Zobrazeno 1 - 10 of 50 pro vyhledávání: '"John T. Ruzinski"'
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Assessment of kidney proximal tubular secretion in critical illness
Autor: Mark M. Wurfel, Pavan K. Bhatraju, Jonathan Himmelfarb, Andrew N. Hoofnagle, Neha A. Sathe, Edward D. Siew, Bryan Kestenbaum, Xin-Ya Chai, John T. Ruzinski
Publikováno v: JCI Insight
BACKGROUND Serum creatinine concentrations (SCrs) are used to determine the presence and severity of acute kidney injury (AKI). SCr is primarily eliminated by glomerular filtration; however, most mechanisms of AKI in critical illness involve kidney p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35af0328040bfc35d779c4321567f97
https://pubmed.ncbi.nlm.nih.gov/33886506
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4
1061-P: Effects of Long-Term Vitamin D and Omega-3 Fatty Acid Supplementation on Inflammatory and Cardiac Biomarkers in Patients with Type 2 Diabetes
Autor: Ian H. de Boer, Julie E. Buring, Michal L. Melamed, Ravi Thadhani, Leila R. Zelnick, Howard D. Sesso, JoAnn E. Manson, Andrew N. Hoofnagle, I-Min Lee, Christine P. Limonte, John T. Ruzinski
Publikováno v: Diabetes. 69
Background: Immune system activation contributes to the development of microvascular and macrovascular complications in diabetes. Identifying interventions that reduce inflammation may delay progression of diabetes complications. Methods: This study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ae993bec798f2ab3a9daacca0a43ab0
https://doi.org/10.2337/db20-1061-p
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5
Vitamin D and omega-3 trial to prevent and treat diabetic kidney disease: Rationale, design, and baseline characteristics
Autor: Robert J. Glynn, Julie Lin, Ian H. de Boer, Leila R. Zelnick, Howard D. Sesso, Georgina Friedenberg, Lu Wang, Debra A. Schaumberg, JoAnn E. Manson, Andrew N. Hoofnagle, Julie E. Buring, John T. Ruzinski, Vadim Bubes, Ravi Thadhani, Julie Duszlak
Publikováno v: Contemporary Clinical Trials. 74:11-17
Diabetic kidney disease (DKD), defined as reduced glomerular filtration rate (GFR), elevated urine albumin excretion, or both that is clinically attributable to diabetes, is a common and morbid diabetes complication. Animal-experimental data, observa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126cc7e3caec6f43efe12e1915f07fe3
https://doi.org/10.1016/j.cct.2018.09.014
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6
Akademický článek
Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model.
Autor: Fiona E Lovegrove, Sina A Gharib, Lourdes Peña-Castillo, Samir N Patel, John T Ruzinski, Timothy R Hughes, W Conrad Liles, Kevin C Kain
Publikováno v: PLoS Pathogens, Vol 4, Iss 5, p e1000068 (2008)
Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes suc
Externí odkaz: https://doaj.org/article/d35bd3a923d84d61a17774f98c1df247
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7
Urine RAS components in mice and people with type 1 diabetes and chronic kidney disease
Autor: Anne Goodling, Jan Wysocki, John T. Ruzinski, Maryam Afkarian, Daniel Batlle, Kathryn B. Whitlock, Mar Burgaya
Publikováno v: American Journal of Physiology-Renal Physiology. 313:F487-F494
The pathways implicated in diabetic kidney disease (DKD) are largely derived from animal models. To examine if alterations in renin-angiotensin system (RAS) in humans are concordant with those in rodent models, we measured concentration of angiotensi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cf38106aa90439ae4725b8121a094a
https://doi.org/10.1152/ajprenal.00074.2017
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Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial
Autor: Matthew B. Rivara, Brian Phillips, Lori Linke, Danny D. Shen, John T. Ruzinski, T. Alp Ikizler, Catherine K. Yeung, Denise Rock, Cassianne Robinson-Cohen, Jonathan Himmelfarb
Publikováno v: American Journal of Kidney Diseases. 69:389-399
Background Oxidative stress is highly prevalent in patients with end-stage renal disease and is linked to excess cardiovascular risk. Identifying therapies that reduce oxidative stress has the potential to improve cardiovascular outcomes in patients
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cf0ef9d6267c4afb228977e29e9ce7
https://doi.org/10.1053/j.ajkd.2016.08.041
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Dietary Acid Load is Associated With Serum Bicarbonate but not Insulin Sensitivity in Chronic Kidney Disease
Autor: Bryan Kestenbaum, Laura Curtin, Ian H. de Boer, Kristina M. Utzschneider, Jonathan Himmelfarb, Halil O. Ikizler, John T. Ruzinski, Leila R. Zelnick
Publikováno v: Journal of Renal Nutrition. 26:93-102
Objective In chronic kidney disease (CKD), dietary acid may promote metabolic acidosis and insulin resistance, which in turn may contribute to adverse clinical health outcomes. We examined associations between dietary acid load, serum bicarbonate, an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be2ba6943957e7b6653dda27e305b13
https://doi.org/10.1053/j.jrn.2015.08.008
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