Zobrazeno 1 - 2
of 2
pro vyhledávání: '"John Tomayko"'
Autor:
Shahul Hameed P, Harish Kotakonda, Sreevalli Sharma, Radha Nandishaiah, Nainesh Katagihallimath, Ranga Rao, Claire Sadler, Ian Slater, Michael Morton, Abhijeeth Chandrasekaran, Ed Griffen, Dhanashree Pillai, Sambasiva Reddy, Nagakumar Bharatham, Suryanarayanan Venkatesan, Venugopal Jonnalagadda, Ramesh Jayaraman, Mahesh Nanjundappa, Maitrayee Sharma, Savitha Raveendran, Sreenath Rajagopal, Harikrishna Tumma, Amy Watters, Holly Becker, Jill Lindley, Robert Flamm, Michael Huband, Dan Sahm, Meredith Hackel, Tarun Mathur, Ruwanthi Kolamunnage-Dona, Jennifer Unsworth, Laura Mcentee, Nikki Farrington, Dhanasekaran Manickam, Narayana Chandrashekara, Sivakandan Jayachandiran, Hrushikesava Reddy, Sathya Shanker, Vijay Richard, Teby Thomas, Savitha Nagaraj, Santanu Datta, Vasan Sambandamurthy, Vasanthi Ramachandran, Robert Clay, John Tomayko, Shampa Das, Balasubramanian V
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The global crisis of antimicrobial resistance (AMR) necessitates the development of broad-spectrum antibacterial drugs effective against multi-drug resistant (MDR) pathogens. BWC0977, a Novel Bacterial Topoisomerase Inhibitor (NBTI) selectiv
Externí odkaz:
https://doaj.org/article/225808750cc14951b6c238bab08ada77
Autor:
Tim Keutzer, Scott Coleman, John Tomayko, Troy Lister, Susannah M. Walpole, Paul B. Eckburg, Luke Utley, Ellen Kopp, Nicholas Farinola
Publikováno v:
Antimicrobial Agents and Chemotherapy
SPR741 is a novel polymyxin B derivative, with minimal intrinsic antibacterial activity and reduced nonclinical nephrotoxicity compared to levels with polymyxin B, that interacts with the outer membrane of Gram-negative bacteria, enhancing penetratio