Zobrazeno 1 - 10
of 23
pro vyhledávání: '"John Tadross"'
Autor:
Manik Garg, Dominique-Laurent Couturier, Jérémie Nsengimana, Nuno A. Fonseca, Matthew Wongchenko, Yibing Yan, Martin Lauss, Göran B. Jönsson, Julia Newton-Bishop, Christine Parkinson, Mark R. Middleton, D. Timothy Bishop, Sarah McDonald, Nikki Stefanos, John Tadross, Ismael A. Vergara, Serigne Lo, Felicity Newell, James S. Wilmott, John F. Thompson, Georgina V. Long, Richard A. Scolyer, Pippa Corrie, David J. Adams, Alvis Brazma, Roy Rabbie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The identification of prognostic biomarkers can help stratify cancer patients. Here, the authors apply deep RNA sequencing from primary melanomas coupled with long-term clinical outcome data from a prospective multicentre phase III trial, to develop
Externí odkaz:
https://doaj.org/article/c4c725539da241dab371faec795d6af6
Autor:
Manik Garg, Dominique-Laurent Couturier, Jérémie Nsengimana, Nuno A. Fonseca, Matthew Wongchenko, Yibing Yan, Martin Lauss, Göran B. Jönsson, Julia Newton-Bishop, Christine Parkinson, Mark R. Middleton, D. Timothy Bishop, Sarah McDonald, Nikki Stefanos, John Tadross, Ismael A. Vergara, Serigne Lo, Felicity Newell, James S. Wilmott, John F. Thompson, Georgina V. Long, Richard A. Scolyer, Pippa Corrie, David J. Adams, Alvis Brazma, Roy Rabbie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/2d36fe56094f405ab8536dfd8423f8a9
Autor:
Sara Kohnke, Sophie Buller, Danae Nuzzaci, Katherine Ridley, Brian Lam, Helena Pivonkova, Marie A. Bentsen, Kimberly M. Alonge, Chao Zhao, John Tadross, Staffan Holmqvist, Takahiro Shimizo, Hannah Hathaway, Huiliang Li, Wendy Macklin, Michael W. Schwartz, William D. Richardson, Giles S.H. Yeo, Robin J.M. Franklin, Ragnhildur T. Karadottir, David H. Rowitch, Clemence Blouet
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109362- (2021)
Summary: The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and median eminence [ME]) is a key nutrient sensing site for the production of the complex homeostatic feedback responses required for the maintenance of energy bala
Externí odkaz:
https://doaj.org/article/5e36423c8b584650a2ec34b1447ad29b
Autor:
Anthony P. Coll, MN Bedenbaugh, DT Porter, David H. Rowitch, John R. B. Perry, D A van Heel, X Dai, Rachel N. Lippert, Debra Rimmington, A. L. Gonçalves Soares, Felix R. Day, Duckett K, Patrick Sweeney, Zhaoyang Xu, Ahsan Nabi Khan, Hilary C. Martin, John Tadross, Roger D. Cone, Brian Y.H. Lam, Klj Ellacott, Richard B. Simerly, J Rosmaninho-Salgado, Alice E. Williamson, Gkc Dowsett, Sarah Finer, Irene Cimino, Giles S.H. Yeo, Audrey Melvin, Kara Rainbow, Claudia Langenberg, Stephen O'Rahilly, Nicholas J. Wareham, Katherine Ridley, Richard C. Trembath, Staffan Holmqvist, Sophie Buller, N J Timpson, Kaitlin H Wade, Ken K. Ong, Elena G. Bochukova
Publikováno v:
Nature
2021, ' MC3R links nutritional state to childhood growth and the timing of puberty ', Nature, vol. 599, no. 7885, pp. 436-441 . https://doi.org/10.1038/s41586-021-04088-9
2021, ' MC3R links nutritional state to childhood growth and the timing of puberty ', Nature, vol. 599, no. 7885, pp. 436-441 . https://doi.org/10.1038/s41586-021-04088-9
The state of somatic energy stores in metazoans is communicated to the brain, which regulates key aspects of behaviour, growth, nutrient partitioning and development1. The central melanocortin system acts through melanocortin 4 receptor (MC4R) to con
Autor:
Isabel Fernandes-Freitas, Alexandra Milona, Jose Ramos-Pittol, Stephen Manchishi, Kara Rainbow, Brian Lam, John Tadross, Anthony Beucher, William Colledge, Ines Cebola, Kevin Murphy, Irene Miguel-Aliaga, Giles Yeo, Waljit Dhillo, Bryn Owen
Publikováno v:
Endocrine Abstracts.
Autor:
David H. Rowitch, William D. Richardson, Clemence Blouet, John Tadross, Giles S.H. Yeo, Sara Kohnke, Ragnhildur Thóra Káradóttir, Sophie Buller, Hannah Hathaway, Danae Nuzzaci, Katherine Ridley, Helena Pivonkova, Michael W. Schwartz, Huiliang Li, Wendy B. Macklin, Robin J.M. Franklin, Marie A. Bentsen, Kimberly M. Alonge, Staffan Holmqvist, Chao Zhao, Takahiro Shimizu, Brian Y.H. Lam
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109362-(2021)
Cell Reports
Cell Reports
Summary The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and median eminence [ME]) is a key nutrient sensing site for the production of the complex homeostatic feedback responses required for the maintenance of energy balan
Autor:
Kent E Pedersen, Hanna Kim, Anthony J. Rostron, Samuel M. Lockhart, Y. C. Loraine Tung, Stephanie Joaquim, Keith Burling, A. John Simpson, Sebastian Beck Jørgensen, Giles Sh Yeo, E-Chiang Lee, Audrey Melvin, Danna M. Breen, Menna R. Clatworthy, Irene Cimino, Kendra K. Bence, Debra Rimmington, Stephen O'Rahilly, Peter Barker, Jonathan M. Scott, André Barros, Ana Neves-Costa, John Tadross, Anthony P. Coll, Luis F. Moita, Hui Liu, Don Bennett, Sara Kohnke
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance GDF15, a hormone produced by a wide variety of cells undergoing different types of stress, acts on a receptor in the brain where it transmits signals that are perceived by the organism as aversive. We now report an action of GDF15, where
Autor:
Lewis Je, Lawrence J. Billing, Bertie Gottgens, Fiona M. Gribble, Christopher A. Smith, John Tadross, Kinston Sj, Cheryl A. Brighton, David Baker, Marco Tripodi, Hornigold D, Woodward Or, Benjamin U. Phillips, Ciabatti E, Alice E. Adriaenssens, Frank Reimann
Relaxin/insulin-like-family peptide receptor-4 (RXFP4), the cognate receptor for insulin-like peptide 5 (INSL5), has been implicated in feeding behaviour as Rxfp4 knockout mice display shorter meal durations and reduced high fat diet (HFD) intake. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d214b52ed8de0495597fbbef94a12b4d
https://doi.org/10.1101/2021.06.26.450020
https://doi.org/10.1101/2021.06.26.450020
Autor:
Anthony P. Coll, John Tadross, Giles S.H. Yeo, Irene Cimino, Lotte Bjerre Knudsen, Georgina K.C. Dowsett, Debra Rimmington, Brian Y.H. Lam, Joseph Polex-Wolf, Charles Pyke
ObjectiveThe area postrema (AP) and the nucleus tractus solitaris (NTS), located in the hindbrain, are key nuclei that sense and integrate peripheral nutritional signals and, consequently, regulate feeding behaviour. While single cell transcriptomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3d09f4e6c1eeed2fb8ce4c510c2387
https://doi.org/10.1101/2021.03.11.434948
https://doi.org/10.1101/2021.03.11.434948
Autor:
D. Timothy Bishop, Felicity Newell, Nikki Stefanos, John F. Thompson, Martin Lauss, Serigne Lo, Ismael A. Vergara, Richard A. Scolyer, Matthew Wongchenko, Manik Garg, Nuno A. Fonseca, Dominique-Laurent Couturier, Yibing Yan, Göran Jönsson, Georgina V. Long, Sarah McDonald, David J. Adams, James S. Wilmott, Mark R. Middleton, Alvis Brazma, Pippa Corrie, Jérémie Nsengimana, John Tadross, Roy Rabbie, Christine Parkinson, Julia Newton-Bishop
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Funder: University of Sydney Medical Foundation
Funder: Department of Health | National Health and Medical Research Council (NHMRC); doi: https://doi.org/10.13039/501100000925
Adjuvant systemic therapies are now routinely used following res
Funder: Department of Health | National Health and Medical Research Council (NHMRC); doi: https://doi.org/10.13039/501100000925
Adjuvant systemic therapies are now routinely used following res