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World Status of Monitoring of Iodine Deficiency Disorders Control Programs

Autor: François Delange, Hans Bürgi, Zu Pei Chen, John T. Dunn

Publikováno v: Thyroid. 12:915-924

Monitoring and evaluation are the last phases of a national iodine deficiency disorders (IDD) control program but among the most important. This paper summarizes the latest recommendations by the World Health Organization (WHO), the United Nations Ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3751f4f21ee4749c96deda78aa346cb8
https://doi.org/10.1089/105072502761016557

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Damaged Reproduction: The Most Important Consequence of Iodine Deficiency

Autor: François Delange, John T. Dunn

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:2360-2363

In 1998, over one third of the world’s population lived in areas of iodine deficiency (1). Most countries, including many in western Europe, are involved. Iodine is an essential component of thyroid hormones, and its importance stems from that role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95e54288e1c954a412b2efad4c0a5f0
https://doi.org/10.1210/jcem.86.6.7611

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Iodine Deficiency in the World: Where Do we Stand at the Turn of the Century?

Autor: Eduardo A. Pretell, François Delange, Bruno de Benoist, John T. Dunn

Publikováno v: Thyroid. 11:437-447

Iodine deficiency is the leading cause of preventable mental retardation. Universal salt iodization (USI), calling for all salt used in agriculture, food processing, catering and household to be iodized, is the agreed strategy for achieving iodine su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f511ae2bb0a1878bd2934ee6c3a6b901
https://doi.org/10.1089/105072501300176390

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Update on Intrathyroidal Iodine Metabolism

Autor: John T. Dunn, Ann D. Dunn

Publikováno v: Thyroid. 11:407-414

The thyroid concentrates iodide from the serum and oxidizes it at the apical membrane, attaching it to tyrosyl residues within thyroglobulin (Tg) to make diiodotyrosine and monoiodotyrosine. Major players in this process are Tg, thyroperoxidase (TPO)

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https://doi.org/10.1089/105072501300176363

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Iodine Nutrition and the Risk from Radioactive Iodine: A Workshop Report in the Chernobyl Long-Term Follow-Up Study

Autor: Jacob Robbins, Kevin M. Sullivan, Sergey Petrenko, Victor Kravchenko, Lester VanMiddlesworth, André Bouville, Jay H. Lubin, J. Wolff, John T. Dunn

Publikováno v: Thyroid. 11:487-491

The major fallout of radionuclides from the nuclear power station accident at Chernobyl on 26 April, 1986, occurred in regions of Ukraine and Belarus that are believed to be moderately deficient in dietary iodine. On 17 November, 2000, in conjunction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8433d9f1aaed87db7dc16ddb2d67a9
https://doi.org/10.1089/105072501300176444

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The importance of thyroglobulin structure for thyroid hormone biosynthesis**We shared with our friend and colleague, the late Gaetano Salvatore, a long–standing interest in thyroglobulin structure, as well as a broader interest in the optimal production of thyroid hormone and its dependence on adequate iodine supply. Over the years, we frequently discussed progress in this field with him and his many co–workers. We now welcome the opportunity to review some of our investigative work in one of his favorite fields, in his honor

Autor: Ann D. Dunn, John T. Dunn

Publikováno v: Biochimie. 81:505-509

Thyroglobulin (Tg) is the most important protein in the thyroid because it provides the matrix for thyroid hormone biosynthesis. Here we review experimental work, principally from our laboratory, on the relationship between Tg structure and hormonoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad2a62af0a9f373eb16fd743acd88541
https://doi.org/10.1016/s0300-9084(99)80102-3

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Preoperative evaluation and predictive value of fine-needle aspiration and frozen section of thyroid nodules

Autor: Henry F. Frierson, Richard C. Earnhardt, Loretta A Boyd, John T. Dunn, John B. Hanks

Publikováno v: Journal of the American College of Surgeons. 187:494-502

Background: We sought to evaluate the predictive value of preoperative fine-needle aspiration (FNA) on surgical decision making by evaluating the final pathologic diagnosis and comparing it to the preoperative diagnosis. Further, we wished to calcula

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https://doi.org/10.1016/s1072-7515(98)00221-x

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Intermittent oral administration of potassium iodide solution for the correction of iodine deficiency

Autor: Charles Todd, John T Dunn

Publikováno v: The American Journal of Clinical Nutrition. 67:1279-1283

Iodized salt and iodized oil are the main methods used to prevent iodine deficiency, but sometimes alternative approaches are needed. We tested the efficacy of various regimens for the intermittent administration of potassium iodide in Hwedza, Zimbab

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https://doi.org/10.1093/ajcn/67.6.1279

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Iodine Supplementation for Pregnancy and Lactation—United States and Canada: Recommendations of the American Thyroid Association

Autor: Steven H. Lamm, François Delange, David V. Becker, John T. Dunn, Joseph G. Hollowell, Jayne A. Franklyn, Joanne Rovet, Lewis E. Braverman, Elizabeth N. Pearce, Marvin L. Mitchell, Jacob Robbins

Publikováno v: Thyroid. 16:949-951

The fetus is totally dependent in early pregnancy on maternal thyroxine for normal brain development. Adequate maternal dietary intake of iodine during pregnancy is essential for maternal thyroxine production and later for thyroid function in the fet

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https://doi.org/10.1089/thy.2006.16.949

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Seven deadly sins in confronting endemic iodine deficiency, and how to avoid them

Autor: John T. Dunn

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 81:1332-1335

Iodine deficiency is a problem for almost all countries of the world. Goiter is its most obvious consequence, but others do more damage, particularly effects on the developing brain. In 1990, most countries and international agencies pledged the virt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0d81e349eb4606c5a272789f8cc2f2
https://doi.org/10.1210/jcem.81.4.8636328

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