Zobrazeno 1 - 10
of 162
pro vyhledávání: '"John T Lucas"'
Autor:
Soleil Hernandez, Hester Burger, Callistus Nguyen, Arnold C. Paulino, John T. Lucas, Austin M. Faught, Jack Duryea, Tucker Netherton, Dong Joo Rhee, Carlos Cardenas, Rebecca Howell, David Fuentes, Julianne Pollard-Larkin, Laurence Court, Jeannette Parkes
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeTreatment planning for craniospinal irradiation (CSI) is complex and time-consuming, especially for resource-constrained centers. To alleviate demanding workflows, we successfully automated the pediatric CSI planning pipeline in previous work.
Externí odkaz:
https://doaj.org/article/8e1a3bf0c48f4616a6c18dc19d857e40
Autor:
John DeSisto, John T. Lucas, Ke Xu, Andrew Donson, Tong Lin, Bridget Sanford, Gang Wu, Quynh T. Tran, Dale Hedges, Chih-Yang Hsu, Gregory T. Armstrong, Michael Arnold, Smita Bhatia, Patrick Flannery, Rakeb Lemma, Lakotah Hardie, Ulrich Schüller, Sujatha Venkataraman, Lindsey M. Hoffman, Kathleen Dorris, Jean M. Mulcahy Levy, Todd C. Hankinson, Michael Handler, Arthur K. Liu, Nicholas Foreman, Rajeev Vibhakar, Kenneth Jones, Sariah Allen, Jinghui Zhang, Suzanne J. Baker, Thomas E. Merchant, Brent A. Orr, Adam L. Green
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Radiation-induced high-grade gliomas (RIGs) are an incurable late complication of cranial radiation therapy. In the largest study to date, we report the results of DNA methylation profiling, RNA-Seq and genomic sequencing of 32 RIG tumors, and an in
Externí odkaz:
https://doaj.org/article/83b97f7c6e28476688641217970f4a3f
Autor:
John T. Lucas, Austin M. Faught, Chih Yang Hsu, Lydia J. Wilson, Yian Guo, Yimei Li, Raja Khan, Jared B. Becksfort, David A. LeVine, Yousef Ismael, Kaleb Darrow, Vadim P. Moskvin, Fakhriddin Pirlepesov, Paul Klimo, Lucas Elijovich, Daniel J. Indelicato, Fredrick A. Boop, Thomas E. Merchant
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 113:152-160
Publikováno v:
Neuro-Oncology Advances. 5
Background Radiogenomic studies of adult-type diffuse gliomas have used magnetic resonance imaging (MRI) data to infer tumor attributes, including abnormalities such as IDH-mutation status and 1p19q deletion. This approach is effective but does not g
Publikováno v:
Journal of Pediatric Neurology. 20:304-308
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a symptom complex of transient neurological deficits, headache, and abnormal cortical contrast enhancement on brain MRI. Pathophysiology is unclear, but exposure to cranial radi
Autor:
John T Lucas, Christopher L Tinkle, Jie Huang, Arzu Onar-Thomas, Sudharsan Srinivasan, Parker Tumlin, Jared B Becksfort, Paul Klimo, Frederick A Boop, Giles W Robinson, Brent A Orr, Julie H Harreld, Matthew J Krasin, Paul A Northcott, David W Ellison, Amar Gajjar, Thomas E Merchant
Publikováno v:
Neuro Oncol
Background We characterize the patterns of progression across medulloblastoma (MB) clinical risk and molecular subgroups from SJMB03, a Phase III clinical trial. Methods One hundred and fifty-five pediatric patients with newly diagnosed MB were treat
Autor:
Robert L. Davis, Fatma Güntürkün, Daniel A. Mulrooney, Elsayed Z. Soliman, Kirsten K. Ness, John T. Lucas, Gregory T. Armstrong, Melissa M. Hudson, Rebecca M. Howell, Leslie L. Robison, Ibrahim Karabayir, John L. Jefferies, Deo Kumar Srivastava, Oguz Akbilgic
Publikováno v:
JCO Clin Cancer Inform
PURPOSE Early identification of childhood cancer survivors at high risk for treatment-related cardiomyopathy may improve outcomes by enabling intervention before development of heart failure. We implemented artificial intelligence (AI) methods using
Autor:
John T. Lucas, Matthew Marker, Jared Becksfort, Tushar Patni, Austin M. Faught, Christopher L. Tinkle, Valerie J. Groben, Elizabeth Burghen, Haley Ruleman, Chia-Ho Hua, Sue C. Kaste, Sahaja Acharya, Noah D. Sabin, Melissa Hudson, Shengjie Wu, Yimei Li, Matthew J. Krasin, Thomas E. Merchant
ImportanceEarly reports suggest adverse events following proton therapy (PT) for childhood cancer are more prevalent given the increased number of PT centers and use in clinical trials.ObjectiveTo assess treatment-failure and toxicity events followin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bf4c182341368b6cb3e0a9b2c2bba8
https://doi.org/10.1101/2022.11.28.22282836
https://doi.org/10.1101/2022.11.28.22282836
Autor:
Fakhriddin Pirlepesov, Lydia Wilson, Vadim P. Moskvin, Alex Breuer, Franz Parkins, John T. Lucas, Thomas E. Merchant, Austin M. Faught
Publikováno v:
Med Phys
PURPOSE: Challenges in proton therapy include identifying patients most likely to benefit; ensuring consistent, high-quality plans as its adoption becomes more widespread; and recognizing biological uncertainties that may be related to increased rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c84bf2cf4274ea1df11dcdfebda2116
https://europepmc.org/articles/PMC9872814/
https://europepmc.org/articles/PMC9872814/
Autor:
Stephanie A. Terezakis, Louis S. Constine, Jamie E. Flerlage, Bradford S. Hoppe, Karin Dieckmann, Eve Gallop-Evans, David R. W. Hodgson, John T. Lucas, Monika L. Metzger, Matthew Hall
Publikováno v:
International journal of radiation oncology, biology, physics
Radiotherapy (RT) technology and utilization has considerably evolved over the last 50 years in the management of pediatric Hodgkin lymphoma (HL). In response to significant late effects from RT in HL survivors, clinical trials in the United States a