeno 1 - 10
of 10
pro vyhledávání: '"John Vasilakos"'
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7967 (2009)
C. albicans triggers recurrent infections of the alimentary tract mucosa that result from biofilm growth. Although the ability of C. albicans to form a biofilm on abiotic surfaces has been well documented in recent years, no information exists on bio
Externí odkaz:
https://doaj.org/article/b1aead45b97c4405960a41afa94da64b
Publikováno v:
Frontiers in Tropical Diseases. 3
Effective and simple delivery of DNA vaccines remains a key to successful clinical applications. Previously, we developed a novel class of DNA vaccines, sometimes called iDNA, which encodes the whole live-attenuated vaccine viruses. Compared to a sta
Autor:
Yoichiro Iwakura, Jun Yan, Keqing Qian, Chuanlin Ding, Goetz H. Kloecker, Bing Li, John Vasilakos, Shinobu Saijo, Chunjian Qi, John R. Yannelli, Yihua Cai, Lacey Gunn
Publikováno v:
Blood. 117(25)
β-glucans have been reported to function as a potent adjuvant to stimulate innate and adaptive immune responses. However, β-glucans from different sources are differential in their structure, conformation, and thus biologic activity. Different prep
Autor:
John Vasilakos, Hervé Lebrec
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781588294678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599d062ab7af4ee095f750198ec716b1
https://doi.org/10.1007/978-1-59745-350-9_3
https://doi.org/10.1007/978-1-59745-350-9_3
Autor:
Saranya Elavazhagan, Prexy Shah, Kavin Fatehchand, Hemal Patel, Carolyn Cheney, Natarajan Muthusamy, John Vasilakos, Maura-Ann Matthews, Gregory Dietsch, Robert Hershberg, John Byrd, Susheela Tridandapani, Jonathan Butchar
Publikováno v:
The Journal of Immunology. 192:203.40-203.40
Monoclonal antibody therapy has been used to treat cancer since 1997, but there is a continued need to improve its effectiveness. We have previously shown that the TLR7/8 dual agonist R-848 could modulate monocyte FcγR expression and function, and t
Autor:
William Grossman, Anissa Chan, Keith Gorden, Adria Bykowski-Jonas, Richard Walsh, Katie Ertelt, John Vasilakos, Mary Antonysamy, Nadine Ottoson, Nandita Bose
Publikováno v:
The Journal of Immunology. 188:55.8-55.8
β-glucans are considered as fungal pathogen-associated molecular patterns (PAMPs) that are recognized by cells of the human innate immune system. Few studies have focused on recognition and immunostimulatory functions of soluble β-glucan (sβG) on
Autor:
John Vasilakos, Nandita Bose, Anissa Chan, Michael Danielson, Christine Dudney, Natalie Elmasry, Keith Gorden, Faimola Guerrero, Andy Magee, Carolyn Maristany, Richard Walsh, Paul Will, Lindsay Wurst
Publikováno v:
The Journal of Immunology. 184:89.53-89.53
Beta-1,3/1,6 glucans (BGs) are a diverse class of PAMPs. Structurally, BGs can vary on the basis of chain length, types of linkages, branching, and tertiary structure. BGs have been reported to activate various types of innate immune cells; most stud
Autor:
Mark Allen Tomai, Linda Pederson, John Vasilakos, Kevin Gorski, Laxma Reddy, Gerry O’Sullivan, Rodney Frank, Terri Prestegard, William Kieper
Publikováno v:
The Journal of Immunology. 178:LB38-LB38
TLR agonists have been used in treating diseases including infections, cancer and as vaccine adjuvants. Aldara™ (imiquimod 5% cream) is the first TLR7 agonist approved in the US, and is indicated for the treatment of genital warts caused by human p
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