Výsledky vyhledávání - "John V Deighan"

Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme

Autor: John V Deighan, S.K. Sundaram, John Marshall, Trinh Duong, Abdulla Alhasso, Ruth E Langley, M. Laniado, Roger Kockelbergh, Christopher D Scrase, Jane Worlding, Alvan Pope, Stuart D. Rosen, Matthew Nankivell, Edgar Paez, Howard Kynaston, S.T Williams, Iqtedar Ahmed Muazzam, Silvia Forcat, Gerald N. Collins, Angus Robinson, Sanjay Dixit, Noel W. Clarke, Caroline Manetta, Duncan C. Gilbert, Archie Macnair, Melanie Weiss, Mahesh K. B. Parmar, S. McKay, Sanjeev Madaan, Jonathan McFarlane, Stephen Mangar

Publikováno v: Lancet

BACKGROUND: Androgen suppression is a central component of prostate cancer management but causes substantial long-term toxicity. Transdermal administration of oestradiol (tE2) circumvents first-pass hepatic metabolism and, therefore, should avoid the

Vyhledávací nástroje:

Upřesnit hledání