Zobrazeno 1 - 10
of 72
pro vyhledávání: '"John V. Schloss"'
Autor:
John V. Schloss
The rational design of compounds with desirable biological properties has long been the dream of many pharmaceutical and agrochemical concerns. While normally barriers to the action of a potential drug or agrochemical, differences in accessibility or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d62bb6eb52117922b6374bcda02890a
https://doi.org/10.1201/9781003068280-9
https://doi.org/10.1201/9781003068280-9
Autor:
Jennifer Schnepp, Gregory J. Peel, Christine M. Kish, David Rhodes, Karl V. Wood, Alexander Vainstein, David Weiss, Yasuhisa Kaminaga, Orly Lavie, D. Marshall Porterfield, Arthur J.L. Cooper, Gili Ben-Nissan, Irina Orlova, Eran Pichersky, John V. Schloss, Natalia Dudareva
Publikováno v:
Journal of Biological Chemistry. 281:23357-23366
We have isolated and characterized Petunia hybrida cv. Mitchell phenylacetaldehyde synthase (PAAS), which catalyzes the formation of phenylacetaldehyde, a constituent of floral scent. PAAS is a cytosolic homotetrameric enzyme that belongs to group II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147a264c465359d6d83fbbce9699f352
https://doi.org/10.1074/jbc.m602708200
https://doi.org/10.1074/jbc.m602708200
Autor:
John V. Schloss
Publikováno v:
Planta. 216:38-43
Over the past 30 years, acute oxygen toxicity in plants, mammals and enteric bacteria has been defined in terms of specific interactions of oxygen with a limited number of molecular targets. At least in the case of plants and mammals, response at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd9253b7c8a65c81959dd9fc28ddfd9
https://doi.org/10.1007/s00425-002-0905-3
https://doi.org/10.1007/s00425-002-0905-3
Publikováno v:
Journal of Biomedical Science. 8:359-364
The recombinant forms of the two human isozymes of glutamate decarboxylase, GAD65 and GAD67, are potently and reversibly inhibited by molecular oxygen (Ki = 0.46 and 0.29 mM, respectively). Inhibition of the vesicle-associated glutamate decarboxylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e906d7ad6bade4c59711e6d82af07eb5
https://doi.org/10.1007/bf02258378
https://doi.org/10.1007/bf02258378
Publikováno v:
Journal of Biomedical Science. 8:104-113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5902895821d5d7615d55087b383afdce
https://doi.org/10.1159/000054020
https://doi.org/10.1159/000054020
Autor:
Kathleen Davis, Todd Foos, Erik Floor, John V. Schloss, Chao-Yuh Yang, John B. Tyburski, Jang-Yen Wu, Hong Jin, Che-Chang Hsu, Weiqing Chen
Publikováno v:
Journal of Biological Chemistry. 275:20822-20828
Recently we have reported that the membrane-associated form of the gamma-aminobutyric acid-synthesizing enzyme, l-glutamate decarboxylase (MGAD), is regulated by the vesicular proton gradient (Hsu, C. C., Thomas, C., Chen, W., Davis, K. M., Foos, T.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0db4863af15aa66ac76fee9e20ed560
https://doi.org/10.1074/jbc.m001403200
https://doi.org/10.1074/jbc.m001403200
Publikováno v:
Journal of Neuroscience Research. 62:600-607
Derivatives of C(60) have been shown to be effective free radical scavengers. Hence, many of the biological functions of fullerene are believed to be due to their antioxidant properties. Here we present evidence to show that fullerenols, that are cag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b03bc634f96482bbe9b2179e0c69cc
https://doi.org/10.1002/1097-4547(20001115)62:4<600::aid-jnr15>3.0.co
https://doi.org/10.1002/1097-4547(20001115)62:4<600::aid-jnr15>3.0.co
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1385:401-419
Two groups of enzymes are classified as acetolactate synthase (EC 4. 1.3.18). This review deals chiefly with the FAD-dependent, biosynthetic enzymes which readily catalyze the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d6b75f673c562ef5d3a36eea488f6d
https://doi.org/10.1016/s0167-4838(98)00083-1
https://doi.org/10.1016/s0167-4838(98)00083-1
Publikováno v:
Biochemical Pharmacology. 55:749-756
S -Methyl N , N -diethylthiolcarbamate sulfoxide (DETC-MeSO) and sulfone (DETC-MeSO 2 ) both inhibit rat liver low K m aldehyde dehydrogenase (ALDH 2 ) in vitro and in vivo (Nagendra et al ., Biochem Pharmacol 47: 1465–1467, 1994). DETC-MeSO has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af98bd6fc982fae6b2c9593024f43aa3
https://doi.org/10.1016/s0006-2952(97)00513-3
https://doi.org/10.1016/s0006-2952(97)00513-3
Autor:
Xiangyue Newby, S. Ningaraj Nagendra, Kathleen Davis, Jang-Yen Wu, Morris D. Faiman, John V. Schloss
Publikováno v:
Journal of Biological Chemistry. 272:24247-24251
S-Methyl-N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO), a metabolite of the drug disulfiram, is a selective carbamoylating agent for sulfhydryl groups. Treatment of glutamate receptors isolated from mouse brain with DETC-MeSO blocks glutamate bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0b4aa2ee1a4f6431095bf79d1478cf
https://doi.org/10.1074/jbc.272.39.24247
https://doi.org/10.1074/jbc.272.39.24247