Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John T. Gonzalez"'
Autor:
Inmaculada Ruz-Maldonado, John T. Gonzalez, Hanming Zhang, Jonathan Sun, Alicia Bort, Inamul Kabir, Richard G. Kibbey, Yajaira Suárez, Daniel M. Greif, Carlos Fernández-Hernando
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Midlobular hepatocytes are proposed to be the most plastic hepatic cell, providing a reservoir for hepatocyte proliferation during homeostasis and regeneration. However, other mechanisms beyond hyperplasia have been little explored and the c
Externí odkaz:
https://doaj.org/article/464ecf555656487594404e7c594fa8c7
Autor:
Yulia Rybakova, John T. Gonzalez, Roman Bogorad, Vikash P. Chauhan, Yize L. Dong, Charles A. Whittaker, Timofei Zatsepin, Victor Koteliansky, Daniel G. Anderson
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-14 (2021)
Abstract Genomic studies have significantly improved our understanding of hepatocellular carcinoma (HCC) biology and have led to the discovery of multiple protein-coding genes driving hepatocarcinogenesis. In addition, these studies have identified t
Externí odkaz:
https://doaj.org/article/e50c0d26f6e64a93bed118ec9c0c0a87
Autor:
Matthew G. Booty, Kelan A. Hlavaty, Adam Stockmann, Emrah Ilker Ozay, Carolyne Smith, Lina Tian, Edylle How, Disha Subramanya, Anita Venkitaraman, Christian Yee, Olivia Pryor, Kelly Volk, Katarina Blagovic, Ildefonso Vicente-Suarez, Defne Yarar, Melissa Myint, Amy Merino, Jonathan Chow, Tarek Abdeljawad, Harry An, Sophia Liu, Shirley Mao, Megan Heimann, LeeAnn Talarico, Miye K. Jacques, Eritza Chong, Lucas Pomerance, John T. Gonzalez, Ulrich H. von Andrian, Klavs F. Jensen, Robert Langer, Hendrik Knoetgen, Christine Trumpfheller, Pablo Umaña, Howard Bernstein, Armon Sharei, Scott M. Loughhead
Publikováno v:
The Journal of Immunology. 208:929-940
CD8+ T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced the activity of existing CD8+ T cell responses, therapeutic approaches to generate Ag-spec
Autor:
Matthew G, Booty, Kelan A, Hlavaty, Adam, Stockmann, Emrah Ilker, Ozay, Carolyne, Smith, Lina, Tian, Edylle, How, Disha, Subramanya, Anita, Venkitaraman, Christian, Yee, Olivia, Pryor, Kelly, Volk, Katarina, Blagovic, Ildefonso, Vicente-Suarez, Defne, Yarar, Melissa, Myint, Amy, Merino, Jonathan, Chow, Tarek, Abdeljawad, Harry, An, Sophia, Liu, Shirley, Mao, Megan, Heimann, LeeAnn, Talarico, Miye K, Jacques, Eritza, Chong, Lucas, Pomerance, John T, Gonzalez, Ulrich H, von Andrian, Klavs F, Jensen, Robert, Langer, Hendrik, Knoetgen, Christine, Trumpfheller, Pablo, Umaña, Howard, Bernstein, Armon, Sharei, Scott M, Loughhead
Publikováno v:
J Immunol
CD8(+) T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced the activity of existing CD8(+) T cell responses, therapeutic approaches to generate Ag-
Autor:
Daniel G. Anderson, Charles A. Whittaker, Vikash P. Chauhan, Victor Koteliansky, Yulia Rybakova, John T. Gonzalez, Yize L. Dong, Roman L. Bogorad
Genomic studies have significantly improved our understanding of hepatocellular carcinoma (HCC) biology and have led to the discovery of multiple protein-coding genes driving hepatocarcinogenesis. In addition, these studies have identified thousands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762c06ad3d85735c827105f929bb3faa
https://doi.org/10.1101/2020.07.01.181693
https://doi.org/10.1101/2020.07.01.181693
Autor:
Daniel G. Anderson, Yulia Rybakova, Michael W. Heartlein, John T. Gonzalez, Piotr S. Kowalski, Frank Derosa, Derfogail Delcassian, Yuxuan Huang
Publikováno v:
Mol Ther
Molecular Therapy
Molecular Therapy
Antibody-based drugs are a leading class of biologics used to treat a variety of diseases, including cancer. However, wide antibody implementation is hindered by manufacturing challenges and high production cost. Use of in-vitro-transcribed mRNA (IVT