Zobrazeno 1 - 10
of 60
pro vyhledávání: '"John T. Gatzy"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 275:L1095-L1099
Inhibitors of Cl− and[Formula: see text] secretion reduce acetylcholine-induced liquid, but not mucin, secretion by bronchial submucosal glands [S. K. Inglis, M. R. Corboz, A. E. Taylor, and S. T. Ballard. Am. J. Physiol. 272 ( Lung Cell. Mol. Phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e2d8d5a743b2e59db370ac5e1a687a
https://doi.org/10.1152/ajplung.1998.275.6.l1095
https://doi.org/10.1152/ajplung.1998.275.6.l1095
Autor:
Hirotoshi Matsui, Robert Tarran, Richard C. Boucher, Barbara R. Grubb, Scott H. Randell, John T. Gatzy, C. William Davis
Publikováno v:
Cell. 95(7):1005-1015
The pathogenesis of cystic fibrosis (CF) airways infection is unknown. Two hypotheses, “hypotonic [low salt]/defensin” and “isotonic volume transport/mucus clearance,” attempt to link defects in cystic fibrosis transmembrane conductance regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f8996fe2119594e26fd9c7a60694e9
Autor:
Pierre M. Barker, Beverly H. Koller, Edith Hummler, MyTrang Nguyen, Richard C. Boucher, Hilary Norman, Barbara R. Grubb, John T. Gatzy, Bernard C. Rossier
Publikováno v:
Journal of Clinical Investigation. 102:1634-1640
Genetic evidence supports a critical role for the epithelial sodium channel (ENaC) in both clearance of fetal lung liquid at birth and total body electrolyte homeostasis. Evidence from heterologous expression systems suggests that expression of the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52329bad948c44fce82c68a630f5670a
https://doi.org/10.1172/jci3971
https://doi.org/10.1172/jci3971
Effects of Adenosine, ATP, and UTP on Chloride Secretion by Epithelia Explanted from Fetal Rat Lung1
Autor:
Pierre M. Barker, John T. Gatzy
Publikováno v:
Pediatric Research. 43:652-659
Effects of Adenosine, ATP, and UTP on Chloride Secretion by Epithelia Explanted from Fetal Rat Lung 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48cadcc283a0a7e77703b21ba755c5e
https://doi.org/10.1203/00006450-199805000-00014
https://doi.org/10.1203/00006450-199805000-00014
Autor:
Robert E. Wood, Charles A. Pue, John T. Gatzy, Michael R. Knowles, Joseph M. Robinson, William M. Mentz, Gilbert C. Wager, Richard C. Boucher
Publikováno v:
Journal of Clinical Investigation. 100:2588-2595
To test whether a major contribution of airways epithelial ion transport to lung defense reflects the regulation of airway surface liquid (ASL) ionic composition, we measured ASL composition using the filter paper technique. On nasal surfaces, the Cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d683c8456aef79025cb971482571ec9c
https://doi.org/10.1172/jci119802
https://doi.org/10.1172/jci119802
Autor:
Richard C. Boucher, Bernard C. Rossier, Chantal Verdumo, Colleen L. Talbot, Barbara R. Grubb, Pierre M. Barker, Qing Wang, Friedrich Beermann, Jean Daniel Horisberger, John T. Gatzy, Edith Hummler, Michel Burnier
Publikováno v:
Proceedings of the National Academy of Sciences. 94:11710-11715
Aldosterone-dependent epithelial sodium transport in the distal nephron is mediated by the absorption of sodium through the highly selective, amiloride-sensitive epithelial sodium channel (ENaC) made of three homologous subunits (α, β, and γ). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e408b6d6269709c5754e0be4ded6359
https://doi.org/10.1073/pnas.94.21.11710
https://doi.org/10.1073/pnas.94.21.11710
Autor:
T L O'Connell, John C. Olsen, M. J. Stutts, John T. Gatzy, R. C. Boucher, Sherif E. Gabriel, Elmer M. Price
Publikováno v:
Journal of Biological Chemistry. 268:20653-20658
We studied the consequences of cystic fibrosis transmembrane conductance regulator (CFTR) expression in NIH-3T3 fibroblasts as a model for the effects of virally transduced CFTR expression in non-epithelial cells. Fibroblasts were infected with a ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a836de2581883189183ed621affe53
https://doi.org/10.1016/s0021-9258(20)80774-1
https://doi.org/10.1016/s0021-9258(20)80774-1
Publikováno v:
The Journal of Physiology. 463:647-665
1. Fetal rat tracheas and lung buds form liquid-filled cysts in submersion culture. The volume that accumulates in cysts is driven by active Cl- secretion. 2. We examined the effects, on these explants, of hormones that induce liquid absorption by fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c277aabe4272c897e178533f9dd487
https://doi.org/10.1113/jphysiol.1993.sp019615
https://doi.org/10.1113/jphysiol.1993.sp019615
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 262:L628-L636
In vivo studies of fetal sheep suggest that the liquid present in the lumen of the lung throughout fetal life is derived from Cl- secretion by the pulmonary epithelium. Monolayer preparations of enriched epithelial cells from distal fetal rat (18-day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa94e9a77379a99db42a41e79a74b413
https://doi.org/10.1152/ajplung.1992.262.5.l628
https://doi.org/10.1152/ajplung.1992.262.5.l628
Autor:
John T. Gatzy
Publikováno v:
Ciba Foundation Symposium 38-Lung Liquids
The simple architecture of the amphibian lung makes it possible to study the movement of substances across a barrier with permeability and bioelectric properties that are dominated by the alveolar epithelium. When mounted as a planar sheet between id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32da5f2e99cb8dfe8de05375922d22f
https://doi.org/10.1002/9780470720202.ch11
https://doi.org/10.1002/9780470720202.ch11
