Zobrazeno 1 - 9
of 9
pro vyhledávání: '"John TCHEN"'
Autor:
John TCHEN, Quentin SIMON, Léa CHAPART, Morgane K. THAMINY, Shamila VIBHUSHAN, Loredana SAVEANU, Yasmine LAMRI, Fanny SAIDOUNE, Emeline PACREAU, Christophe PELLEFIGUES, Julie BEX-COUDRAT, Hajime KARASUYAMA, Kensuke MIYAKE, Juan HIDALGO, Padraic G. FALLON, Thomas PAPO, Ulrich BLANK, Marc BENHAMOU, Guillaume HANOUNA, Karim SACRE, Eric DAUGAS, Nicolas CHARLES
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary
Externí odkaz:
https://doaj.org/article/2b261c12033c4401a2b53ad4f143bfa7
Autor:
John Tchen, Quentin Simon, Léa Chapart, Christophe Pellefigues, Hajime Karasuyama, Kensuke Miyake, Ulrich Blank, Marc Benhamou, Eric Daugas, Nicolas Charles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse model allowing expression of both the fluorescent p
Externí odkaz:
https://doaj.org/article/6d84a6fd725646d891b31d23a059b29f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autore
Externí odkaz:
https://doaj.org/article/385df604c19b4f3489d0325aa240165e
Autor:
John TCHEN, Nicolas CHARLES
Publikováno v:
médecine/sciences. 38:366-373
Comprendre les mécanismes physiopathologiques des maladies autoimmunes présentant des auto-anticorps (MAPA) représente un enjeu majeur pour le développement d’approches thérapeutiques innovantes. Sans en connaître précisément les origines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b296e3e9c65f9a85ae9dbdb5836099b0
https://doi.org/10.1051/medsci/2022040
https://doi.org/10.1051/medsci/2022040
Autor:
John Tchen, Quentin Simon, Léa Chapart, Yasmine Lamri, Fanny Saidoune, Emeline Pacreau, Christophe Pellefigues, Julie Bex-Coudrat, Hajime Karasuyama, Kensuke Miyake, Juan Hidalgo, Padraic G. Fallon, Thomas Papo, Ulrich Blank, Marc Benhamou, Guillaume Hanouna, Karim Sacre, Eric Daugas, Nicolas Charles
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibodies raised against nuclear antigens and whose production is promoted by autoreactive T follicular helper (TFH) cells. Basophils, by accumulating in secondary lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89859d8d660a5240c4dd357d58cd075a
https://doi.org/10.1101/2023.01.10.23284399
https://doi.org/10.1101/2023.01.10.23284399
Autor:
John, Tchen, Nicolas, Charles
Publikováno v:
Medecine sciences : M/S. 38(4)
Understanding the pathophysiology of antibody-driven autoimmune diseases (AAID) represents a major challenge for the biomedical community to develop innovative therapeutic strategies that are still lacking to control these diseases. If the reason why
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5da983c7236a1f956e622bf40ffdf4f
https://pubmed.ncbi.nlm.nih.gov/35485897
https://pubmed.ncbi.nlm.nih.gov/35485897
Autor:
Arthur Mageau, John Tchen, Valentine Marie Ferré, Pascale Nicaise-Roland, Diane Descamps, Nicole Delory, Chrystelle François, Celine Mendes, Thomas Papo, Tiphaine Goulenok, Nicolas Charles, Karim Sacré
Publikováno v:
Journal of Autoimmunity. 134:102987
To evaluate the specific response of SLE patients to BNT162b2 vaccination and its impact on autoimmunity defined as in vivo production of interferon-alpha (IFNα) by plasmacytoid dendritic cells (pDCs) and autoreactive immune responses.Our prospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e2d315531d576cf50aa51d40e6ee48
https://doi.org/10.1016/j.jaut.2022.102987
https://doi.org/10.1016/j.jaut.2022.102987
Publikováno v:
Frontiers in immunology. 13
Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2309f993b62a413af12a5ca988e2723b
https://pubmed.ncbi.nlm.nih.gov/35444641
https://pubmed.ncbi.nlm.nih.gov/35444641
Autor:
Gernot Wagner, Nicole Maher, Peter M. Groffman, John Shapiro, Nicholas B. Rajkovich, Deborah Balk, Joel Towers, Justin M. Gundlach, Maureen George, Nancy Holt, Katherine A. McComas, Illya Azaroff, Timon McPhearson, Arthee Jahangir, Adam Parris, William Calabrese, Thomas Matte, Rachel Hogan Carr, Kim Knowlton, Laurie Schoeman, Janice Barnes, John Tchen, Ana Baptista, Kevin A. Reed, Nora I. Kyrkjebo, Thaddeus Pawlowski, Peter J. Marcotullio, Richard H. Moss, Bobuchi Ken-Opurum, Danielle Spiegel-Feld, Radley M. Horton, Treston Codrington, Farzana Gandhi, Christian Braneon, S. Kyle McKay, Guy J.P. Nordenson, Jessica Colon, Robin Leichenko
Publikováno v:
Journal of Extreme Events.
In May 2020, the New York City (NYC) Mayor’s Office of Climate Resiliency (MOCR) began convening bi-weekly discussions, called the Rapid Research and Assessment (RRA) Series, between City staff and external experts in science, policy, design, engin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2490b9afa0ad8d0b90cd8c3b949bfa
https://doi.org/10.1142/s234573762150010x
https://doi.org/10.1142/s234573762150010x