Zobrazeno 1 - 10
of 83
pro vyhledávání: '"John V. Conaglen"'
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Background Sexually dimorphic growth has been attributed to the growth hormone (GH)/insulin-like growth factor 1 (IGF1) axis, particularly GH-induced activation of the intracellular signal transducer and activator of transcription 5B (STAT5B
Externí odkaz:
https://doaj.org/article/e380a07bf28141cf8026b541c33b29d8
Publikováno v:
International Journal of Endocrinology, Vol 2016 (2016)
Despite 70 years of experience treating thyrotoxic patients with radioiodine not all patients are successfully treated by a single dose. Multiple factors predicting radioiodine efficacy have been reported. The aim of this study was to assess whether
Externí odkaz:
https://doaj.org/article/cdc3acb7ba8d445fbf9162e84e0ce51e
Autor:
Marianne S. Elston, Goswin Y. Meyer-Rochow, Michael Dray, Michael Swarbrick, John V. Conaglen
Publikováno v:
Case Reports in Endocrinology, Vol 2015 (2015)
Individuals presenting with primary hyperparathyroidism (PHPT) at a young age commonly have an underlying germline gene mutation in one of the following genes: MEN1, CASR, or CDC73. A small number of families with primary hyperparathyroidism have bee
Externí odkaz:
https://doaj.org/article/95a68c7df7bb4d198df3e1cedf479082
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Purpose. Excess growth hormone secretion in adults results in acromegaly, a condition in which multiple physical changes occur including bony and soft tissue overgrowth. Over time these changes can markedly alter a person’s appearance. The aim of t
Externí odkaz:
https://doaj.org/article/e8455d4d7d664feca4292965457e83a6
Autor:
Sumaya Alkanderi, Stephen Du Toit, John A. Sayer, John V. Conaglen, Jade Tamatea, Marianne S. Elston
Publikováno v:
SN Comprehensive Clinical Medicine. 2:995-1002
Vitamin D–mediated hypercalcemia may be due to benign or malignant conditions. Recently, loss-of-function mutations in the gene CYP24A1, which encodes 25-hydroxyvitamin D3-24-hydroxylase, have been described which result in reduced degradation of t
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-13 (2019)
Skeletal Muscle
Skeletal Muscle
Background Sexually dimorphic growth has been attributed to the growth hormone (GH)/insulin-like growth factor 1 (IGF1) axis, particularly GH-induced activation of the intracellular signal transducer and activator of transcription 5B (STAT5B), becaus
Publikováno v:
Journal of the Endocrine Society
Background Māori, the indigenous people of Aotearoa/New Zealand, have an increased incidence of Graves disease and often require more than one radioiodine (RAI) dose, raising the question as to whether surgery may be preferable in this population. H
Publikováno v:
Journal of the Endocrine Society
Background Reported international incidence rates of thyrotoxicosis vary markedly, ranging from 6 to 93 cases per 100 000 per annum. Along with population demographics, exposures, and study design factors, ethnicity is increasingly being recognized a
Autor:
Marianne S. Elston, John V. Conaglen, Kenneth G. Matthews, Sarina Lim, Christopher D. McMahon, Gerard Devlin
Publikováno v:
Heart, Lung and Circulation. 27:693-701
Background Myostatin inhibits the development of skeletal muscle and regulates the proliferation of skeletal muscle fibroblasts. However, the role of myostatin in regulating cardiac muscle or myofibroblasts, specifically in acute myocardial infarctio
Publikováno v:
Clinical Endocrinology. 88:977-984
Background Thyrotoxicosis, most often caused by Graves' disease (GD), when treated inadequately may result in premature mortality. There is little consensus as to which of the 3 treatment options available - antithyroid drugs (ATD), radioactive iodin