Zobrazeno 1 - 10
of 206
pro vyhledávání: '"John Turnbull"'
Autor:
Miracle Ozzoude, Brenda Varriano, Derek Beaton, Joel Ramirez, Sabrina Adamo, Melissa F. Holmes, Christopher J. M. Scott, Fuqiang Gao, Kelly M. Sunderland, Paula McLaughlin, Maged Goubran, Donna Kwan, Angela Roberts, Robert Bartha, Sean Symons, Brian Tan, Richard H. Swartz, Agessandro Abrahao, Gustavo Saposnik, Mario Masellis, Anthony E. Lang, Connie Marras, Lorne Zinman, Christen Shoesmith, Michael Borrie, Corinne E. Fischer, Andrew Frank, Morris Freedman, Manuel Montero-Odasso, Sanjeev Kumar, Stephen Pasternak, Stephen C. Strother, Bruce G. Pollock, Tarek K. Rajji, Dallas Seitz, David F. Tang-Wai, John Turnbull, Dar Dowlatshahi, Ayman Hassan, Leanne Casaubon, Jennifer Mandzia, Demetrios Sahlas, David P. Breen, David Grimes, Mandar Jog, Thomas D. L. Steeves, Stephen R. Arnott, Sandra E. Black, Elizabeth Finger, Jennifer Rabin, ONDRI Investigators, Maria Carmela Tartaglia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2023)
Abstract Background Neuropsychiatric symptoms (NPS) are a core feature of most neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain atrophy have been implicated in NPS. We aimed to investigate the relative contribut
Externí odkaz:
https://doaj.org/article/3907d8c8f84f479f86cb887962bed6d4
Autor:
Allison A. Dilliott, Abdalla Abdelhady, Kelly M. Sunderland, Sali M. K. Farhan, Agessandro Abrahao, Malcolm A. Binns, Sandra E. Black, Michael Borrie, Leanne K. Casaubon, Dar Dowlatshahi, Elizabeth Finger, Corinne E. Fischer, Andrew Frank, Morris Freedman, David Grimes, Ayman Hassan, Mandar Jog, Sanjeev Kumar, Donna Kwan, Anthony E. Lang, Jennifer Mandzia, Mario Masellis, Adam D. McIntyre, Stephen H. Pasternak, Bruce G. Pollock, Tarek K. Rajji, Ekaterina Rogaeva, Demetrios J. Sahlas, Gustavo Saposnik, Christine Sato, Dallas Seitz, Christen Shoesmith, Thomas D. L. Steeves, Richard H. Swartz, Brian Tan, David F. Tang-Wai, Maria C. Tartaglia, John Turnbull, Lorne Zinman, ONDRI Investigators, Robert A. Hegele
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Genetic factors contribute to neurodegenerative diseases, with high heritability estimates across diagnoses; however, a large portion of the genetic influence remains poorly understood. Many previous studies have attempted to fill the gaps b
Externí odkaz:
https://doaj.org/article/c14898e55b0f4ab5b45663002d305766
Autor:
Allison A. Dilliott, Kristina K. Zhang, Jian Wang, Agessandro Abrahao, Malcolm A. Binns, Sandra E. Black, Michael Borrie, Dar Dowlatshahi, Elizabeth Finger, Corinne E. Fischer, Andrew Frank, Morris Freedman, David Grimes, Ayman Hassan, Mandar Jog, Sanjeev Kumar, Anthony E. Lang, Jennifer Mandzia, Mario Masellis, Stephen H. Pasternak, Bruce G. Pollock, Tarek K. Rajji, Ekaterina Rogaeva, Demetrios J. Sahlas, Gustavo Saposnik, Christine Sato, Dallas Seitz, Christen Shoesmith, Thomas D. L. Steeves, Richard H. Swartz, Brian Tan, David F. Tang‐Wai, Maria C. Tartaglia, John Turnbull, Lorne Zinman, ONDRI Investigators, Robert A. Hegele
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Background Although genetic factors are known to contribute to neurodegenerative disease susceptibility, there remains a large amount of heritability unaccounted for across the diagnoses. Copy number variants (CNVs) contribute to these pheno
Externí odkaz:
https://doaj.org/article/649dad53d67b47c99ebb458bbdb9833e
Autor:
O Selma Klanten, Michelle R Gaither, Samuel Greaves, Kade Mills, Kristine O'Keeffe, John Turnbull, Rob McKinnon, David J Booth
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243446 (2020)
The common or weedy seadragon, Phyllopteryx taeniolatus, is an iconic and endemic fish found across temperate reefs of southern Australia. Despite its charismatic nature, few studies have been published, and the extent of population sub-structuring r
Externí odkaz:
https://doaj.org/article/2acc74a075ce4605b64bda2437586b44
Publikováno v:
Sensors, Vol 15, Iss 9, Pp 24087-24108 (2015)
In this paper, a three-component decomposition algorithm is proposed for processing compact polarimetric SAR images. By using the correspondence between the covariance matrix and the Stokes vector, three-component scattering models for CTLR and DCP m
Externí odkaz:
https://doaj.org/article/88207d96a7ac46d787cbc377d2ec527f
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171668 (2017)
Sonic hedgehog (Shh) is a morphogen essential to the developing nervous system that continues to play an important role in adult life by contributing to cell proliferation and differentiation, maintaining blood-brain barrier integrity, and being cyto
Externí odkaz:
https://doaj.org/article/cd708239b36f4452811d7c3b2a9d17cc
Autor:
Rosamond Lougheed, John Turnbull
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e23141 (2011)
Methylene blue (MB) is a drug with a long history and good safety profile, and with recently-described features desirable in a treatment for ALS.We tested oral MB in inbred high-copy number SOD1 G93A mice, at 25 mg/kg/day beginning at 45 days of age.
Externí odkaz:
https://doaj.org/article/ad3d9d708bca45a38b2416d1af16ef2e
The Kodak camera, the CT scanner, the steam turbine, the telephone--such inventions not only changed the course of history, but also changed our understanding of what the human race could achieve. An authoritative guide to the remarkable history of h
Autor:
Kelly M, Sunderland, Derek, Beaton, Stephen R, Arnott, Peter, Kleinstiver, Donna, Kwan, Jane M, Lawrence-Dewar, Joel, Ramirez, Brian, Tan, Robert, Bartha, Sandra E, Black, Michael, Borrie, Donald, Brien, Leanne K, Casaubon, Brian C, Coe, Benjamin, Cornish, Allison A, Dilliott, Dar, Dowlatshahi, Elizabeth, Finger, Corinne, Fischer, Andrew, Frank, Julia, Fraser, Morris, Freedman, Barry, Greenberg, David A, Grimes, Ayman, Hassan, Wendy, Hatch, Robert A, Hegele, Christopher, Hudson, Mandar, Jog, Sanjeev, Kumar, Anthony, Lang, Brian, Levine, Wendy, Lou, Jennifer, Mandzia, Connie, Marras, William, McIlroy, Manuel, Montero-Odasso, David G, Munoz, Douglas P, Munoz, Joseph B, Orange, David S, Park, Stephen H, Pasternak, Frederico, Pieruccini-Faria, Tarek K, Rajji, Angela C, Roberts, John F, Robinson, Ekaterina, Rogaeva, Demetrios J, Sahlas, Gustavo, Saposnik, Christopher J M, Scott, Dallas, Seitz, Christen, Shoesmith, Thomas D L, Steeves, Michael J, Strong, Stephen C, Strother, Richard H, Swartz, Sean, Symons, David F, Tang-Wai, Maria Carmela, Tartaglia, Angela K, Troyer, John, Turnbull, Lorne, Zinman, Paula M, McLaughlin, Mario, Masellis, Malcolm A, Binns, Guangyong, Zou
Publikováno v:
Alzheimer's & Dementia. 19:226-243
Understanding synergies between neurodegenerative and cerebrovascular pathologies that modify dementia presentation represents an important knowledge gap.This multi-site, longitudinal, observational cohort study recruited participants across prevalen
Autor:
Di Yu, Nuanyi Liang, Julia Zebarth, Qing Shen, Miracle Ozzoude, Maged Goubran, Jennifer S. Rabin, Joel Ramirez, Christopher J. M. Scott, Fuqiang Gao, Robert Bartha, Sean Symons, Seyyed Mohammad Hassan Haddad, Courtney Berezuk, Brian Tan, Donna Kwan, Robert A. Hegele, Allison A. Dilliott, Nuwan D. Nanayakkara, Malcolm A. Binns, Derek Beaton, Stephen R. Arnott, Jane M. Lawrence‐Dewar, Ayman Hassan, Dar Dowlatshahi, Jennifer Mandzia, Demetrios Sahlas, Leanne Casaubon, Gustavo Saposnik, Yurika Otoki, Krista L. Lanctôt, Mario Masellis, Sandra E. Black, Richard H. Swartz, Ameer Y. Taha, Walter Swardfager, Natalie Rashkovan, Agessandro Abrahao, Lorne Zinman, Alisia Bonnick, Christopher Scott, Melissa Holmes, Sabrina Adamo, Morris Freedman, Mojdeh Zamyadi, Stephen Arnott, Malcolm Binns, Pradeep Raamana, Stephen Strother, Kelly Sunderland, Athena Theyers, Abiramy Uthirakumaran, Brian Levine, Angela Troyer, Michael Strong, Peter Kleinstiver, Michael Borrie, Elizabeth Finger, Christen Shoesmith, Frederico Faria, Manuel Montero‐Odasso, Yanina Sarquis‐Adamson, Alanna Black, Allison Ann Dilliott, Rob Hegele, John Robinson, Sali Farhan, Rob Bartha, Hassan Haddad, Nuwan Nanayakkara, Guangyong Zou, Stephen Pasternak, JB Orange, Angela Roberts, Mandar Jog, Dallas Seitz, Don Brien, Ying Chen, Brian Coe, Doug Munoz, Paula McLaughlin, Alicia Peltsch, Susan Bronskill, Wendy Lou, Sanjeev Kumar, Bruce Pollock, Tarek Rajji, David Tang‐Wai, Carmela Tartaglia, Brenda Varriano, Marvin Chum, John Turnbull, Jane Lawrence‐Dewar, Julia Fraser, Bill McIlroy, Ben Cornish, Karen Van Ooteghem, Chris Hudson, Elena Leontieva, Wendy Hatch, Faryan Tayyari, Sherif Defrawy, Edward Margolin, Efrem Mandelcorn, Barry Greenberg, Anthony Lang, Connie Marras, Andrew Frank, David Grimes, Dennis Bulman, John Woulfe, Mahdi Ghani, Tom Steeves, David Munoz, Corinne Fischer, Ekaterina Rogaeva, Sujeevini Sujanthan, David Breen, Roger A. Dixon
Publikováno v:
Journal of the American Heart Association, vol 12, iss 1
Background Cerebral small vessel disease is associated with higher ratios of soluble‐epoxide hydrolase derived linoleic acid diols (12,13‐dihydroxyoctadecenoic acid [DiHOME] and 9,10‐DiHOME) to their parent epoxides (12(13)‐epoxyoctadecenoic