Zobrazeno 1 - 10
of 71
pro vyhledávání: '"John T O'Malley"'
Autor:
Gil Yosipovitch, Nicholas Mollanazar, Sonja Ständer, Shawn G. Kwatra, Brian S. Kim, Elizabeth Laws, Leda P. Mannent, Nikhil Amin, Bolanle Akinlade, Heribert W. Staudinger, Naimish Patel, George D. Yancopoulos, David M. Weinreich, Sheldon Wang, Genming Shi, Ashish Bansal, John T. O’Malley
Publikováno v:
Nature Medicine. 29:1180-1190
Prurigo nodularis (PN) is a chronic inflammatory skin disease with intensely pruritic nodules. The LIBERTY-PN PRIME and PRIME2 phase 3 trials enrolled adults with PN with ≥20 nodules and severe itch uncontrolled with topical therapies. Dupilumab, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4f5b6702cf2718a66378e381a528bc
https://doi.org/10.1038/s41591-023-02320-9
https://doi.org/10.1038/s41591-023-02320-9
Autor:
Ahmed Gehad, Jessica E. Teague, Tiago R. Matos, Victor Huang, Chao Yang, Rei Watanabe, John T. O'Malley, Cornelia L. Trimble, Thomas S. Kupper, Rachael A. Clark
Publikováno v:
Blood Advances, Vol 2, Iss 3, Pp 292-298 (2018)
Abstract: Central memory T cells (TCM) patrol lymph nodes, providing central immunosurveillance against known pathogens, but have not been described as conducting primary tissue immunosurveillance. We analyzed the expression of tissue-homing addressi
Externí odkaz:
https://doaj.org/article/2eb7619042f74b5d877724076f842e8e
Autor:
Yan Zhao, Li-Ming Wu, Qian-Jin Lu, Xing-Hua Gao, Xiao-Hong Zhu, Xu Yao, Lin-Feng Li, Wei Li, Yang-Feng Ding, Zhi-Qiang Song, Ling-Ling Liu, Ning-Ning Dang, Chun-Lei Zhang, Xiao-Ming Liu, Jun Gu, Jin-Yan Wang, Song-Mei Geng, Quan-Zhong Liu, Yi-Feng Guo, Li Dong, Shelley Li, Christine Xu, John T. O’Malley, Elizabeth Laws, Nikhil Amin, Ashish Bansal, Min Wang, Jian-Zhong Zhang
Publikováno v:
International Journal of Dermatology and Venereology. 5:218-225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd082d354c035077bf995d3cdc0bf47d
https://doi.org/10.1097/jd9.0000000000000264
https://doi.org/10.1097/jd9.0000000000000264
Autor:
Amy S Paller, Eric L Simpson, Elaine C Siegfried, Michael J Cork, Andreas Wollenberg, Peter D Arkwright, Weily Soong, Mercedes E Gonzalez, Lynda C Schneider, Robert Sidbury, Benjamin Lockshin, Steven Meltzer, Zhixiao Wang, Leda P Mannent, Nikhil Amin, Yiping Sun, Elizabeth Laws, Bolanle Akinlade, Myles Dillon, Matthew P Kosloski, Mohamed A Kamal, Ariane Dubost-Brama, Naimish Patel, David M Weinreich, George D Yancopoulos, John T O’Malley, Ashish Bansal, Amber Pepper, David Cohen, David Pariser, Jeffrey Leflein, Jeffrey Weinberg, John Browning, Joyce Teng, Lara Wine Lee, Lawrence Sher, Lucia Diaz, Lynda Schneider, Ned Rupp, Peck Ong, Robert Cartwright, Andreas Pinter, Christina Schnopp, Anna Korkosz, Dorota Bystrzanowska, Ewa Sygula, Jacek Zdybski, Kamila Padlewska
Publikováno v:
The Lancet. 400:908-919
Current systemic treatments for children younger than 6 years with moderate-to-severe atopic dermatitis that is uncontrolled with topical therapies might have suboptimal efficacy and safety. Dupilumab is approved for older children and adults with at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d45214d2134d389bfe62af4219892e0
https://doi.org/10.1016/s0140-6736(22)01539-2
https://doi.org/10.1016/s0140-6736(22)01539-2
Autor:
Andrew Blauvelt, Emma Guttman-Yassky, Amy S. Paller, Eric L. Simpson, Michael J. Cork, Jamie Weisman, John Browning, Weily Soong, Xian Sun, Zhen Chen, Matthew P. Kosloski, Mohamed A. Kamal, Dimittri Delevry, Chien-Chia Chuang, John T. O’Malley, Ashish Bansal
Publikováno v:
American Journal of Clinical Dermatology. 23:365-383
For adolescent patients (aged ≥ 12 to 18 years) with uncontrolled moderate-to-severe atopic dermatitis (AD), 16 weeks of treatment with dupilumab resulted in substantial clinical benefit compared with placebo, with an acceptable safety profile. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3b43d5524b78563638d72474b8e3b2
https://doi.org/10.1007/s40257-022-00683-2
https://doi.org/10.1007/s40257-022-00683-2
Autor:
Michael E. Wechsler, Adelmir Souza-Machado, Christine Xu, Xuezhou Mao, Upender Kapoor, Faisal A. Khokhar, John T. O’Malley, Christopher D. Petro, Veronica Mas Casullo, Leda P. Mannent, Paul J. Rowe, Juby A. Jacob-Nara, Marcella Ruddy, Elizabeth Laws, Lisa A. Purcell, Megan Hardin
Publikováno v:
Journal of Allergy and Clinical Immunology: Global. 1:9-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9f4ec81db9000a1fddc03ceb56b9f84
https://doi.org/10.1016/j.jacig.2021.12.003
https://doi.org/10.1016/j.jacig.2021.12.003
Autor:
Rachael A. Clark, Phillip M. Devlin, Thomas S. Kupper, David C. Fisher, Jessica E. Teague, Edward Seger, Ahmed Gehad, Cecilia Larocca, Nicole R. LeBoeuf, Anita Giobbie-Hurder, Elizabeth L. Lowry, Adele de Masson, John T. O'Malley
Supplemental Tables S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8817e1dafe7ca4e1c5e2a3412fad15
https://doi.org/10.1158/1078-0432.22472739
https://doi.org/10.1158/1078-0432.22472739
Autor:
Rachael A. Clark, Phillip M. Devlin, Thomas S. Kupper, David C. Fisher, Jessica E. Teague, Edward Seger, Ahmed Gehad, Cecilia Larocca, Nicole R. LeBoeuf, Anita Giobbie-Hurder, Elizabeth L. Lowry, Adele de Masson, John T. O'Malley
Purpose:Mycosis fungoides is the most common subtype of cutaneous T-cell lymphoma. Skin-directed treatments often improve but do not cure mycosis fungoides skin lesions. The purpose of this study was to (i) assess whether remission was associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f766501da209ced6f00de1067f958d7
https://doi.org/10.1158/1078-0432.c.6528315
https://doi.org/10.1158/1078-0432.c.6528315
Autor:
Peter Wolf, Robert Gniadecki, John T. O'Malley, Niels Odum, Lorenzo Cerroni, Regina Fink-Puches, Simon Fredholm, David Gram Naym, Tianling Wei, Pablo A. Vieyra-Garcia
Primer list Patient detailed information Supplementary table 1: Primer list Supplementary table 2: Set of samples from archived materials Supplementary table 3: Set of samples from clinical PUVA trial (NCT0168659) Supplementary Figure 1. A) Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3ab9250843b6c76349dd8c9d60ec70
https://doi.org/10.1158/1078-0432.22456424
https://doi.org/10.1158/1078-0432.22456424
Autor:
Peter Wolf, Robert Gniadecki, John T. O'Malley, Niels Odum, Lorenzo Cerroni, Regina Fink-Puches, Simon Fredholm, David Gram Naym, Tianling Wei, Pablo A. Vieyra-Garcia
Purpose: Sustained inflammation is a key feature of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL). Resident IL9–producing T cells have been found in skin infections and certain inflammatory skin diseases, but thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36067b75be0fd5c39f3d1695f0d3b6e
https://doi.org/10.1158/1078-0432.c.6523310
https://doi.org/10.1158/1078-0432.c.6523310